Search Results - "GOOLEY, Theodore A"
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Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood
Published in Blood (25-11-2010)“…Effectiveness of double umbilical cord blood (dUCB) grafts relative to conventional marrow and mobilized peripheral blood from related and unrelated donors has…”
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2
Concurrent Trastuzumab and HER2/neu-Specific Vaccination in Patients With Metastatic Breast Cancer
Published in Journal of clinical oncology (01-10-2009)“…The primary objectives of this phase I/II study were to evaluate the safety and immunogenicity of combination therapy consisting of concurrent trastuzumab and…”
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3
Pretransplant comorbidities predict severity of acute graft-versus-host disease and subsequent mortality
Published in Blood (10-07-2014)“…Whether the hematopoietic cell transplantation comorbidity index (HCT-CI) can provide prognostic information about development of acute graft-versus-host…”
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4
Prophylactic administration of imatinib after hematopoietic cell transplantation for high-risk Philadelphia chromosome–positive leukemia
Published in Blood (01-04-2007)“…Relapse occurs frequently after allogeneic hematopoietic cell transplantation (HCT) for treatment of high-risk Philadelphia chromosome–positive (Ph+) leukemia…”
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5
Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model
Published in Blood (26-03-2015)“…α-Emitting radionuclides deposit a large amount of energy within a few cell diameters and may be particularly effective for radioimmunotherapy targeting…”
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6
High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study
Published in Blood (15-08-2007)“…More effective therapeutic strategies are required for patients with poor-prognosis systemic sclerosis (SSc). A phase 2 single-arm study of high-dose…”
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7
The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation
Published in Blood (15-12-2007)“…Hematopoietic cell transplantation (HCT) from an HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 allele–matched unrelated donor is a well-recognized life-saving…”
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8
MHC-resident variation affects risks after unrelated donor hematopoietic cell transplantation
Published in Science translational medicine (25-07-2012)“…Blood malignancies can be cured with hematopoietic cell transplantation from human leukocyte antigen (HLA)-matched unrelated donors; however, acute…”
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9
Generation of T-Cell Immunity to the HER-2/neu Protein After Active Immunization With HER-2/neu Peptide–Based Vaccines
Published in Journal of clinical oncology (01-06-2002)“…The HER-2/neu protein is a nonmutated tumor antigen that is overexpressed in a variety of human malignancies, including breast and ovarian cancer. Many tumor…”
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10
Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants
Published in Blood (01-01-2004)“…Male recipients of transplants from female (F→M) hematopoietic stem cell donors represent a special group in whom donor T cells that are specific for recipient…”
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11
CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
Published in The Journal of clinical investigation (01-06-2016)“…T cells that have been modified to express a CD19-specific chimeric antigen receptor (CAR) have antitumor activity in B cell malignancies; however,…”
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12
A comparative analysis of conventional and pretargeted radioimmunotherapy of B-cell lymphomas by targeting CD20, CD22, and HLA-DR singly and in combinations
Published in Blood (14-05-2009)“…Relapsed B-cell lymphomas are currently incurable with conventional chemotherapy and radiation treatments. Radiolabeled antibodies directed against B-cell…”
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13
High-dose radioimmunotherapy versus conventional high-dose therapy and autologous hematopoietic stem cell transplantation for relapsed follicular non-Hodgkin lymphoma: a multivariable cohort analysis
Published in Blood (01-10-2003)“…We performed a multivariable comparison of 125 consecutive patients with follicular lymphoma (FL) treated at our centers with either high-dose…”
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14
Ablative Allogeneic Hematopoietic Cell Transplantation in Adults 60 Years of Age and Older
Published in Journal of clinical oncology (20-05-2005)“…To evaluate outcomes of ablative allogeneic hematopoietic cell transplantation (HCT) in older patients with hematologic malignancies. We treated 52 patients…”
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15
HbA1c and Glucose Management Indicator Discordance: A Real-World Analysis
Published in Diabetes technology & therapeutics (01-04-2021)“…There can be marked discordance between laboratory and estimated (using the glucose management indicator [GMI]) glycated hemoglobin (HbA1c) from continuous…”
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16
Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques
Published in PloS one (13-02-2013)“…The adoptive transfer of antigen-specific effector T cells is being used to treat human infections and malignancy. T cell persistence is a prerequisite for…”
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17
High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes
Published in Blood (01-09-2002)“…Systemic sclerosis (SSc) is a multisystem disease of presumed autoimmune pathogenesis for which no proven effective treatment exists. High-dose…”
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18
Pharmacodynamics of mycophenolate mofetil after nonmyeloablative conditioning and unrelated donor hematopoietic cell transplantation
Published in Blood (15-12-2005)“…The immunosuppressive drug mycophenolate mofetil (MMF) is used after nonmyeloablative hematopoietic cell transplantation (HCT); however, limited…”
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Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease
Published in Journal of clinical oncology (10-04-2022)“…Graft-versus-host disease (GVHD) causes morbidity and mortality following allogeneic hematopoietic cell transplantation. Naive T cells (T ) cause severe GVHD…”
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20
Immunization of Cancer Patients with HER-2/neu-Derived Peptides Demonstrating High-Affinity Binding to Multiple Class II Alleles
Published in Clinical cancer research (15-11-2003)“…Purpose: The purpose of this study was to immunize patients with HER-2/ neu -overexpressing cancer with a multipeptide vaccine comprised of four class II…”
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