Search Results - "GOING, James J"

The Pretreatment Systemic Inflammatory Response is an Important Determinant of Poor Pathologic Response for Patients Undergoing Neoadjuvant Therapy for Rectal Cancer by Dreyer, Stephan B., Powell, Arfon G. M. T., McSorley, Stephen T., Waterston, Ashita, Going, James J., Edwards, Joanne, McMillan, Donald C., Horgan, Paul G.

“…Background Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response…”
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Microscopic enteritis: Bucharest consensus by Rostami, Kamran, Aldulaimi, David, Holmes, Geoffrey, Johnson, Matt W, Robert, Marie, Srivastava, Amitabh, Fléjou, Jean-François, Sanders, David S, Volta, Umberto, Derakhshan, Mohammad H, Going, James J, Becheanu, Gabriel, Catassi, Carlo, Danciu, Mihai, Materacki, Luke, Ghafarzadegan, Kamran, Ishaq, Sauid, Rostami-Nejad, Mohammad, Peña, A Salvador, Bassotti, Gabrio, Marsh, Michael N, Villanacci, Vincenzo

“…Microscopic enteritis(ME) is an inflammatory condition of the small bowel that leads to gastrointestinal symptoms,nutrient and micronutrient deficiency.It is…”
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Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer by Witton, Caroline J, Reeves, Jonathan R, Going, James J, Cooke, Timothy G, Bartlett, John MS

“…EGFr/HER1 and c‐erbB‐2/HER2 expression are associated with poor prognosis in breast cancer. The type I receptor tyrosine kinase (RTK) family to which they…”
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Escaping from Flatland: clinical and biological aspects of human mammary duct anatomy in three dimensions by Going, James J, Moffat, David F

“…Accurate knowledge of breast duct anatomy in three dimensions is needed to understand normal breast development, how intraepithelial neoplasia may spread…”
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In healthy volunteers, immunohistochemistry supports squamous to columnar metaplasia as mechanism of expansion of cardia, aggravated by central obesity by Derakhshan, Mohammad H, Robertson, Elaine V, Yeh Lee, Yeong, Harvey, Tim, Ferrier, Rod K, Wirz, Angela A, Orange, Clare, Ballantyne, Stuart A, Hanvey, Scott L, Going, James J, McColl, Kenneth E L

“…Recently, we showed that the length of cardiac mucosa in healthy volunteers correlated with age and obesity. We have now examined the immunohistological…”
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Raf Kinase Inhibitor Protein Expression in a Survival Analysis of Colorectal Cancer Patients by Al-Mulla, Fahd, Hagan, Suzanne, Behbehani, Abdulla I, Bitar, Milad S, George, Shirley S, Going, James J, García, Jorge J Curto, Scott, Lucy, Fyfe, Nicky, Murray, Graeme I, Kolch, Walter

“…Raf kinase inhibitor protein (RKIP) inhibits the Raf and nuclear factor kappa B signaling pathways, and suppresses metastasis in animal models. We examined…”
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Systematic Four-Quadrant Biopsy Detects Barrett's Dysplasia in More Patients Than Nonsystematic Biopsy by ABELA, Jo-Etienne, GOING, James J, MACKENZIE, John F, MCKERNAN, Margaret, O'MAHONEY, Sylvia, STUART, Robert C

“…To compare detection of Barrett's dysplasia and adenocarcinoma by systematic versus nonsystematic surveillance biopsy protocols. Upper GI consultation and…”
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An unexpected mucosal metaplasia at the gastric cardia in longstanding pernicious anemia by Derakhshan, Mohammad H, Crumley, Andrew, Forshaw, Matthew, Mitchell, David R, Going, James J

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Serum ghrelin; a new surrogate marker of gastric mucosal alterations in upper gastrointestinal carcinogenesis by Sadjadi, Alireza, Yazdanbod, Abbas, Lee, Yeong Yeh, Boreiri, Majid, Samadi, Fatemeh, Alizadeh, Behrooz Z, Islami, Farhad, Fyfe, Valerie, Babaei, Masoud, Namazi, Mohammad J, Going, James J, Sotoudeh, Masoud, de Bock, Geertruida H, Malekzadeh, Reza, Derakhshan, Mohammad H

“…A few studies have indicated inverse relationships between serum ghrelin and gastric and esophageal cancers but those associations have been restricted to…”
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Interrelationships between Tumor Proliferative Activity, Leucocyte and Macrophage Infiltration, Systemic Inflammatory Response, and Survival in Patients Selected for Potentially Curative Resection for Gastroesophageal Cancer by Crumley, Andrew B. C., Going, James J., Hilmy, Mustafa, Dutta, Sumanta, Tannahill, Claire, McKernan, Margaret, Edwards, Joanne, Stuart, Robert C., McMillan, Donald C.

“…Background A number of accepted criteria, including pathological tumor, node, metastasis system stage, lymph node metastasis, and tumor differentiation,…”
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Comparison of visual and automated assessment of microvessel density and their impact on outcome in primary operable invasive ductal breast cancer by Mohammed, Zahra M.A., MSc, Orange, Clare, BSc, McMillan, Donald C., PhD, Mallon, Elizabeth, PhD, Doughty, Julie C., PhD, Edwards, Joanne, PhD, Going, James J., PhD

“…Summary Angiogenesis is essential for tumor growth and metastasis, and several studies have reported increased angiogenesis, as quantified by microvessel…”
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Human breast duct anatomy, the 'sick lobe' hypothesis and intraductal approaches to breast cancer by GOING, James J, MOHUN, Timothy J

“…Information about central and peripheral duct anatomy is a requirement for developing intraductal approaches to human breast cancer, but remains sparse. This…”
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The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer by van Wyk, Hester C, Park, James H, Edwards, Joanne, Horgan, Paul G, McMillan, Donald C, Going, James J

“…Background: Tumour budding has been reported to reflect invasiveness, metastasis and unfavourable prognosis in colorectal cancer. The aim of the study was to…”
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Positive Mobilization Margins Alone Do Not Influence Survival Following Pancreatico-Duodenectomy for Pancreatic Ductal Adenocarcinoma by JAMIESON, Nigel B, FOULIS, Alan K, OIEN, Karin A, GOING, James J, GLEN, Paul, DICKSON, Euan J, IMRIE, Clem W, MCKAY, Colin J, CARTER, Ross

“…To determine the prognostic influence of residual tumor at or within 1 mm of the mobilization margins (R1Mobilization) compared with transection margins…”
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ROC-king onwards: intraepithelial lymphocyte counts, distribution & role in coeliac disease mucosal interpretation by Rostami, Kamran, Marsh, Michael N, Johnson, Matt W, Mohaghegh, Hamid, Heal, Calvin, Holmes, Geoffrey, Ensari, Arzu, Aldulaimi, David, Bancel, Brigitte, Bassotti, Gabrio, Bateman, Adrian, Becheanu, Gabriel, Bozzola, Anna, Carroccio, Antonio, Catassi, Carlo, Ciacci, Carolina, Ciobanu, Alexandra, Danciu, Mihai, Derakhshan, Mohammad H, Elli, Luca, Ferrero, Stefano, Fiorentino, Michelangelo, Fiorino, Marilena, Ganji, Azita, Ghaffarzadehgan, Kamran, Going, James J, Ishaq, Sauid, Mandolesi, Alessandra, Mathews, Sherly, Maxim, Roxana, Mulder, Chris J, Neefjes-Borst, Andra, Robert, Marie, Russo, Ilaria, Rostami-Nejad, Mohammad, Sidoni, Angelo, Sotoudeh, Masoud, Villanacci, Vincenzo, Volta, Umberto, Zali, Mohammad R, Srivastava, Amitabh

“…Counting intraepithelial lymphocytes (IEL) is central to the histological diagnosis of coeliac disease (CD), but no definitive 'normal' IEL range has ever been…”
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Central Obesity in Asymptomatic Volunteers Is Associated With Increased Intrasphincteric Acid Reflux and Lengthening of the Cardiac Mucosa by Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Lee, Yeong Yeh, Seenan, John Paul, Ballantyne, Stuart A, Hanvey, Scott L, Kelman, Andrew W, Going, James J, McColl, Kenneth E.L

“…Background & Aims In the West, a substantial proportion of subjects with adenocarcinoma of the gastric cardia and gastroesophageal junction have no history…”
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Worldwide Inverse Association between Gastric Cancer and Esophageal Adenocarcinoma Suggesting a Common Environmental Factor Exerting Opposing Effects by Derakhshan, Mohammad H, Arnold, Melina, Brewster, David H, Going, James J, Mitchell, David R, Forman, David, McColl, Kenneth E L

“…The incidence of esophageal adenocarcinoma (EAC) is increasing while adenocarcinoma of the stomach is decreasing. We have investigated whether the incidences…”
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A single nucleotide polymorphism in codon F31I and V57I of the AURKA gene in invasive ductal breast carcinoma in Middle East by Golmohammadi, Rahim, Namazi, Mohammad Javed, Going, James J., Derakhshan, Mohammad H.

“…Although few studies have suggested a carcinogenic role for polymorphism of F31I and V57I codons of AURKA gene in invasive ductal carcinoma, contradictory…”
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Immunohistochemical detection improves the prognostic value of lymphatic and blood vessel invasion in primary ductal breast cancer by Gujam, Fadia J A, Going, James J, Mohammed, Zahra M A, Orange, Clare, Edwards, Joanne, McMillan, Donald C

“…Lymphovascular invasion (LBVI) including lymphatic (LVI) and blood (BVI) vessel invasion is a critical step in cancer metastasis. In breast cancer, the optimal…”
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Epithelial carcinogenesis: challenging monoclonality by Going, James J

“…How carcinomas begin remains unclear, but experimental data do not entirely exclude the participation of more than one clone of neoplastic cells, even in…”
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