Search Results - "GOLDMAN, C. K"
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Vascular endothelial growth factor in human glioma cell lines : induced secretion by EGF, PDGF-BB, and bFGF
Published in Journal of neurosurgery (01-05-1995)“…Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) is an endothelial cell-specific mitogen that is structurally related to…”
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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells : a model of glioblastoma multiforme pathophysiology
Published in Molecular biology of the cell (1993)“…Hypervascularity, focal necrosis, persistent cerebral edema, and rapid cellular proliferation are key histopathologic features of glioblastoma multiforme…”
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Demonstration of a Non-Tac Peptide that Binds Interleukin 2: A Potential Participant in a Multichain Interleukin 2 Receptor Complex
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1986)“…The interleukin 2 (IL-2) receptor system plays a key role in the T-cell immune response. Although IL-2 binding was reported to be restricted to the Tac…”
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The Interleukin (IL) 2 Receptor β Chain is Shared by IL-2 and a Cytokine, Provisionally Designated IL-T, That Stimulates T-Cell Proliferation and the Induction of Lymphokine-Activated Killer Cells
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-1994)“…Late-phase human T-cell lymphotropic virus I-associated adult T-cell leukemia cells express IL-2 receptors (IL-2R) but no longer produce IL-2. We have reported…”
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A Lymphokine, Provisionally Designated Interleukin T and Produced by a Human Adult T-Cell Leukemia Line, Stimulates T-Cell Proliferation and the Induction of Lymphokine-Activated Killer Cells
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-1994)“…In early phases of human T-cell lymphotropic virus I-induced adult T-cell leukemia (ATL), the malignant cell proliferation is associated with an autocrine…”
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Brain edema in meningiomas is associated with increased vascular endothelial growth factor expression
Published in Neurosurgery (01-06-1997)“…Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF), an endothelial cell-specific cytokine, induces proliferation of endothelial cells…”
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Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor
Published in Cancer research (Chicago, Ill.) (15-04-1997)“…Kaposi's sarcoma (KS) is a major AIDS-related malignancy associated with significant morbidity and mortality. Current chemotherapeutic regimens are associated…”
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Radioimmunotherapy of Interleukin-2Rα-Expressing Adult T-Cell Leukemia With Yttrium-90–Labeled Anti-Tac
Published in Blood (01-12-1995)“…Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus human T-cell lymphotropic virus-1. It is an aggressive leukemia with…”
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Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector
Published in Nature biotechnology (01-09-1997)“…Gene therapy to correct defective genes requires efficient gene delivery and long-term gene expression. The available vector systems have not allowed the…”
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In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer
Published in Nature biotechnology (01-05-1997)“…A synthetic polyamino polymer with a glucose backbone was used for gene transfer in vitro and in vivo. Gene transfer in vitro to various human carcinoma cell…”
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Regional angiogenesis with Vascular Endothelial growth factor in peripheral arterial disease: A phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
Published in Circulation (New York, N.Y.) (21-10-2003)“…"Therapeutic angiogenesis" seeks to improve perfusion by the growth of new blood vessels. The Regional Angiogenesis with Vascular Endothelial growth factor…”
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The interleukin-2 receptor : a target for monoclonal antibody treatment of human T-cell lymphotrophic virus I-induced adult T-cell leukemia
Published in Blood (15-09-1993)“…Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus human T-cell lymphotrophic virus-I (HTLV-I). It is an aggressive…”
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APO-1-induced apoptosis of leukemia cells from patients with adult T-cell leukemia
Published in Blood (01-06-1993)“…The 48-Kd cell-surface protein APO-1 is a new member of the nerve growth factor (NGF)/tumor necrosis factor (TNF) receptor superfamily. APO-1 is expressed on…”
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Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes
Published in The Journal of immunology (1950) (01-05-1987)“…Human peripheral blood monocytes were stimulated with lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) alone or in combination. Stimulated but not…”
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Expression of interleukin 2 receptors on activated human B cells
Published in The Journal of experimental medicine (01-11-1984)“…Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for…”
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Endothelial cell vehicles for delivery of cytotoxic genes as a gene therapy approach for carcinoma of the ovary
Published in Clinical cancer research (01-02-1998)“…Human umbilical vein endothelial cells (HUVECs) were evaluated for utility as a vector to achieve a bystander effect and killing of ovarian carcinoma cell…”
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The p75 Peptide is the Receptor for Interleukin 2 Expressed on Large Granular Lymphocytes and is Responsible for the Interleukin 2 Activation of These Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1987)“…There are at least two interleukin 2 (IL-2) binding peptides: one is the Mr 55,000 peptide (p55) reactive with the anti-Tac monoclonal antibody, and the other…”
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Contribution of a p75 Interleukin 2 Binding Peptide to a High-Affinity Interleukin 2 Receptor Complex
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1987)“…There are at least two forms of cellular receptors for interleukin 2 (IL-2); one with a very high affinity and the other with a lower affinity. We identified a…”
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Anti-Tac-H, a Humanized Antibody to the Interleukin 2 Receptor, Prolongs Primate Cardiac Allograft Survival
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1991)“…High-affinity interleukin 2 receptors (IL-2Rs) are expressed by T cells activated in response to foreign histocompatibility antigens but not by normal resting…”
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Association of Intercellular Adhesion Molecule 1 with the Multichain High- Affinity Interleukin 2 Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1990)“…Previously, using flow cytometric resonance energy transfer and lateral diffusion measurements, we demonstrated that a 95-kDa protein identified by two…”
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