Search Results - "GOMIS, RAMON"

Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance by Schneeberger, Marc, Gomis, Ramon, Claret, Marc

“…Alterations in adequate energy balance maintenance result in serious metabolic disturbances such as obesity. In mammals, this complex process is orchestrated…”
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Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice by Schneeberger, Marc, Everard, Amandine, Gómez-Valadés, Alicia G., Matamoros, Sébastien, Ramírez, Sara, Delzenne, Nathalie M., Gomis, Ramon, Claret, Marc, Cani, Patrice D.

“…Recent evidence indicates that the gut microbiota plays a key role in the pathophysiology of obesity. Indeed, diet-induced obesity (DIO) has been associated to…”
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Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells by Fernandez-Ruiz, Rebeca, García-Alamán, Ainhoa, Esteban, Yaiza, Mir-Coll, Joan, Serra-Navarro, Berta, Fontcuberta-PiSunyer, Marta, Broca, Christophe, Armanet, Mathieu, Wojtusciszyn, Anne, Kram, Vardit, Young, Marian F., Vidal, Josep, Gomis, Ramon, Gasa, Rosa

“…Expanding the mass of pancreatic insulin-producing beta cells through re-activation of beta cell replication has been proposed as a therapy to prevent or delay…”
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Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial by Home, Philip D, Prof, Pocock, Stuart J, Prof, Beck-Nielsen, Henning, Prof, Curtis, Paula S, PhD, Gomis, Ramon, Prof, Hanefeld, Markolf, Prof, Jones, Nigel P, MA, Komajda, Michel, Prof, McMurray, John JV, Prof

“…Summary Background Rosiglitazone is an insulin sensitiser used in combination with metformin, a sulfonylurea, or both, for lowering blood glucose in people…”
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Rosiglitazone Evaluated for Cardiovascular Outcomes — An Interim Analysis by Home, Philip D, Pocock, Stuart J, Beck-Nielsen, Henning, Gomis, Ramón, Hanefeld, Markolf, Jones, Nigel P, Komajda, Michel, McMurray, John J.V

“…Meta-analyses suggest that the thiazolidinedione rosiglitazone, used in the treatment of type 2 diabetes, may increase the risk of myocardial infarction and…”
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Altered clock gene expression in obese visceral adipose tissue is associated with metabolic syndrome by Vieira, Elaine, Ruano, Elena g, Figueroa, Ana Lucia C, Aranda, Gloria, Momblan, Dulce, Carmona, Francesc, Gomis, Ramon, Vidal, Josep, Hanzu, Felicia A

“…Clock gene expression was associated with different components of metabolic syndrome (MS) in human adipose tissue. However, no study has been done to compare…”
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Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control by Ramírez, Sara, Gómez-Valadés, Alicia G., Schneeberger, Marc, Varela, Luis, Haddad-Tóvolli, Roberta, Altirriba, Jordi, Noguera, Eduard, Drougard, Anne, Flores-Martínez, Álvaro, Imbernón, Mónica, Chivite, Iñigo, Pozo, Macarena, Vidal-Itriago, Andrés, Garcia, Ainhoa, Cervantes, Sara, Gasa, Rosa, Nogueiras, Ruben, Gama-Pérez, Pau, Garcia-Roves, Pablo M., Cano, David A., Knauf, Claude, Servitja, Joan-Marc, Horvath, Tamas L., Gomis, Ramon, Zorzano, Antonio, Claret, Marc

“…Proopiomelanocortin (POMC) neurons are critical sensors of nutrient availability implicated in energy balance and glucose metabolism control. However, the…”
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Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells by Vieira, Elaine, Marroquí, Laura, Figueroa, Ana Lucia C, Merino, Beatriz, Fernandez-Ruiz, Rebeca, Nadal, Angel, Burris, Thomas P, Gomis, Ramon, Quesada, Ivan

“…Disruption of pancreatic clock genes impairs pancreatic beta-cell function, leading to the onset of diabetes. Despite the importance of pancreatic alpha-cells…”
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Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion by McCluskey, Jane T., Hamid, Muhajir, Guo-Parke, Hong, McClenaghan, Neville H., Gomis, Ramon, Flatt, Peter R.

“…Three novel human insulin-releasing cell lines designated 1.1B4, 1.4E7, and 1.1E7 were generated by electrofusion of freshly isolated of human pancreatic beta…”
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Protein tyrosine phosphatase-1B modulates pancreatic β-cell mass by Fernandez-Ruiz, Rebeca, Vieira, Elaine, Garcia-Roves, Pablo M, Gomis, Ramon

“…Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator of the insulin signalling pathway. It has been demonstrated that PTP1B deletion protects…”
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Twelve- and 52-Week Efficacy of the Dipeptidyl Peptidase IV Inhibitor LAF237 in Metformin-Treated Patients With Type 2 Diabetes by AHREN, Bo, GOMIS, Ramon, STANDL, Eberhard, MILLS, David, SCHWEIZER, Anja

“…Twelve- and 52-Week Efficacy of the Dipeptidyl Peptidase IV Inhibitor LAF237 in Metformin-Treated Patients With Type 2 Diabetes Bo Ahrén , MD 1 , Ramon Gomis ,…”
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Endogenous cortisol excess confers a unique lipid signature and metabolic network by Vega-Beyhart, Arturo, Iruarrizaga, Marta, Pané, Adriana, García-Eguren, Guillermo, Giró, Oriol, Boswell, Laura, Aranda, Gloria, Flores, Vanesa, Casals, Gregori, Alonso, Cristina, Mora, Mireia, Halperin, Irene, Carmona, Francesc, Enseñat, Joaquim, Vidal, Oscar, Hu, Ting, Rojo, Gemma, Gomis, Ramon, Hanzu, Felicia A

“…Chronic cortisol excess induces several alterations on protein, lipid and carbohydrate metabolism resembling those found in the metabolic syndrome. However,…”
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Taurine Treatment Modulates Circadian Rhythms in Mice Fed A High Fat Diet by Figueroa, Ana Lucia C., Figueiredo, Hugo, Rebuffat, Sandra A., Vieira, Elaine, Gomis, Ramon

“…Close ties have been made among certain nutrients, obesity, type 2 diabetes and circadian clocks. Among nutrients, taurine has been documented as being…”
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Glycaemia Fluctuations Improvement in Old-Age Prediabetic Subjects Consuming a Quinoa-Based Diet: A Pilot Study by Díaz-Rizzolo, Diana A, Acar-Denizli, Nihan, Kostov, Belchin, Roura, Elena, Sisó-Almirall, Antoni, Delicado, Pedro, Gomis, Ramon

“…This study aimed to observe if quinoa could produce a benefit on postprandial glycemia that would result in less progression to type 2 diabetes (T2D). A…”
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Effects of sardine-enriched diet on metabolic control, inflammation and gut microbiota in drug-naïve patients with type 2 diabetes: a pilot randomized trial by Balfegó, Mariona, Canivell, Silvia, Hanzu, Felicia A, Sala-Vila, Aleix, Martínez-Medina, Margarita, Murillo, Serafín, Mur, Teresa, Ruano, Elena G, Linares, Francisca, Porras, Nuria, Valladares, Silvia, Fontalba, Maria, Roura, Elena, Novials, Anna, Hernández, Cristina, Aranda, Gloria, Sisó-Almirall, Antoni, Rojo-Martínez, Gemma, Simó, Rafael, Gomis, Ramon

“…Nutrition therapy is the cornerstone of treating diabetes mellitus. The inclusion of fish (particularly oily fish) at least two times per week is recommended…”
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The Mitochondria-Targeted Antioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia by Escribano-Lopez, Irene, Bañuls, Celia, Diaz-Morales, Noelia, Iannantuoni, Francesca, Rovira-Llopis, Susana, Gomis, Ramon, Rocha, Milagros, Hernandez-Mijares, Antonio, Murphy, Michael P, Victor, Victor M

“…Mitochondria-targeted antioxidants such as mitoquinone (MitoQ) have demonstrated protective effects against oxidative damage in several diseases. The increase…”
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Low Physical Activity and Its Association with Diabetes and Other Cardiovascular Risk Factors: A Nationwide, Population-Based Study by Brugnara, Laura, Murillo, Serafín, Novials, Anna, Rojo-Martínez, Gemma, Soriguer, Federico, Goday, Albert, Calle-Pascual, Alfonso, Castaño, Luis, Gaztambide, Sonia, Valdés, Sergio, Franch, Josep, Castell, Conxa, Vendrell, Joan, Casamitjana, Roser, Bosch-Comas, Anna, Bordiú, Elena, Carmena, Rafael, Catalá, Miguel, Delgado, Elias, Girbés, Juan, López-Alba, Alfonso, Martínez-Larrad, Maria Teresa, Menéndez, Edelmiro, Mora-Peces, Inmaculada, Pascual-Manich, Gemma, Serrano-Ríos, Manuel, Gomis, Ramon, Ortega, Emilio

“…Low physical activity (PA), or sedentary lifestyle, is associated with the development of several chronic diseases. We aimed to investigate current prevalence…”
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Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8) by Ejarque, Miriam, Mir-Coll, Joan, Gomis, Ramon, German, Michael S, Lynn, Francis C, Gasa, Rosa

“…Atonal Homolog 8 (Atoh8) is a basic helix-loop-helix (bHLH) transcription factor that is highly conserved across species and expressed in multiple tissues…”
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Characterization of the transcriptional activity of the basic helix–loop–helix (bHLH) transcription factor Atoh8 by Ejarque, Miriam, Altirriba, Jordi, Gomis, Ramon, Gasa, Rosa

“…The atonal-related Neurogenin/NeuroD family of basic helix–loop–helix (bHLH) transcription factors comprises potent inducers of neuronal and endocrine…”
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Melatonin prevents mitochondrial dysfunction and insulin resistance in rat skeletal muscle by Teodoro, Bruno G., Baraldi, Flavia G., Sampaio, Igor H., Bomfim, Lucas H. M., Queiroz, André L., Passos, Madla A., Carneiro, Everardo M., Alberici, Luciane C., Gomis, Ramon, Amaral, Fernanda G., Cipolla-Neto, José, Araújo, Michel B., Lima, Tanes, Akira Uyemura, Sérgio, Silveira, Leonardo R., Vieira, Elaine

“…Melatonin has a number of beneficial metabolic actions and reduced levels of melatonin may contribute to type 2 diabetes. The present study investigated the…”
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