Search Results - "GOLLOB, K. J."

Immunoregulatory networks in human Chagas disease by Dutra, W. O., Menezes, C. A. S., Magalhães, L. M. D., Gollob, K. J.

“…Summary Chagas disease, caused by the infection with Trypanosoma cruzi, is endemic in all Latin America. Due to the increase in population migration, Chagas…”
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Captopril increases the intensity of monocyte infection by Trypanosoma cruzi and induces human T helper type 17 cells by Coelho dos Santos, J.S, Menezes, C.A.S, Villani, F.N.A, Magalhães, L.M.D, Scharfstein, J, Gollob, K.J, Dutra, W.O

“…The anti‐hypertensive drug captopril is used commonly to reduce blood pressure of patients with severe forms of Chagas disease, a cardiomyopathy caused by…”
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Flow Cytometric Determination of Cellular Sources and Frequencies of Key Cytokine-Producing Lymphocytes Directed against Recombinant LACK and Soluble Leishmania Antigen in Human Cutaneous Leishmaniasis by BOTTREL, R. L. A, DUTRA, W. O, GOLLOB, K. J, MARTINS, F. A, GONTIJO, B, CARVALHO, E, BARRAL-NETTO, M, BARRAL, A, ALMEIDA, R. P, MAYRINK, W, LOCKSLEY, R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antigen specific correlations of cellular immune responses in human leishmaniasis suggests mechanisms for immunoregulation by ANTONELLI, L. R. V., DUTRA, W. O., ALMEIDA, R. P., BACELLAR, O., GOLLOB, K. J.

“…SUMMARY Regulation of the immune response directed against Leishmania is critical for the establishment of effective control of the disease. It is likely that…”
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Interleukin‐6 expression and gene polymorphism are associated with severity of periodontal disease in a sample of Brazilian individuals by Moreira, P. R., Lima, P. M. A., Sathler, K. O. B., Imanishi, S. A. W., Costa, J. E., Gomez, R. S., Gollob, K. J., Dutra, W. O.

“…Summary Interleukin (IL)‐6 is an inflammatory mediator involved in bone resorption. G/C polymorphism at position −174 of the IL‐6 gene has been reported to…”
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CD4+ T cells defined by their Vβ T cell receptor expression are associated with immunoregulatory profiles and lesion size in human leishmaniasis by Keesen, T. S. L., Antonelli, L. R. V., Faria, D. R., Guimarães, L. H., Bacellar, O., Carvalho, E. M., Dutra, W. O., Gollob, K. J.

“…Summary Leishmaniasis is caused by infection with the protozoan parasite, Leishmania, that parasitizes human cells, and the cellular immune response is…”
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Phenotypic and functional characteristics of CD28+ and CD28− cells from chagasic patients: distinct repertoire and cytokine expression by MENEZES, C. A. S., ROCHA, M. O. C., SOUZA, P. E. A., CHAVES, A. C. L., GOLLOB, K. J., DUTRA, W. O.

“…SUMMARY Chronic human Chagas’ disease ranges from an asymptomatic to a severe cardiac clinical form. The involvement of the host's immune response in the…”
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Expression of neuronal calcium sensor-1 (NCS-1) is decreased in leukocytes of schizophrenia and bipolar disorder patients by Torres, K.C.L., Souza, B.R., Miranda, D.M., Sampaio, A.M., Nicolato, R., Neves, F.S., Barros, A.G.A., Dutra, W.O., Gollob, K.J., Correa, H., Romano-Silva, M.A.

“…Schizophrenia (SCZ) and bipolar disorder (BPD) are severe illnesses representing an enormous social, familiar and individual burden that affect 1% of the…”
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Association of CD28 and CTLA-4 gene polymorphisms with aggressive periodontitis in Brazilians by e Silva, MRMA, Moreira, PR, da Costa, GC, Saraiva, AM, Souza, PEA de, Amormino, SAF, Costa, JE da, Gollob, KJ, Dutra, WO

“…Objective Susceptibility to and severity of periodontal disease is influenced by gene polymorphisms related to the immune response. Co‐stimulatory molecules,…”
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Immunoregulation in human American leishmaniasis: balancing pathology and protection by Gollob, K. J., Viana, A. G., Dutra, W. O.

“…Summary Leishmaniasis covers a broad spectrum of diseases with distinct, and sometimes overlapping, characteristics. The common thread in all forms of…”
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The IL1A (−889) gene polymorphism is associated with chronic periodontal disease in a sample of Brazilian individuals by Moreira, P. R., Costa, J. E., Gomez, R. S., Gollob, K. J., Dutra, W. O.

“…Background and Objective:  It has been proposed that genotypes reflective of polymorphisms in cytokine genes can predispose individuals to disease by enhancing…”
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Mucosal Leishmaniasis Patients Display an Activated Inflammatory T‐cell Phenotype Associated with a Nonbalanced Monocyte Population by Gaze, S. T., Dutra, W. O., Lessa, M., Lessa, H., Guimarães, L. H., De Jesus, A. R., Carvalho, L. P., Machado, P., Carvalho, E. M., Gollob, K. J.

“…Leishmania braziliensis is a parasite that can induce at least two clinical forms of leishmaniasis in humans: cutaneous leishmaniasis (CL) and mucosal…”
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Lack of interferon γ receptor β chain and the prevention of interferon γ signaling in TH1 cells by PERNIS, A, SANJAY GUPTA, GOLLOB, K. J, GARFEIN, E, COFFMAN, R. L, SCHINDLER, C, ROTHMAN, P

“…The ability of interferon gamma (IFN-gamma) to inhibit the proliferation of type 2 T helper cells (TH2), but not that of type 1 (TH1) cells, suggests that…”
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Specific activation of CD4–CD8– double‐negative T cells by Trypanosoma cruzi‐derived glycolipids induces a proinflammatory profile associated with cardiomyopathy in Chagas patients by Passos, L. S. A., Magalhães, L. M. D., Soares, R. P., Marques, A. F., Nunes, M. do C. P., Gollob, K. J., Dutra, W. O.

“…Summary Cardiomyopathy is the most severe outcome of Chagas disease, causing more than 12 000 deaths/year. Immune cells participate in cardiomyopathy…”
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TNFA and IL10 gene polymorphisms are not associated with periodontitis in Brazilians by Moreira, P R, Costa, J E, Gomez, R S, Gollob, K J, Dutra, W O

“…IL-10 and TNF-α are cytokines that have complex and opposing roles in the inflammatory responses. G/A polymorphisms at position -1082 of IL10 and -308 of TNFA…”
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Recruitment of CD8+ T cells expressing granzyme A is associated with lesion progression in human cutaneous leishmaniasis by FARIA, D. R., SOUZA, P. E. A., DURÃES, F. V., CARVALHO, E. M., GOLLOB, K. J., MACHADO, P. R., DUTRA, W. O.

“…Summary Human infection with Leishmania braziliensis leads to the establishment of cutaneous leishmaniasis (CL), characterized by the appearance of skin…”
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Effect of LACK and KMP11 on IFN‐γ Production by Peripheral Blood Mononuclear Cells from Cutaneous and Mucosal Leishmaniasis Patients by Carvalho, L. P., Passos, S., Dutra, W. O., Soto, M., Alonso, C., Gollob, K. J., Carvalho, E. M., Ribeiro de Jesus, A.

“…The immune modulatory properties of recombinant antigens Kinetoplasmid membrane protein‐11 (KMP11) and Leishmania homologue of receptors for activated C kinase…”
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Immunochemotherapy in American cutaneous leishmaniasis: immunological aspects before and after treatment by Toledo, V P, Mayrink, W, Gollob, K J, Oliveira, M A, Costa, C A, Genaro, O, Pinto, J A, Afonso, L C

“…In this study, we evaluated the immune response of patients suffering from cutaneous leishmaniasis treated with two distinct protocols. One group was treated…”
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A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL-4-secreting cells by Gollob, KJ, Coffman, RL

“…The culture of CD4+ T cells with immobilized anti-CD3 and IL-2 generated a population of cells that produced both IL-4 and IFN-gamma on restimulation. In…”
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Role of transforming growth factor-beta in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B by Nagelkerken, L, Gollob, K J, Tielemans, M, Coffman, R L

“…Stimulation of murine CD4+ T cells with staphylococcal enterotoxin B (SEB) results in the preferential development of T helper (Th) 1 cells [i.e. high…”
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