Search Results - "GLASSCOCK, Jarret"

T cell subtype profiling measures exhaustion and predicts anti-PD-1 response by Schillebeeckx, Ian, Earls, Jon, Flanagan, Kevin C., Hiken, Jeffrey, Bode, Alex, Armstrong, Jon R., Messina, David N., Adkins, Douglas, Ley, Jessica, Alborelli, Ilaria, Jermann, Philip, Glasscock, Jarret I.

“…Anti-PD-1 therapy can provide long, durable benefit to a fraction of patients. The on-label PD-L1 test, however, does not accurately predict response. To build…”
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Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade by Boothby, Thomas C., Tenlen, Jennifer R., Smith, Frank W., Wang, Jeremy R., Patanella, Kiera A., Nishimura, Erin Osborne, Tintori, Sophia C., Li, Qing, Jones, Corbin D., Yandell, Mark, Messina, David N., Glasscock, Jarret, Goldstein, Bob

“…Horizontal gene transfer (HGT), or the transfer of genes between species, has been recognized recently as more pervasive than previously suspected. Here, we…”
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Whole-genome sequencing and variant discovery in C. elegans by Mardis, Elaine R, Hillier, LaDeana W, Marth, Gabor T, Quinlan, Aaron R, Dooling, David, Fewell, Ginger, Barnett, Derek, Fox, Paul, Glasscock, Jarret I, Hickenbotham, Matthew, Huang, Weichun, Magrini, Vincent J, Richt, Ryan J, Sander, Sacha N, Stewart, Donald A, Stromberg, Michael, Tsung, Eric F, Wylie, Todd, Schedl, Tim, Wilson, Richard K

“…Massively parallel sequencing instruments enable rapid and inexpensive DNA sequence data production. Because these instruments are new, their data require…”
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A large microRNA cluster on chromosome 19 is a transcriptional hallmark of WHO type A and AB thymomas by Radovich, Milan, Solzak, Jeffrey P, Hancock, Bradley A, Conces, Madison L, Atale, Rutuja, Porter, Ryan F, Zhu, Jin, Glasscock, Jarret, Kesler, Kenneth A, Badve, Sunil S, Schneider, Bryan P, Loehrer, Patrick J

“…Background: Thymomas are one of the most rarely diagnosed malignancies. To better understand its biology and to identify therapeutic targets, we performed…”
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Bovine exome sequence analysis and targeted SNP genotyping of recessive fertility defects BH1, HH2, and HH3 reveal a putative causative mutation in SMC2 for HH3 by McClure, Matthew C, Bickhart, Derek, Null, Dan, Vanraden, Paul, Xu, Lingyang, Wiggans, George, Liu, George, Schroeder, Steve, Glasscock, Jarret, Armstrong, Jon, Cole, John B, Van Tassell, Curtis P, Sonstegard, Tad S

“…The recent discovery of bovine haplotypes with negative effects on fertility in the Brown Swiss, Holstein, and Jersey breeds has allowed producers to identify…”
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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma by Flanagan, Kevin C., Earls, Jon, Schillebeeckx, Ian, Hiken, Jeffrey, Wellinghoff, Rachel L., LaFranzo, Natalie A., Bradley, Zachary S., Babbitt, Joey, Westra, William H., Hsu, Raymond, Nadauld, Lincoln, Mcleod, Howard, Firth, Sean D., Sharp, Brittany, Fuller, Josh, Vavinskaya, Vera, Sutton, Leisa, Deichaite, Ida, Bailey, Samuel D., Sandulache, Vlad C., Rendo, Matthew J., Macdonald, Orlan K., Welaya, Karim, Wade, James L., Pippas, Andrew W., Slim, Jennifer, Bank, Bruce, Saccaro, Steven J., Sui, Xingwei, Akhtar, Adil, Balaraman, Savitha, Kossman, Steven E., Sonnier, Scott A., Shenkenberg, Todd D., Alexander, Warren L., Price, Katherine A., Bane, Charles L., Ley, Jessica, Messina, David N., Glasscock, Jarret I., Cohen, Ezra E. W., Adkins, Douglas R., Duncavage, Eric J.

“…Purpose Anti-PD-1 therapy provides clinical benefit in 40–50% of patients with relapsed and/or metastatic head and neck squamous cell carcinoma (RM-HNSCC)…”
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Analytical Performance of an Immunoprofiling Assay Based on RNA Models by Schillebeeckx, Ian, Armstrong, Jon R., Forys, Jason T., Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C., Cui, Tiange, Glasscock, Jarret I., Messina, David N., Duncavage, Eric J.

“…As immuno-oncology drugs grow more popular in the treatment of cancer, better methods are needed to quantify the tumor immune cell component to determine which…”
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Evolutionary toggling of the MAPT 17q21.31 inversion region by Warren, Wesley C, Cardone, Maria Francesca, Abouelleil, Amr, Hardy, John, Hillier, LaDeana W, Glasscock, Jarret, Eichler, Evan E, Jiang, Zhaoshi, Graves, Tina A, Chen, Lin, Reily, Amy Denise, Antonacci, Francesca, Kidd, Jeffrey M, Fung, Hon-Chung, Wallis, John, Zody, Michael C, Duckworth, Jaime, Wilson, Richard K, Cheng, Ze, Ventura, Mario

“…Evan Eichler and colleagues present a sequence assembly of the inverted H2 haplotype of human chromosome 17q21.31 and show that the inversion is polymorphic in…”
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Molecular Properties of Adult Mouse Gastric and Intestinal Epithelial Progenitors in Their Niches by Giannakis, Marios, Stappenbeck, Thaddeus S., Mills, Jason C., Leip, Douglas G., Lovett, Michael, Clifton, Sandra W., Ippolito, Joseph E., Glasscock, Jarret I., Arumugam, Manimozhiyan, Brent, Michael R., Gordon, Jeffrey I.

“…We have sequenced 36,641 expressed sequence tags from laser capture microdissected adult mouse gastric and small intestinal epithelial progenitors, obtaining…”
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The value of avian genomics to the conservation of wildlife by Romanov, Michael N, Tuttle, Elaina M, Houck, Marlys L, Modi, William S, Chemnick, Leona G, Korody, Marisa L, Mork, Emily M Stremel, Otten, Christie A, Renner, Tanya, Jones, Kenneth C, Dandekar, Sugandha, Papp, Jeanette C, Da, Yang, Green, Eric D, Magrini, Vincent, Hickenbotham, Matthew T, Glasscock, Jarret, McGrath, Sean, Mardis, Elaine R, Ryder, Oliver A

“…Genomic studies in non-domestic avian models, such as the California condor and white-throated sparrow, can lead to more comprehensive conservation plans and…”
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Using RNA Sequencing and In Silico Subtraction to Identify Resistance Gene Analog Markers for Lr16 in Wheat by Harrison, Nicole Rezac, Fritz, Allan K., Glasscock, Jarret I., Ahmed, Sara, Messina, David N., Amand, Paul St, Fellers, John P.

“…Leaf rust, caused by Puccinia triticina Eriks., is one of the most widespread diseases of wheat and breeding for resistance is one of the most effective…”
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Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study by Flanagan, Kevin C, Earls, Jon, Hiken, Jeffrey, Wellinghoff, Rachel L, Ponder, Michelle M, McLeod, Howard L, Westra, William H, Vavinskaya, Vera, Sutton, Leisa, Deichaite, Ida, Macdonald, Orlan K, Welaya, Karim, Wade, James, Azzi, Georges, Pippas, Andrew W, Slim, Jennifer, Bank, Bruce, Sui, Xingwei, Kossman, Steven E, Shenkenberg, Todd D, Alexander, Warren L, Price, Katharine A, Ley, Jessica, Messina, David N, Glasscock, Jarret I, Colevas, A Dimitrios, Cohen, Ezra E W, Adkins, Douglas, Duncavage, Eric J

“…Background Despite advances in cancer care and detection, >65% of patients with squamous cell cancer of the head and neck (HNSCC) will develop recurrent and/or…”
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DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome by Locke, Devin, Conyers, Joshua, Hickenbotham, Matthew, Dooling, David, McGrath, Sean, Abbott, Rachel, Shannon, William D, Gordon, David, Zhao, Yu, Baty, Jack, Mardis, Elaine R, Glasscock, Jarret, Ding, Li, Link, Daniel C, Shi, Xiaoqi, Heath, Sharon, Tomasson, Michael H, Walter, Matthew J, Hillier, LaDeana W, Chinwalla, Asif, Wylie, Todd, Sander, Nathan, Ley, Timothy J, Abbott, Scott, Westervelt, Peter, Pohl, Craig, Hawkins, Amy, Graubert, Timothy A, Smith, Scott, Larson, David E, Wilson, Richard K, Cook, Lisa, Ries, Rhonda E, Payton, Jacqueline E, McLellan, Michael D, Chen, Ken, DiPersio, John F, Dunford-Shore, Brian H, Magrini, Vincent, Nagarajan, Rakesh, Koboldt, Dan C, Fulton, Lucinda, Watson, Mark, Ivanovich, Jennifer, Fulton, Bob, Miner, Tracie, Minx, Patrick, Osborne, John R

“…Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about 13,000 adults in the United States each year. The treatment of this…”
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An ORFeome-based analysis of human transcription factor genes and the construction of a microarray to interrogate their expression by Messina, David N, Glasscock, Jarret, Gish, Warren, Lovett, Michael

“…Transcription factors (TFs) are essential regulators of gene expression, and mutated TF genes have been shown to cause numerous human genetic diseases. Yet to…”
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Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank by Pardo, Ivanesa, Lillemoe, Heather A, Blosser, Rachel J, Choi, MiRan, Sauder, Candice A M, Doxey, Diane K, Mathieson, Theresa, Hancock, Bradley A, Baptiste, Dadrie, Atale, Rutuja, Hickenbotham, Matthew, Zhu, Jin, Glasscock, Jarret, Storniolo, Anna Maria V, Zheng, Faye, Doerge, R W, Liu, Yunlong, Badve, Sunil, Radovich, Milan, Clare, Susan E

“…Our efforts to prevent and treat breast cancer are significantly impeded by a lack of knowledge of the biology and developmental genetics of the normal mammary…”
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Flipping NextGen: using biological systems to characterize NextGen sequencing technologies by Glasscock, Jarret, Richt, Ryan, Hickenbotham, Matt

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Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing by Radovich, Milan, Clare, Susan E., Atale, Rutuja, Pardo, Ivanesa, Hancock, Bradley A., Solzak, Jeffrey P., Kassem, Nawal, Mathieson, Theresa, Storniolo, Anna Maria V., Rufenbarger, Connie, Lillemoe, Heather A., Blosser, Rachel J., Choi, Mi Ran, Sauder, Candice A., Doxey, Diane, Henry, Jill E., Hilligoss, Eric E., Sakarya, Onur, Hyland, Fiona C., Hickenbotham, Matthew, Zhu, Jin, Glasscock, Jarret, Badve, Sunil, Ivan, Mircea, Liu, Yunlong, Sledge, George W., Schneider, Bryan P.

“…Triple-negative breast cancers (TNBCs) are a heterogeneous set of tumors defined by an absence of actionable therapeutic targets (ER, PR, and HER-2)…”
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Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 for HH3 by McClure, Matthew C, Bickhart, Derek, Null, Dan, VanRaden, Paul, Xu, Lingyang, Wiggans, George, Schroeder, Steve, Glasscock, Jarret, Armstrong, Jon, Cole, John B, Van Tassell, Curtis P, Sonstegard, Tad S

“…The recent discovery of bovine haplotypes with negative effects on fertility in the Brown Swiss, Holstein, and Jersey breeds has allowed producers to identify…”
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Abstract 4858: Next-generation whole transcriptome sequencing of thymic malignancies by Radovich, Milan, Hancock, Bradley A., Kassem, Nawal, Zhu, Jin, Glasscock, Jarret, Badve, Sunil, Liu, Yunlong, Kesler, Kenneth A., Loehrer, Patrick J., Schneider, Bryan P.

“…Abstract Background: Thymomas & Thymic Carcinomas are rare malignancies with approximately 500 cases in the US per year. Apart from standard chemotherapy,…”
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Abstract 2216: Next-generation whole transcriptome sequencing of triple-negative breast tumors and normal tissues by Radovich, Milan, Clare, Susan E., Pardo, Ivanesa, Hancock, Bradley A., Kassem, Nawal, Sledge, George W., Rufenbarger, Connie, Storniolo, Anna Maria V., Mathieson, Theresa, Sun, Jie, Henry, Jill E., Lillemoe, Heather A., Hilligoss, Eric E., Elliott, James S., Richt, Ryan, Hickenbotham, Matthew, Glasscock, Jarret, Liu, Yunlong, Schneider, Bryan P.

“…Abstract Background: Triple-negative breast cancer (TNBC) disproportionally affects pre-menopausal women and women of African-American descent, and has been…”
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