Search Results - "GOODIN, D. S"
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Incidental MRI anomalies suggestive of multiple sclerosis : The radiologically isolated syndrome
Published in Neurology (03-03-2009)“…The discovery and broad application of MRI in medicine has led to an increased awareness in the number of patients with incidental white matter pathology in…”
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Survival in MS: A randomized cohort study 21 years after the start of the pivotal IFNβ-1b trial
Published in Neurology (24-04-2012)“…To examine the effects of interferon beta (IFNβ)-1b on all-cause mortality over 21 years in the cohort of 372 patients who participated in the pivotal…”
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Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome
Published in Neurology (22-02-2011)“…Technological advancements in neuroimaging and the increased use of these diagnostic modalities are responsible for the discovery of incidentally identified…”
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Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions
Published in BMC medical genomics (10-07-2021)“…To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes (CEHs) of the MHC and three non-MHC…”
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Analysis of clinical outcomes according to original treatment groups 16 years after the pivotal IFNB-1b trial
Published in Journal of neurology, neurosurgery and psychiatry (01-08-2010)“…BackgroundEvidence for efficacy of disease-modifying drugs in multiple sclerosis (MS) comes from trials of short duration. We report results from a 16 y,…”
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Treatment of early multiple sclerosis: the value of treatment initiation after a first clinical episode
Published in Multiple sclerosis (01-10-2009)“…Multiple sclerosis is a chronic, demyelinating disorder of the central nervous system. It is characterised by progressive neurological disability, which is…”
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Evidence-based guideline update: Intraoperative spinal monitoring with somatosensory and transcranial electrical motor evoked potentials: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Clinical Neurophysiology Society
Published in Neurology (21-02-2012)“…To evaluate whether spinal cord intraoperative monitoring (IOM) with somatosensory and transcranial electrical motor evoked potentials (EPs) predicts adverse…”
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Assessment : The use of natalizumab (Tysabri) for the treatment of multiple sclerosis (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Published in Neurology (02-09-2008)“…The clinical and radiologic impact of natalizumab (Tysabri) as therapy for multiple sclerosis (MS) is assessed. On the basis of Class I evidence, natalizumab…”
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Assessment: Transcranial Doppler ultrasonography: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Published in Neurology (11-05-2004)“…To review the use of transcranial Doppler ultrasonography (TCD) and transcranial color-coded sonography (TCCS) for diagnosis. The authors searched the…”
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Neutralizing antibodies to interferon beta: Assessment of their clinical and radiographic impact: An evidence : Report report of the therapeutics and technology assessment subcommittee of the american academy of neurology
Published in Neurology (27-03-2007)“…The clinical and radiologic impact of developing neutralizing antibodies (NAbs) to interferon beta (IFNbeta) while on this therapy for multiple sclerosis (MS)…”
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Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis
Published in Neurology (14-12-2004)“…African American (AA) individuals are thought to develop multiple sclerosis (MS) less frequently than Caucasian American (CA) individuals. To compare the…”
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HLA-DR2 Dose Effect on Susceptibility to Multiple Sclerosis and Influence on Disease Course
Published in American journal of human genetics (01-03-2003)“…Models of disease susceptibility in multiple sclerosis (MS) often assume a dominant action for the HLA-DRB1*1501 allele and its associated haplotype (…”
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Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures
Published in Neurology (19-05-2009)“…Health-related quality of life (HRQOL) is reduced in multiple sclerosis (MS). It is unclear whether HRQOL is associated with white matter lesion burden or…”
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The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Published in Neurology (25-11-2003)“…Mitoxantrone is the first drug approved for the treatment of secondary progressive multiple sclerosis (SPMS) in the United States. This assessment considers…”
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The utility of MRI in suspected MS: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Published in Neurology (09-09-2003)“…Advancements in imaging technologies and newly evolving treatments offer the promise of more effective management strategies for MS. Until recently,…”
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Clinical utility of surface EMG: Report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology
Published in Neurology (25-07-2000)Get full text
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The epidemiology of multiple sclerosis: insights to a causal cascade
Published in Handbook of clinical neurology (2016)“…MS-pathogenesis involves both genetic-susceptibility and environmental determinants. Three (or more) sequential environmental-factors are implicated. The first…”
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Side effect profile of interferon beta-1b in MS : Results of an open label trial
Published in Neurology (01-02-1996)“…To determine which patients are prone to side effects from interferon beta-1b and which side effects are most troublesome, we studied 72 patients with…”
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