Search Results - "GOODRICH, Raymond P"

Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: the African Investigation of the Mirasol System (AIMS) randomised controlled trial by Allain, Jean-Pierre, Prof, Owusu-Ofori, Alex K, MD, Assennato, Sonny Michael, MSc, Marschner, Susanne, PhD, Goodrich, Raymond P, PhD, Owusu-Ofori, Shirley, MD

“…Summary Background Transfusion-transmitted malaria is a frequent but neglected adverse event in Ghana. We did a randomised controlled clinical trial to assess…”
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Pathogen reduction of monkeypox virus in plasma and whole blood using riboflavin and UV light by Ragan, Izabela K, Hartson, Lindsay M, Sullivan, Elizabeth J, Bowen, Richard A, Goodrich, Raymond P

“…Monkeypox virus has recently emerged from endemic foci in Africa and, since October 20, 2022, more than 73,000 human infections have been reported by the CDC…”
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Emerging Pathogen Threats in Transfusion Medicine: Improving Safety and Confidence with Pathogen Reduction Technologies by Cardoso, Marcia, Ragan, Izabela, Hartson, Lindsay, Goodrich, Raymond P

“…Emerging infectious disease threats are becoming more frequent due to various social, political, and geographical pressures, including increased human-animal…”
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Primary hemostatic capacity of whole blood: a comprehensive analysis of pathogen reduction and refrigeration effects over time by Pidcoke, Heather F., McFaul, Steve J., Ramasubramanian, Anand K., Parida, Bijaya K., Mora, Alex G., Fedyk, Chriselda G., Valdez-Delgado, Krystal K., Montgomery, Robbie K., Reddoch, Kristin M., Rodriguez, Armando C., Aden, James K., Jones, John A., Bryant, Ron S., Scherer, Michael R., Reddy, Heather L., Goodrich, Raymond P., Cap, Andrew P.

“…Background Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy…”
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Pilot Acute Safety Evaluation of Innocell™ Cancer Immunotherapy in Canine Subjects by Griffin, Lynn, Hartson, Lindsay, Weston, Jon, Goodrich, Raymond P., Guth, Amanda

“…Background. We are developing cancer immunotherapy based on the use of autologous tumor tissue that has been rendered replication-incompetent but maintains…”
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In memoriam: Dr. Dirk de Korte: June 10, 1955 to March 22, 2024 by Goodrich, Raymond P

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Photochemical inactivation of chikungunya virus in plasma and platelets using the Mirasol pathogen reduction technology system by Vanlandingham, Dana L., Keil, Shawn D., Horne, Kate McElroy, Pyles, Richard, Goodrich, Raymond P., Higgs, Stephen

“…BACKGROUND: Chikungunya virus (CHIKV) is a reemerging mosquito‐borne virus that has been responsible for a number of large‐scale epidemics as well as imported…”
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A Whole Virion Vaccine for COVID-19 Produced via a Novel Inactivation Method and Preliminary Demonstration of Efficacy in an Animal Challenge Model by Ragan, Izabela K, Hartson, Lindsay M, Dutt, Taru S, Obregon-Henao, Andres, Maison, Rachel M, Gordy, Paul, Fox, Amy, Karger, Burton R, Cross, Shaun T, Kapuscinski, Marylee L, Cooper, Sarah K, Podell, Brendan K, Stenglein, Mark D, Bowen, Richard A, Henao-Tamayo, Marcela, Goodrich, Raymond P

“…The COVID-19 pandemic has generated intense interest in the rapid development and evaluation of vaccine candidates for this disease and other emerging…”
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Red Blood Cells Derived from Whole Blood Treated with Riboflavin and UV Light Maintain Adequate Cell Quality through 21 Days of Storage by Dimberg, Lina Y., Doane, Suzann K., Yonemura, Susan, Reddy, Heather L., Hovenga, Nick, Gosney, E. Jane, Tran, Melissa , Wilkinson, Shilo, Goodrich, Raymond P., Marschner, Susanne

“…Background: The Mirasol system for whole blood (WB) is a non-toxic, non-mutagenic pathogen reduction technology (PRT) that treats WB units with riboflavin…”
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Riboflavin and UV-Light Based Pathogen Reduction: Extent and Consequence of DNA Damage at the Molecular Level by Kumar, Vijay, Lockerbie, Owen, Keil, Shawn D., Ruane, Patrick H., Platz, Matthew S., Martin, Christopher B., Ravanat, Jean-Luc, Cadet, Jean, Goodrich, Raymond P.

“…We are developing a technology based on the combined application of riboflavin (RB) and light for inactivating pathogens in blood products while retaining the…”
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Ignorance is not bliss by Goodrich, Raymond P.

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Chemical and Biological Mechanisms of Pathogen Reduction Technologies by Mundt, Janna M., Rouse, Lindsay, Van den Bossche, Jeroen, Goodrich, Raymond P.

“…Within the last decade new technologies have been developed and implemented which employ light, often in the presence of a photosensitizer, to inactivate…”
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Special considerations for the use of pathogen reduced blood components in pediatric patients: An overview by Goodrich, Raymond P., Segatchian, Jerard

“…Pediatric patients requiring transfusion constitute one of the most challenging areas of transfusion practice. Due to the limitations posed by their particular…”
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Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial by van der Meer, Pieter F., Ypma, Paula F., van Geloven, Nan, van Hilten, Joost A., van Wordragen-Vlaswinkel, Rinie J., Eissen, Okke, Zwaginga, Jaap J., Trus, Michael, Beckers, Erik A.M., te Boekhorst, Peter, Tinmouth, Alan, Lin, Yulia, Hsia, Cyrus, Lee, David, Norris, Philip J., Goodrich, Raymond P., Brand, Anneke, Hervig, Tor, Heddle, Nancy M., van der Bom, Johanna G., Kerkhoffs, Jean-Louis H.

“…Pathogen inactivation of platelet concentrates reduces the risk for blood-borne infections. However, its effect on platelet function and hemostatic efficacy of…”
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Releasates of riboflavin/UV‐treated platelets: Microvesicles suppress cytokine‐mediated endothelial cell migration/proliferation by Schubert, Peter, Culibrk, Luka, Culibrk, Brankica, Conway, Edward M., Goodrich, Raymond P., Devine, Dana V.

“…Background Accelerated development of the platelet (PLT) storage lesion upon pathogen inactivation (PI) is associated with the release of proteins from…”
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Inactivation of viruses in platelet and plasma products using a riboflavin-and-UV-based photochemical treatment by Keil, Shawn D., Bengrine, Abderrahmane, Bowen, Richard, Marschner, Susanne, Hovenga, Nick, Rouse, Lindsay, Gilmour, Denise, Duverlie, Gilles, Goodrich, Raymond P.

“…BACKGROUND Multilayered blood safety programs reduce the risk of transfusion‐transmitted diseases; however, there remains a risk of window period transmission…”
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Red blood cells derived from whole blood treated with riboflavin and ultraviolet light maintain adequate survival in vivo after 21 days of storage by Cancelas, Jose A., Slichter, Sherrill J., Rugg, Neeta, Pratt, P. Gayle, Nestheide, Shawnagay, Corson, Jill, Pellham, Esther, Huntington, Marty, Goodrich, Raymond P.

“…BACKGROUND Pathogen reduction (PR) of whole blood (WB) may increase blood safety when applied before component separation. This study evaluates the in vivo…”
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Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment by Schubert, Peter, Coupland, Danielle, Culibrk, Brankica, Goodrich, Raymond P., Devine, Dana V.

“…Background Pathogen reduction technologies (PRTs) significantly reduce the risk of transmission of infectious agents in platelet (PLT) concentrates; however,…”
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Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood by Schubert, Peter, Culibrk, Brankica, Chen, Deborah, Serrano, Katherine, Levin, Elena, Chen, Zhongming, Zoescher, Peter, Goodrich, Raymond P., Yoshida, Tatsuro, Devine, Dana V.

“…BACKGROUND The application of riboflavin/UV‐based pathogen inactivation (PI) to whole blood (WB) is currently limited by its negative impact on red blood cell…”
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Reflections on the dynamics of bacterial and viral contamination of blood components and the levels of efficacy for pathogen inactivation processes by Bah, Aicha, Cardoso, Marcia, Seghatchian, Jerard, Goodrich, Raymond P.

“…Blood transfusion safety has been increasingly improving during the past two decades. However, threats from both known and emerging pathogens require continual…”
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