Search Results - "GONZALEZ, Fernando A"

Soluble antigen arrays provide increased efficacy and safety over free peptides for tolerogenic immunotherapy by Firdessa-Fite, Rebuma, Johnson, Stephanie N, Bechi Genzano, Camillo, Leon, Martin A, Ku, Amy, Ocampo Gonzalez, Fernando A, Milner, Joshua D, Sestak, Joshua O, Berkland, Cory, Creusot, Remi J

“…Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat autoimmune diseases, but clinical implementation has been…”
Get full text

Well-differentiated liposarcoma primary from thymic stroma: Case report and literature review by Furlan, Karina, Miller, Ira, Rohra, Prih, Mir, Fatima, Ocampo Gonzalez, Fernando A., Gattuso, Paolo

“…Primary liposarcoma of thymic stroma is an exceptionally rare tumor. Histological findings are often definitive for diagnosis, however due to the variability…”
Get full text

Effect of the Paris system for reporting urinary cytology with histologic follow‐up by Rohra, Prih, Ocampo Gonzalez, Fernando A., Yan, Lei, Mir, Fatima, Furlan, Karina, Basu, Sanjib, Barua, Animesh, Cheng, Lin, Park, Ji‐Weon

“…Background The Paris system (TPS) for Reporting Urinary Cytology provides a standardized reporting system whose main focus is the diagnosis of high‐grade…”
Get full text

Characterization of deletional and non-deletional alpha globin variants in a large cohort from Spain between 2009 and 2014 by de la Fuente-Gonzalo, Félix, Nieto, Jorge M., Villegas, Ana, González, Fernando A., Martínez, Rafael, Ropero, Paloma

“…The hemoglobinopathies are a group of disorders passed down through families (inherited) in which there is abnormal production or structure of the hemoglobin…”
Get full text

Nondeletional α-Thalassemia: Two New Mutations on the α2 Gene by Ropero, Paloma, Arbeteta, Jaime, Nieto, Jorge M., González, Fernando A., González, Beatriz, Villegas, Ana, Benavente, Celina

“…About 10.0% of α-thalassemia (α-thal) cases are due to point mutations, small deletions, or insertions of one or more bases on the α genes that can alter mRNA…”
Get full text

Impact of STAT-signaling pathway on cancer-associated fibroblasts in colorectal cancer and its role in immunosuppression by Sánchez-Ramírez, Damián, Mendoza-Rodríguez, Mónica G, Alemán, Omar R, Candanedo-González, Fernando A, Rodríguez-Sosa, Miriam, Montesinos-Montesinos, Juan José, Salcedo, Mauricio, Brito-Toledo, Ismael, Vaca-Paniagua, Felipe, Terrazas, Luis I

“…Colorectal cancer (CRC) remains one of the most commonly diagnosed and deadliest types of cancer worldwide. CRC displays a desmoplastic reaction (DR) that has…”
Get full text

Development and validation of a multivariable prediction rule for detecting a severe acquired ADAMTS13 activity deficiency in patients with thrombotic microangiopathies by Nieto, Jorge M, De La Fuente-Gonzalo, Félix, González, Fernando A, Villegas, Ana, Martínez, Rafael, Fuentes, Manuel E, Ropero, Paloma

“…Thrombotic microangiopathies (TMAs) are a group of diseases that have different aetiologies and treatments, but a clinical differential diagnosis remains…”
Get more information

Hb Cervantes, Hb Marañón, Hb La Mancha and Hb Goya: Description of 4 new haemoglobinopathies by de la Fuente-Gonzalo, Félix, Nieto, Jorge M., Ricard, Pilar, Anguita, Javier, Martínez, Rosalina, Cervera, Aurea, Villegas, Ana, González, Fernando A., Ropero, Paloma

“…α-thalassemias are caused by a deficiency in or absence of synthesis of the α-chain of haemoglobin (Hb). In contrast, structural haemoglobinopathies are due to…”
Get full text

Hemoglobin Le Lamentin in the province of Albacete, Spain: Discovery of 32 cases by Martínez-López, Rosalina, Ropero, Paloma, Ballesteros Gallar, Cristina, Romero Román, Carlos, de la Fuente-Gonzalo, Félix, M. Nieto, Jorge, Navarro Casado, Laura, González, Fernando A.

“…Hemoglobin Le Lamentin (α20(B1)His→Gln) is a ubiquitous variant that has been previously described in a small number of isolated patients. We report the…”
Get full text

Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia by de la Fuente-Gonzalo, Félix, Nieto, Jorge M., Vinuesa, Lara, Sevilla, Julián, Díaz-Mediavilla, Joaquín, Villegas, Ana, González, Fernando A., Ropero, Paloma

“…Thalassemias are the most frequent monogenic disorders around the world and are a serious health problem in areas with a high incidence. Thalassemias are…”
Get full text

Different forms of Hb Le Lamentin. An unexpected finding in Hba1c quantification by Martínez-López, Rosalina, de la Fuente-Gonzalo, Félix, Nieto, Jorge M., Gallar, Cristina Ballesteros, Román, Carlos Romero, Villegas, Ana, González, Fernando A., Martínez, Rafael, Casado, Laura Navarro, Ropero, Paloma

“…Glycated hemoglobin (HbA1c) is accepted as the most trusted marker for monitoring patients with diabetes mellitus. Ion-exchange high-performance liquid…”
Get full text

Plasmablastic Lymphoma Associated with Adjacent Mature Plasma Cell Population Exhibiting Opposite Light Chain Restriction by Ocampo Gonzalez, Fernando A., Mahon, Brett, Miller, Ira, Furlan, Karina, Ward, Nicholas

“…Plasmablastic lymphoma (PBL) is an aggressive high-grade B cell lymphoma, considered a variant of diffuse large B cell lymphoma with approximately 75%…”
Get full text

P2X7 nucleotide receptor activation enhances IFNγ‐induced type II nitric oxide synthase activity in BV‐2 microglial cells by Gendron, Fernand‐Pierre, Chalimoniuk, Malgorzata, Strosznajder, Joanna, Shen, Siming, González, Fernando A., Weisman, Gary A., Sun, Grace Y.

“…Under normal and pathological conditions, brain cells release nucleotides that regulate a wide range of cellular responses due to activation of P2 nucleotide…”
Get full text

P2Y2 receptors activate neuroprotective mechanisms in astrocytic cells by Chorna, Nataliya E., Santiago‐Pérez, Laura I., Erb, Laurie, Seye, Cheikh I., Neary, Joseph T., Sun, Grace Y., Weisman, Gary A., González, Fernando A.

“…Mechanical or ischemic trauma to the CNS causes the release of nucleotides and other neurotransmitters into the extracellular space. Nucleotides can activate…”
Get full text

Association between hemoglobin Groene Hart and hemoglobin J-Paris-I: First case in Spain by de la Fuente-Gonzalo, Félix, Ropero, Paloma, Martínez-Nieto, Jorge, Villegas, Ana, González, Fernando A., Díaz-Mediavilla, Joaquín

“…Thalassemias are the most frequent monogenic disorder around the world. α-Thalassemias are due to a deficiency of synthesis in the alpha-globin chain of the…”
Get full text

Heterozygosity for deletion of hypersensitive site 3 in the human locus control region has an unexpected minor effect on red cell phenotype by Nieto, Jorge M, Villegas, Ana, De La Fuente-Gonzalo, Felix, González, Fernando A, Ropero, Paloma

“…The locus control region (LCR) is a genetic region that regulates the expression of the β-globin locus (HBB locus). This region is composed of several DNase I…”
Get full text

Functional P2Y2 nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries by SEYE, Cheikh I, QIONGMAN KONG, ERB, Laurie, GARRAD, Richard C, KRUGH, Brent, MEIFANG WANG, TURNER, John T, STUREK, Michael, GONZALEZ, Fernando A, WEISMAN, Gary A

“…Extracellular uridine 5'-triphosphate (UTP) induces mitogenic activation of smooth muscle cells (SMCs) through binding to P2Y2 nucleotide receptors. P2Y2…”
Get full text

Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells by Gendron, Fernand-Pierre, Neary, Joseph T, Theiss, Patty M, Sun, Grace Y, Gonzalez, Fernando A, Weisman, Gary A

“…Astrocytes are involved in normal and pathological brain functions, where they become activated and undergo reactive gliosis. Astrocytes have been shown to…”
Get more information

Identification of Flap Structure-Specific Endonuclease 1 as a Factor Involved in Long-Term Memory Formation of Aversive Learning by Saavedra-Rodriguez, Lorena, Vazquez, Adrinel, Ortiz-Zuazaga, Humberto G, Chorna, Nataliya E, Gonzalez, Fernando A, Andres, Lissette, Rodriguez, Karen, Ramirez, Fernando, Rodriguez, Alan, de Ortiz, Sandra Pena

“…We previously proposed that DNA recombination/repair processes play a role in memory formation. Here, we examined the possible role of the fen-1 gene, encoding…”
Get full text

Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2-a]quinolinium Chloride by Colón, Iris Gisela, González, Fernando A, Cordero, Marisol, Zayas, Beatriz, Velez, Christian, Cox, Osvaldo, Kumar, Ajay, Alegría, Antonio E

“…Interest in DNA binding drugs has increased in recent years due to their importance in the treatment of genome-related diseases, like cancer. A new family of…”
Get full text