Search Results - "GOLDBAUM, Fernando A"

Improvement of Cellulomonas fimi endoglucanase CenA by multienzymatic display on a decameric structural scaffold by Iglesias Rando, Matías R., Gorojovsky, Natalia, Zylberman, Vanesa, Goldbaum, Fernando A., Craig, Patricio O.

“…The development of multifunctional particles using polymeric scaffolds is an emerging technology for many nanobiotechnological applications. Here we present a…”
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Single domain antibodies: promising experimental and therapeutic tools in infection and immunity by Wesolowski, Janusz, Alzogaray, Vanina, Reyelt, Jan, Unger, Mandy, Juarez, Karla, Urrutia, Mariela, Cauerhff, Ana, Danquah, Welbeck, Rissiek, Björn, Scheuplein, Felix, Schwarz, Nicole, Adriouch, Sahil, Boyer, Olivier, Seman, Michel, Licea, Alexei, Serreze, David V., Goldbaum, Fernando A., Haag, Friedrich, Koch-Nolte, Friedrich

“…Antibodies are important tools for experimental research and medical applications. Most antibodies are composed of two heavy and two light chains. Both chains…”
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Blue-Light-Activated Histidine Kinases: Two-Component Sensors in Bacteria by Swartz, Trevor E, Tseng, Tong-Seung, Frederickson, Marcus A, Paris, Gastón, Comerci, Diego J, Rajashekara, Gireesh, Kim, Jung-Gun, Mudgett, Mary Beth, Splitter, Gary A, Ugalde, Rodolfo A, Goldbaum, Fernando A, Briggs, Winslow R, Bogomolni, Roberto A

“…Histidine kinases, used for environmental sensing by bacterial two-component systems, are involved in regulation of bacterial gene expression, chemotaxis,…”
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Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase by Rinaldi, Jimena, Fernández, Ignacio, Shin, Heewhan, Sycz, Gabriela, Gunawardana, Semini, Kumarapperuma, Indika, Paz, Juan M, Otero, Lisandro H, Cerutti, María L, Zorreguieta, Ángeles, Ren, Zhong, Klinke, Sebastián, Yang, Xiaojing, Goldbaum, Fernando A

“…The ability to sense and respond to environmental cues is essential for adaptation and survival in living organisms. In bacteria, this process is accomplished…”
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Light regulates attachment, exopolysaccharide production, and nodulation in Rhizobium leguminosarum through a LOV-histidine kinase photoreceptor by Bonomi, Hernán R, Posadas, Diana M, Paris, Gastón, Carrica, Mariela del Carmen, Frederickson, Marcus, Pietrasanta, Lía Isabel, Bogomolni, Roberto A, Zorreguieta, Angeles, Goldbaum, Fernando A

“…Rhizobium leguminosarum is a soil bacterium that infects root hairs and induces the formation of nitrogen-fixing nodules on leguminous plants. Light, oxygen,…”
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A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers by Llauger, Gabriela, Melero, Roberto, Monti, Demián, Sycz, Gabriela, Huck-Iriart, Cristián, Cerutti, María L, Klinke, Sebastián, Mikkelsen, Evelyn, Tijman, Ariel, Arranz, Rocío, Alfonso, Victoria, Arellano, Sofía M, Goldbaum, Fernando A, Sterckx, Yann G J, Carazo, José-María, Kaufman, Sergio B, Dans, Pablo D, Del Vas, Mariana, Otero, Lisandro H

“…Fijiviruses replicate and package their genomes within viroplasms in a process involving RNA-RNA and RNA-protein interactions. Here, we demonstrate that the 24…”
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LOV Histidine Kinase Modulates the General Stress Response System and Affects the virB Operon Expression in Brucella abortus by Sycz, Gabriela, Carrica, Mariela Carmen, Tseng, Tong-Seung, Bogomolni, Roberto A, Briggs, Winslow R, Goldbaum, Fernando A, Paris, Gastón

“…Brucella is the causative agent of the zoonotic disease brucellosis, and its success as an intracellular pathogen relies on its ability to adapt to the harsh…”
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Brucella spp. Lumazine Synthase Induces a TLR4-Mediated Protective Response against B16 Melanoma in Mice by Rossi, Andrés H, Farias, Ana, Fernández, Javier E, Bonomi, Hernán R, Goldbaum, Fernando A, Berguer, Paula M

“…Brucella Lumazine Synthase (BLS) is a highly immunogenic decameric protein which can accept the fusion of foreign proteins at its ten N-termini. These chimeras…”
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Identification and Characterization of RibN, a Novel Family of Riboflavin Transporters from Rhizobium leguminosarum and Other Proteobacteria by García Angulo, Víctor A, Bonomi, Hernán R, Posadas, Diana M, Serer, María I, Torres, Alfredo G, Zorreguieta, Ángeles, Goldbaum, Fernando A

“…Rhizobia are symbiotic bacteria able to invade and colonize the roots of legume plants, inducing the formation of nodules, where bacteria reduce atmospheric…”
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The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists by Balcazar, Darío E, Vanrell, María Cristina, Romano, Patricia S, Pereira, Claudio A, Goldbaum, Fernando A, Bonomi, Hernán R, Carrillo, Carolina

“…Trypanosomatid parasites represent a major health issue affecting hundreds of million people worldwide, with clinical treatments that are partially effective…”
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A polymeric protein induces specific cytotoxicity in a TLR4 dependent manner in the absence of adjuvants by Berguer, Paula M, Alzogaray, Vanina A, Rossi, Andrés Hugo, Mundiñano, Juliana, Piazzon, Isabel, Goldbaum, Fernando A

“…Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It is possible to insert foreign peptides or proteins at its ten-amino…”
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Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state by Rinaldi, Jimena, Fernández, Ignacio, Poth, Lucía M., Shepard, William E., Savko, Martin, Goldbaum, Fernando A., Klinke, Sebastián

“…The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated…”
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A Polymeric Bacterial Protein Activates Dendritic Cells via TLR4 by Berguer, Paula M, Mundinano, Juliana, Piazzon, Isabel, Goldbaum, Fernando A

“…The enzyme lumazine synthase from Brucella spp. (BLS) is a highly immunogenic protein that folds as a stable dimer of pentamers. It is possible to insert…”
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Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies by Ratier, Laura, Urrutia, Mariela, Paris, Gastón, Zarebski, Laura, Frasch, Alberto C, Goldbaum, Fernando A

“…The sialic acid present in the protective surface mucin coat of Trypanosoma cruzi is added by a membrane anchored trans-sialidase (TcTS), a modified sialidase…”
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Structural Mechanism for Affinity Maturation of an Anti-Lysozyme Antibody by Cauerhff, Ana, Goldbaum, Fernando A., Braden, Bradford C., Eisen, Herman N.

“…In the immune response against a typical T cell-dependent protein antigen, the affinity maturation process is fast and is associated with the early class…”
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Heterologous Prime-Boost Oral Immunization with GK-1 Peptide from Taenia crassiceps Cysticerci Induces Protective Immunity by Fragoso, Gladis, Esquivel-Guadarrama, Fernando, Santana, M. Angélica, Bobes, Raul J., Hernández, Beatriz, Cervantes, Jacquelynne, Segura, René, Goldbaum, Fernando A., Sciutto, Edda, Rosas, Gabriela

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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X-Ray Crystal Structure of an Anti-Buckminsterfullerene Antibody Fab Fragment: Biomolecular Recognition of C60 by Braden, Bradford C., Goldbaum, Fernando A., Chen, Bi-Xing, Kirschner, Austin N., Wilson, Stephen R., Erlanger, Bernard F.

“…We have prepared a monoclonal Buckminsterfullerene specific antibody and report the sequences of its light and heavy chains. We also show, by x-ray…”
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Brucella Lumazine Synthase Elicits a Mixed Th1-Th2 Immune Response and Reduces Infection in Mice Challenged with Brucella abortus 544 Independently of the Adjuvant Formulation Used by VELIKOVSKY, Carlos A, GOLDBAUM, Fernando A, CASSATARO, Juliana, ESTEIN, Silvia, BOWDEN, Raul A, BRUNO, Laura, FOSSATI, Carlos A, GIAMBARTOLOMEI, Guillermo H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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High Order Quaternary Arrangement Confers Increased Structural Stability to Brucella sp. Lumazine Synthase by Zylberman, Vanesa, Craig, Patricio O., Klinke, Sebastián, Braden, Bradford C., Cauerhff, Ana, Goldbaum, Fernando A.

“…The penultimate step in the pathway of riboflavin biosynthesis is catalyzed by the enzyme lumazine synthase (LS). One of the most distinctive characteristics…”
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Affinity Maturation Increases the Stability and Plasticity of the Fv Domain of Anti-protein Antibodies by Acierno, Juan Pablo, Braden, Bradford C., Klinke, Sebastián, Goldbaum, Fernando A., Cauerhff, Ana

“…The somatic mutations accumulated in variable and framework regions of antibodies produce structural changes that increase the affinity towards the antigen…”
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