Search Results - "GOI, K"

Microstructure formation of porous sintered Ti–Si–Zr compacts with mechanically alloyed-activated Ti–Si and TiH2 powders by Jarfors, A.E.W., Butler, D.L., Goi, K.L.S.

“…•From the study it is clear that mechanical alloying effectively aids the formation of Ti3Si.•The presence of TiH2 aids the sintering process through the…”
Get full text

Hypercalcemia in childhood acute lymphoblastic leukemia : frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19 by INUKAI, T, HIROSE, K, GOTO, H, ENDO, M, MORIMOTO, A, IMAIZUMI, M, KAWAMURA, N, MIYAJIMA, Y, OHTAKE, M, MIYAJI, R, SAITO, M, TAWA, A, INABA, T, YANAI, F, GOI, K, NAKAZAWA, S, SUGITA, K, KUROSAWA, H, HAMA, A, INADA, H, CHIN, M, NAGATOSHI, Y, OHTSUKA, Y, ODA, M

“…Hypercalcemia is relatively rare but clinically important complication in childhood leukemic patients. To clarify the clinical characteristics, mechanisms of…”
Get full text

TGFβ1 synergizes with FLT3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with MLL gene rearrangements by Tamai, M., Furuichi, Y., Kasai, S., Ando, N., Harama, D., Goi, K., Inukai, T., Kagami, K., Abe, M., Ichikawa, H., Sugita, K.

“…•TGFβ1 mRNA is enhanced by FL stimulation in MLL + ALL cells.•TGFβ1 and FL synergistically induce MLL + ALL cells into cell-cycle arrest because of marked…”
Get full text

BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia by Kuroda, I, Inukai, T, Zhang, X, Kikuchi, J, Furukawa, Y, Nemoto, A, Akahane, K, Hirose, K, Honna-Oshiro, H, Goi, K, Kagami, K, Yagita, H, Tauchi, T, Maeda, Y, Sugita, K

“…Allogeneic stem cell transplantation (allo-SCT) is a potentially curative therapy for chronic myeloid leukemia and Philadelphia chromosome-positive (Ph(+))…”
Get full text

Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors by Zhang, X, Inukai, T, Hirose, K, Akahane, K, Kuroda, I, Honna-Oshiro, H, Kagami, K, Goi, K, Nakamura, K, Kobayashi, M, Endo, M, Yagita, H, Kurosawa, H, Thomas Look, A, Honda, H, Inaba, T, Nakazawa, S, Sugita, K

“…t (17;19)-acute lymphoblastic leukemia (ALL) shows extremely poor prognosis. E2A-HLF derived from t (17;19) blocks apoptosis induced by the intrinsic…”
Get full text

Fertility recovery and pregnancy after allogeneic hematopoietic stem cell transplantation in Fanconi anemia patients by NABHAN, Samir K, BITENCOURT, Marco A, SANDERS, Jean, SNOWDEN, John, YALE, Hiromasa, PASQUINI, Ricardo, GLUCKMAN, Eliane, DUVAL, Michel, ABECASIS, Manuel, DUFOUR, Carlo, BOUDJEDIR, Karim, ROCHA, Vanderson, SOCIE, Gérard, PASSWEG, Jakob, GOI, Kumiko

“…Reduced fertility is one clinical manifestation among other well known Fanconi anemia features. Most recipients of allogeneic hematopoietic stem cell…”
Get full text

Elastic modulus of sintered porous Ti-Si-Zr, using activation by Ti-Si mechanically alloyed powder and TiH2 powder by GOI, K. L. S, BUTLER, D. L, JARFORS, A. E. W, YONG, J. M. S, LIMB, D. C. S

“…A novel biomaterial based on Ti-Si-Zr was developed using the sintering process with a composition targeting at a bulk modulus in the same range as that of…”
Get full text

Successful tandem (autologous-cord blood) SCT in advanced neuroblastomas with highly amplified MYCN by Goi, K, Inukai, T, Honna, H, Akahane, K, Hirose, K, Kuroda, I, Hasuda, N, Koshizuka, K, Takano, K, Sugita, K

“…Although autologous tandem hematopoietic SCT has improved the prognosis of patients with advanced high-risk neuroblastoma, the results remain unsatisfactory…”
Get full text

Specific induction of CD33 expression by E2A-HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor by Akahane, K, Inukai, T, Inaba, T, Kurosawa, H, Look, A T, Kiyokawa, N, Fujimoto, J, Goto, H, Endo, M, Zhang, X, Hirose, K, Kuroda, I, Honna, H, Kagami, K, Goi, K, Nakazawa, S, Sugita, K

Get full text

Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity by INUKAI, T, ZHANG, X, HONNA, H, KAGAMI, K, NAKAMOTO, K, YAGITA, H, OKUMURA, K, KOYAMA-OKAZAKI, T, NAKAZAWA, S, SUGITA, K, GOTO, M, HIROSE, K, UNO, K, AKAHANE, K, NEMOTO, A, GOI, K, SATO, H, TAKAHASHI, K

“…Malignant cells generally acquire some immune escape mechanisms for clonal expansion. Immune escape mechanisms also contribute to the failure of…”
Get full text

Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity by Yamakawa-Karakida, N, Sugita, K, Inukai, T, Goi, K, Nakamura, M, Uno, K, Sato, H, Kagami, K, Barker, N, Nakazawa, S

“…The peroxisome proliferator-activated receptor gamma (PPAR gamma), a member of the nuclear receptor superfamily, is expressed at highest levels in adipose…”
Get full text

The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome by MIYAMOTO, N, SUGITA, K, GOI, K, INUKAI, T, LIJIMA, K, TEZUKA, T, KOJIKA, S, NAKAMURA, M, KAGAMI, K, NAKAZAWA, S

“…The Janus kinase (JAK) family is one of intracellular protein tyrosine kinases (PTKs) present in hematopoietic and lymphoid cells and has been shown to play a…”
Get full text

Little impact of donor recipient major mismatch for neutrophil-specific antigen NA2 on neutrophil recovery after allogeneic SCT by Inukai, T, Goi, K, Tezuka, T, Uno, K, Nemoto, A, Takahashi, K, Sato, H, Akahane, K, Hirose, K, Honna, H, Kuroda, I, Kagami, K, Nakamoto, K, Taniguchi, K, Nakazawa, S, Sugita, K

“…The Fcγ receptor IIIb (FcγRIIIb), a receptor for the Fcγ region of IgG, is specifically expressed on neutrophils. It has two allelic polymorphisms, NA1 and…”
Get full text

A successful case of allogeneic bone marrow transplantation for osteosarcoma with multiple metastases of lung and bone by Goi, K, Sugita, K, Tezuka, T, Sato, H, Uno, K, Inukai, T, Hamada, Y, Nakazawa, S

Get full text

Clonotypic analysis of acute lymphoblastic leukemia with a double TEL-AML1 fusion at onset and relapse by Inukai, T, Yokota, S, Okamoto, T, Nemoto, A, Akahane, K, Takahashi, K, Sato, H, Goi, K, Nakazawa, S, Sugita, K

Get full text

The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1 by Dang, J, Inukai, T, Kurosawa, H, Goi, K, Inaba, T, Lenny, N T, Downing, J R, Stifani, S, Look, A T

“…The E2A-HLF fusion gene, formed by the t(17;19)(q22;p13) chromosomal translocation in leukemic pro-B cells, encodes a chimeric transcription factor consisting…”
Get full text

Revision of the cytological diagnosis of CNS relapse into aseptic meningitis in a patient with TEL-AML1+ acute lymphoblastic leukaemia by FISH analysis of mononuclear cells in cerebrospinal fluid by Inukai, T, Akahane, K, Nemoto, A, Kuroda, I, Noguchi, S, Hirose, K, Honna, H, Goi, K, Kondo, T, Iwasa, S, Murata, S, Kato, R, Nakazawa, S, Sugita, K

Get full text

Non-T-cell-depleted HLA haploidentical stem cell transplantation based on feto-maternal microchimerism in pediatric patients with advanced malignancies by Yoshihara, T, Morimoto, A, Inukai, T, Kuroda, H, Ishida, H, Sugita, K, Goi, K, Imamura, T, Todo, S, Maruya, E, Saji, H, Nakazawa, S, Imashuku, S

Get full text

p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in childhood acute lymphoblastic leukemia with 11q23 translocation by NAKAMURA, M, SUGITA, K, KAGAMI, K, O-KOYAMA, T, MORI, T, NAKAZAWA, S, INUKAI, T, GOI, K, IIJIMA, K, TEZUKA, T, KOJIKA, S, SHIRAISHI, K, MIYAMOTO, N, KARAKIDA, N

“…The p16 gene encoding a specific inhibitor of cyclin-dependent kinases 4 and 6 has been reported to be inactivated at a variety of rates in malignant tumors…”
Get full text

Participation of granulocyte colony-stimulating factor in the growth regulation of leukemia cells from Philadelphia chromosome-positive acute leukemia and blast crisis of chronic myeloid leukemia by INUKAI, T, SUGITA, K, SUZUKI, T, OKAZAKI-KOYAMA, T, NAKAZAWA, S, MITSUI, K, LIJIMA, K, GOI, K, TEZUKA, T, KOJIKA, S, KAGAMI, K, MORI, T, KINOSHITA, A

“…Granulocyte colony-stimulating factor (G-CSF) has been shown to support the growth of multipotential hematopoietic stem cells in addition to the cells of…”
Get full text