Search Results - "GODEJOHANN, Markus"

Hydrophilic interaction chromatography coupled to nuclear magnetic resonance spectroscopy and mass spectroscopy—A new approach for the separation and identification of extremely polar analytes in bodyfluids by Godejohann, Markus

“…A method for the unambiguous identification of highly polar molecules based on the separation on a silica gel column run in hydrophilic interaction…”
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Chemical Composition of Fat Bloom on Chocolate Products Determined by Combining NMR and HPLC-MS by Trapp, Lena, Karschin, Niels, Godejohann, Markus, Schacht, Hilke, Nirschl, Hermann, Guthausen, Gisela

“…To reduce unwanted fat bloom in the manufacturing and storage of chocolates, detailed knowledge of the chemical composition and molecular mobility of the oils…”
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Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses by Kampa, Annette, Gagunashvili, Andrey N, Gulder, Tobias A M, Morinaka, Brandon I, Daolio, Cristina, Godejohann, Markus, Miao, Vivian P W, Piel, Jörn, Andrésson, Ólafur S

“…Bacteria are a major source of natural products that provide rich opportunities for both chemical and biological investigation. Although the vast majority of…”
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Phenylketonuria (PKU) Urinary Metabolomic Phenotype Is Defined by Genotype and Metabolite Imbalance: Results in 51 Early Treated Patients Using Ex Vivo 1H-NMR Analysis by Cannet, Claire, Bayat, Allan, Frauendienst-Egger, Georg, Freisinger, Peter, Spraul, Manfred, Himmelreich, Nastassja, Kockaya, Musa, Ahring, Kirsten, Godejohann, Markus, MacDonald, Anita, Trefz, Friedrich

“…Phenylketonuria (PKU) is a rare metabolic disorder caused by mutations in the phenylalanine hydroxylase gene. Depending on the severity of the genetic…”
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Screening for Triterpenoid Saponins in Plants Using Hyphenated Analytical Platforms by Khakimov, Bekzod, Tseng, Li Hong, Godejohann, Markus, Bak, Søren, Engelsen, Søren Balling

“…Recently the number of studies investigating triterpenoid saponins has drastically increased due to their diverse and potentially attractive biological…”
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Identification of the metabolites of ivermectin in humans by Tipthara, Phornpimon, Kobylinski, Kevin C., Godejohann, Markus, Hanboonkunupakarn, Borimas, Roth, Alison, Adams, John H., White, Nicholas J., Jittamala, Podjanee, Day, Nicholas P. J., Tarning, Joel

“…Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its…”
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High-Resolution Quantitative Metabolome Analysis of Urine by Automated Flow Injection NMR by Da Silva, Laeticia, Godejohann, Markus, Martin, François-Pierre J, Collino, Sebastiano, Bürkle, Alexander, Moreno-Villanueva, María, Bernhardt, Jürgen, Toussaint, Olivier, Grubeck-Loebenstein, Beatrix, Gonos, Efstathios S, Sikora, Ewa, Grune, Tilman, Breusing, Nicolle, Franceschi, Claudio, Hervonen, Antti, Spraul, Manfred, Moco, Sofia

“…Metabolism is essential to understand human health. To characterize human metabolism, a high-resolution read-out of the metabolic status under various…”
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Metabolic Profiling Framework for Discovery of Candidate Diagnostic Markers of Malaria by Tritten, Lucienne, Keiser, Jennifer, Godejohann, Markus, Utzinger, Jürg, Vargas, Mireille, Beckonert, Olaf, Holmes, Elaine, Saric, Jasmina

“…Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of…”
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Characterization of a paracetamol metabolite using on-line LC-SPE-NMR-MS and a cryogenic NMR probe by Godejohann, Markus, Tseng, Li-Hong, Braumann, Ulrich, Fuchser, Jens, Spraul, Manfred

“…In this study, the hyphenation of LC-SPE-NMR-MS at 500 MHz was applied to the structural elucidation of a low concentrated paracetamol metabolite present in…”
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LC-DAD-MS/SPE-NMR Hyphenation. A Tool for the Analysis of Pharmaceutically Used Plant Extracts:  Identification of Isobaric Iridoid Glycoside Regioisomers from Harpagophytum procumbens by SEGER, Christoph, GODEJOHANN, Markus, TSENG, Li-Hong, SPRAUL, Manfred, GIRTLER, Anny, STURM, Sonja, STUPPNER, Hermann

“…LC-DAD-MS monitored fractionation of a Harpagophytum procumbens DC. (Pedaliaceae) root extract was combined with a hyphenated LC-DAD-MS/SPE-NMR technique, thus…”
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Fungal Biotransformation Products of Dehydroabietic Acid by van Beek, Teris A, Claassen, Frank W, Dorado, Jose, Godejohann, Markus, Sierra-Alvarez, Reyes, Wijnberg, Joannes B. P. A

“…Dehydroabietic acid (DHA) (1) is one of the main compounds in Scots pine wood responsible for aquatic and microbial toxicity. The degradation of 1 by Trametes…”
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Identification of tentative marker in Corvina and Primitivo wines with CMC‐se by Kessler, Pavel, Godejohann, Markus

“…This paper introduces CMC‐se—a program for computer‐assisted structure elucidation. In the experimental part, the combination of modern analytical methods…”
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Characterization of Asphaltenes Precipitated at Different Solvent Power Conditions Using Atmospheric Pressure Photoionization (APPI) and Laser Desorption Ionization (LDI) Coupled to Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS) by Witt, Matthias, Godejohann, Markus, Oltmanns, Sven, Moir, Michael, Rogel, Estrella

“…In the present work, asphaltenes obtained using different n-heptane/crude oil ratios (HCORs) were analyzed using atmospheric pressure photoionization (APPI)…”
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Separation and identification of a complex flurbiprofen-polyethylene glycol mono- and diester mixture via a hyphenated HPLC-DAD-HRMS/SPE NMR system by Schmidt, Philipp, Kolb, Christine, Godejohann, Markus, Reiser, Andreas, Philipp, Markus, Müller, Hans-Christian, Karaghiosoff, Konstantin

“…We report the use of a hyphenated HPLC-DAD(diode array detector)-HRMS/SPE NMR system for the separation and isolation of a complex mixture of esters,…”
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Phenylketonuria Urinary Metabolomic Phenotype Is Defined by Genotype and Metabolite Imbalance: Results in 51 Early Treated Patients Using Ex Vivo [sup.1]H-NMR Analysis by Cannet, Claire, Bayat, Allan, Frauendienst-Egger, Georg, Freisinger, Peter, Spraul, Manfred, Himmelreich, Nastassja, Kockaya, Musa, Ahring, Kirsten, Godejohann, Markus, MacDonald, Anita, Trefz, Friedrich

“…Phenylketonuria (PKU) is a rare metabolic disorder caused by mutations in the phenylalanine hydroxylase gene. Depending on the severity of the genetic…”
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Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography–time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry by Godejohann, Markus, Berset, Jean-Daniel, Muff, Daniel

“…► We describe an approach for the completely non-targeted analysis of complex mixtures based on the universal response of proton detected nuclear magnetic…”
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Metabolomics of B to Plasma Cell Differentiation by Garcia-Manteiga, Jose Manuel, Mari, Silvia, Godejohann, Markus, Spraul, Manfred, Napoli, Claudia, Cenci, Simone, Musco, Giovanna, Sitia, Roberto

“…When small B lymphocytes bind antigen in the context of suitable signals, a profound geno-proteomic metamorphosis is activated that generates…”
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Formation of a Thiol–Ene Addition Product of Asthma Medication Montelukast Caused by a Widespread Tin-Based Thermal Stabilizer by Schmidt, Philipp, Kolb, Christine, Reiser, Andreas, Philipp, Markus, Godejohann, Markus, Helmboldt, Hannes, Müller, Hans-Christian, Karaghiosoff, Konstantin

“…We report the formation and characterization of two diastereomeric thiol–ene addition products of the asthma medication Montelukast within chewing tablets…”
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Identification of potential interferents of methylmalonic acid: A previously unrecognized pitfall in clinical diagnostics and newborn screening by Monostori, Péter, Godejohann, Markus, Janda, Joachim, Galla, Zsolt, Rácz, Gábor, Klinke, Glynis, Szatmári, Ildikó, Zsidegh, Petra, Kohlmüller, Dirk, Kölker, Stefan, Hoffmann, Georg F., Gramer, Gwendolyn, Okun, Jürgen G.

“…•Interferents of methylmalonic acid can lead to invalid diagnoses in clinical assays.•Samples from patients with propionic and methylmalonic acidurias were…”
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NMR spectroscopy of wastewater: A review, case study, and future potential by Anaraki, Maryam Tabatabaei, Lysak, Daniel H., Downey, Katelyn, Kock, Flávio Vinicius Crizóstomo, You, Xiang, Majumdar, Rudraksha D., Barison, Andersson, Lião, Luciano Morais, Ferreira, Antonio Gilberto, Decker, Venita, Goerling, Benjamin, Spraul, Manfred, Godejohann, Markus, Helm, Paul A., Kleywegt, Sonya, Jobst, Karl, Soong, Ronald, Simpson, Myrna J., Simpson, Andre J.

“…[Display omitted] •Wastewater composition has implications for environmental and human health.•NMR is incredibly powerful for studying molecular structure and…”
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