Search Results - "GONZALEZ DE REQUENA, Daniel"
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Prediction of virological response to lopinavir/ritonavir using the genotypic inhibitory quotient
Published in AIDS research and human retroviruses (01-03-2004)“…The predictive value of virological response to lopinavir (LPV)/ritonavir (r) was assessed in 126 HIV-infected patients who failed antiretroviral therapy and…”
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Negative Predictive Value of IL28B, SLC28A2, and CYP27B1 SNPs and Low RBV Plasma Exposure for Therapeutic Response to PEG/IFN-RBV Treatment
Published in Therapeutic drug monitoring (01-12-2012)“…The response rate to treatment of chronic hepatitis C virus-genotype 1 and 4 infections was recently found to be strongly influenced by many polymorphisms. The…”
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An improved HPLC fluorimetric method for the determination of enfuvirtide plasma levels in HIV-infected patients
Published in Therapeutic drug monitoring (01-02-2006)“…An improved HPLC fluorimetric method for the quantification of enfuvirtide in plasma of HIV-infected subjects was described and validated. The use of an…”
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Analyzing Sleep Abnormalities in HIV-Infected Patients Treated with Efavirenz
Published in Clinical infectious diseases (01-02-2004)“…Ambulatory electroencephalogram monitoring was performed for 18 HIV-infected subjects treated with efavirenz with and without insomnia and for 13 healthy…”
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Ultrasensitive assessment of residual HIV viraemia in HAART-treated patients with persistently undetectable plasma HIV-RNA: A cross-sectional evaluation
Published in Journal of medical virology (01-03-2009)“…Improvements in HIV-RNA assays have made accurate detection of as few as 2 copies/ml possible. This study objective was the evaluation of ultrasensitive…”
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Validation of liquid/liquid extraction method coupled with HPLC-UV for measurement of ribavirin plasma levels in HCV-positive patients
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-05-2006)“…Measurement of ribavirin plasma levels in HCV-positive patients have been shown to be useful in order to optimise individual ribavirin exposure. Efficacy and…”
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Inosine Triphosphatase Polymorphisms and Ribavirin Pharmacokinetics as Determinants of Ribavirin-Associate Anemia in Patients Receiving Standard Anti-HCV Treatment
Published in Therapeutic drug monitoring (01-04-2012)“…Functional variants of inosine triphosphatase (ITPA) were recently found to protect against ribavirin (RBV)-induced hemolytic anemia. However, no definitive…”
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Raltegravir Penetration in Seminal Plasma of Healthy Volunteers
Published in Antimicrobial agents and chemotherapy (01-06-2010)Get full text
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Impact of drug levels and baseline genotype and phenotype on the virologic response to amprenavir/ritonavir-based salvage regimens
Published in AIDS patient care and STDs (01-01-2004)“…Coadministration of amprenavir (APV) with small doses of ritonavir (RTV) results in a significant increase in APV plasma concentrations. Viruses showing…”
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Pharmacokinetics of the raltegravir/maraviroc/etravirine combination
Published in Journal of antimicrobial chemotherapy (01-08-2011)Get full text
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Comparative evaluation of seven resistance interpretation algorithms and their derived genotypic inhibitory quotients for the prediction of 48 week virological response to darunavir-based salvage regimens
Published in Journal of antimicrobial chemotherapy (2011)“…the darunavir genotypic inhibitory quotient (gIQ) has been suggested as one of the predictors of virological response to darunavir-containing salvage regimens…”
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Pharmacokinetics of switching unboosted atazanavir coadministered with tenofovir disoproxil fumarate from 400 mg once daily to 200 mg twice daily in HIV-positive patients
Published in Antiviral therapy (01-01-2011)“…Use of unboosted atazanavir (ATV) with tenofovir disoproxil fumarate (TDF), although attractive from a clinical view point, has not been tested in trials and…”
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A New Assay Based on Solid-Phase Extraction Procedure with LC-MS to Measure Plasmatic Concentrations of Tenofovir and Emtricitabine in HIV Infected Patients
Published in Journal of chromatographic science (01-07-2008)“…A new solid-phase extraction (SPE) method has been developed and validated on a liquid chromatography (LC) coupled with a mass spectrometer for the…”
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Unexpected drug-drug interaction between tipranavir/ritonavir and enfuvirtide
Published in AIDS (London) (03-10-2006)“…Fifty-five patients placed on tipranavir/ritonavir 500/200 mg twice a day (27 with enfuvirtide and 28 without) underwent tipranavir and ritonavir plasma…”
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Tipranavir (TPV) Genotypic Inhibitory Quotient Predicts Virological Response at 48 Weeks to TPV-Based Salvage Regimens
Published in Antimicrobial Agents and Chemotherapy (01-03-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Liver toxicity caused by nevirapine
Published in AIDS (London) (25-01-2002)“…Nevirapine plasma levels were measured in 70 HIV-infected patients, 33 of whom developed transaminase elevations. Higher nevirapine levels and hepatitis C…”
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Correlation between lopinavir plasma levels and lipid abnormalities in patients taking lopinavir/ritonavir
Published in AIDS patient care and STDs (01-09-2003)“…Lopinavir (LPV)/ritonavir (RTV) used in combination, is a potent antiretroviral drug. However, its benefit is limited by its inherent effect on lipid…”
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A simple and sensitive assay for determining plasma tipranavir concentration in the clinical setting by new HPLC method
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-04-2007)“…A simple method for the quantification of tipranavir, the first non-peptidic HIV protease inhibitor, was developed and validated. Quinoxaline, as internal…”
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Does Iatrogenic Scleroderma due to Injection-Site Reaction to Enfuvirtide Impair Absorption of the Drug?
Published in Clinical drug investigation (01-01-2008)“…Background: Chronic iatrogenic scleroderma is a possible obstacle to the absorption of subcutaneously administered drugs. This study correlated the clinical…”
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