Search Results - "GOLDMANN, T"

PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C by Goldmann, T, Overlack, N, Wolfrum, U, Nagel-Wolfrum, K

“…We investigated the therapeutic potential of the premature termination codon (PTC) readthrough-inducing drug PTC124 in treating the retinal phenotype of Usher…”
Get more information

PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy by Goldmann, T., Kugler, C., Reinmuth, N., Vollmer, E., Reck, M.

“…We show copy number gain in of the PD-L1 gene about 5% NSCLC. This seems to be associated with low differntiation and high expression of the protein. Patiens…”
Get full text

Glioma infiltration of the corpus callosum: early signs detected by DTI by Kallenberg, K., Goldmann, T., Menke, J., Strik, H., Bock, H. C., Stockhammer, F., Buhk, J. H., Frahm, J., Dechent, P., Knauth, M.

“…The most frequent primary brain tumors, anaplastic astrocytomas (AA) and glioblastomas (GBM): tend to invasion of the surrounding brain. Histopathological…”
Get full text

Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation? by Watermann, I, Schmitt, B, Stellmacher, F, Müller, J, Gaber, R, Kugler, Ch, Reinmuth, N, Huber, R M, Thomas, M, Zabel, P, Rabe, K F, Jonigk, D, Warth, A, Vollmer, E, Reck, M, Goldmann, T

“…Several c-MET targeting inhibitory molecules have already shown promising results in the treatment of patients with Non-small Cell Lung Cancer (NSCLC)…”
Get full text

Meat allergy associated with galactosyl‐α‐(1,3)‐galactose (α‐Gal)—Closing diagnostic gaps by anti‐α‐Gal IgE immune profiling by Jappe, U., Minge, S., Kreft, B., Ludwig, A., Przybilla, B., Walker, A., Varga, R., Seidel, P., Biedermann, T., Anemüller, W., Kromminga, A., Ruëff, F., Merk, H., Wagner, N., Treudler, R., Worm, M., Waldmann, I., Saloga, J., Becker, W. M., Goldmann, T., Platts‐Mills, T. A., Homann, A.

“…Background Glycoproteins and glycolipids of some mammalian species contain the disaccharide galactosyl‐α‐(1,3)‐galactose (α‐Gal). It is known that α‐Gal is…”
Get full text

A Vicious Circle of Alveolar Macrophages and Fibroblasts Perpetuates Pulmonary Fibrosis via CCL18 by Prasse, Antje, Pechkovsky, Dmitri V, Toews, Galen B, Jungraithmayr, Wolfgang, Kollert, Florian, Goldmann, Torsten, Vollmer, Ekkehard, Muller-Quernheim, Joachim, Zissel, Gernot

“…Recently, models of macrophage activation have been revised. Macrophages stimulated with Th2 cytokines have been classified as alternatively activated. This…”
Get full text

Effects of Antimicrobial Peptides on Methanogenic Archaea by BANG, C, SCHILHABEL, A, WEIDENBACH, K, KOPP, A, GOLDMANN, T, GUTSMANN, T, SCHMITZ, R. A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer by Esendagli, G, Bruderek, K, Goldmann, T, Busche, A, Branscheid, D, Vollmer, E, Brandau, S

“…Summary Even though the lung represents a special immune compartment with the capacity of a high inflammatory response, ineffective anti-tumour immunity is…”
Get full text

Kinematics of human spine during hippotherapy by Goldmann, T., Vilimek, M.

Get full text

Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease by Heinbockel, Lena, Marwitz, Sebastian, Schromm, Andra B, Watz, Henrik, Kugler, Christian, Ammerpohl, Ole, Schnepf, Karoline, Rabe, Klaus F, Droemann, Daniel, Goldmann, Torsten

“…As part of a study aimed at illuminating at least some of the complex molecular events taking place in COPD, we screened tissues by means of transcriptome…”
Get full text

Optimized immunohistochemistry in combination with image analysis: A reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer by Lang, D.S, Heilenkötter, U, Schumm, W, Behrens, O, Simon, R, Vollmer, E, Goldmann, T

“…Abstract The determination of the invasion markers urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1) has further…”
Get full text

Transforming Growth Factor-Beta Signaling Leads to uPA/PAI-1 Activation and Metastasis: A Study on Human Breast Cancer Tissues by Lang, D. S., Marwitz, S., Heilenkötter, U., Schumm, W., Behrens, O., Simon, R., Reck, M., Vollmer, E., Goldmann, T.

“…Metastasis represents a major problem in the treatment of patients with advanced primary breast cancer. Both Transforming Growth Factor-Beta (TGF-β) signaling…”
Get full text

Alveolar macrophages are the main source for tumour necrosis factor-α in patients with sarcoidosis by FEHRENBACH, H, ZISSEL, G, GOLDMANN, T, TSCHERNIG, T, VOLLMER, E, PABST, R, MÜLLER-QUERNHEIM, J

“…Tumour necrosis factor (TNF)-alpha is known to play a major role in the formation of noncaseating granuloma, a hallmark of sarcoidosis. The main cellular…”
Get full text

Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs by Schramm, G., Hamilton, J.V., Balog, C.I.A., Wuhrer, M., Gronow, A., Beckmann, S., Wippersteg, V., Grevelding, C.G., Goldmann, T., Weber, E., Brattig, N.W., Deelder, A.M., Dunne, D.W., Hokke, C.H., Haas, H., Doenhoff, M.J.

“…The major immunopathological consequences of infection with Schistosoma mansoni, a T helper type 2 response and granuloma formation leading to fibrotic tissue…”
Get full text

Pulmonary haptoglobin and CD163 are functional immunoregulatory elements in the human lung by Abdullah, M, Kähler, D, Vock, C, Reiling, N, Kugler, C, Drömann, D, Rupp, J, Hauber, H P, Fehrenbach, H, Zabel, P, Vollmer, E, Dalhoff, K, Goldmann, T

“…The acute-phase protein haptoglobin (Hp) and its receptor CD163 serve as immunomodulators and possess anti-inflammatory besides antioxidant functions. To…”
Get more information

Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung by Schultz, H, Marwitz, S, Baron-Lühr, B, Zissel, G, Kugler, C, Rabe, K F, Zabel, P, Vollmer, E, Gerdes, J, Goldmann, T

“…Background: Different therapy regimens in non-small-cell lung cancer (NSCLC) are of rising clinical importance, and therefore a clear-cut subdifferentiation is…”
Get full text

Ventilation-induced activation of the mitogen-activated protein kinase pathway by Uhlig, U, Haitsma, J.J, Goldmann, T, Poelma, D.L, Lachmann, B, Uhlig, S

“…Mechanical ventilation of patients can be a life-saving treatment, but also imposes additional stress on the lung. Mitogen-activated protein kinases (MAPK)…”
Get full text

MASTICATORY FORCE MEASUREMENT IN NATURAL DENTITION by Himmlova, L, Goldmann, T, Konvickova, S

Get full text

Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II by Pechkovsky, D V, Zissel, G, Goldmann, T, Einhaus, M, Taube, C, Magnussen, H, Schlaak, M, Müller-Quernheim, J

“…The human alveolar type II epithelium-like cell line A549 expresses nitric oxide synthase type 2 (NOS2), but not NOS3, and produces nitric oxide (NO) upon…”
Get more information

Pulmonary haptoglobin: a new marker for adenocarcinomas of the lung? by Abdullah, M., Marwitz, S., Kähler, D., Schultz, H., Kugler, C., Zabel, P., Vollmer, E., Goldmann, T.

Get full text