Search Results - "GJINOVCI, Asllan"

Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds by Campinoti, Sara, Gjinovci, Asllan, Ragazzini, Roberta, Zanieri, Luca, Ariza-McNaughton, Linda, Catucci, Marco, Boeing, Stefan, Park, Jong-Eun, Hutchinson, John C., Muñoz-Ruiz, Miguel, Manti, Pierluigi G., Vozza, Gianluca, Villa, Carlo E., Phylactopoulos, Demetra-Ellie, Maurer, Constance, Testa, Giuseppe, Stauss, Hans J., Teichmann, Sarah A., Sebire, Neil J., Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola

“…The thymus is a primary lymphoid organ, essential for T cell maturation and selection. There has been long-standing interest in processes underpinning thymus…”
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Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration by Urciuolo, Anna, Urbani, Luca, Perin, Silvia, Maghsoudlou, Panagiotis, Scottoni, Federico, Gjinovci, Asllan, Collins-Hooper, Henry, Loukogeorgakis, Stavros, Tyraskis, Athanasios, Torelli, Silvia, Germinario, Elena, Fallas, Mario Enrique Alvarez, Julia-Vilella, Carla, Eaton, Simon, Blaauw, Bert, Patel, Ketan, De Coppi, Paolo

“…Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric muscle loss (VML). Therapeutic approaches involving acellular…”
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Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells by Lorvellec, Maëlle, Scottoni, Federico, Crowley, Claire, Fiadeiro, Rebeca, Maghsoudlou, Panagiotis, Pellegata, Alessandro Filippo, Mazzacuva, Francesca, Gjinovci, Asllan, Lyne, Anne-Marie, Zulini, Justine, Little, Daniel, Mosaku, Olukunbi, Kelly, Deirdre, De Coppi, Paolo, Gissen, Paul

“…Liver transplantation is the definitive treatment of liver failure but donor organ shortage limits its availability. Stem cells are highly expandable and have…”
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β-Cell Secretory Products Activate α-Cell ATP-Dependent Potassium Channels to Inhibit Glucagon Release by FRANKLIN, Isobel, GROMADA, Jesper, GJINOVCI, Asllan, THEANDER, Sten, WOLLHEIM, Claes B

“…β-Cell Secretory Products Activate α-Cell ATP-Dependent Potassium Channels to Inhibit Glucagon Release Isobel Franklin 1 , Jesper Gromada 2 , Asllan Gjinovci 1…”
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Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics by SPEIER, Stephan, GJINOVCI, Asllan, CHAROLLAIS, Anne, MEDA, Paolo, RUPNIK, Marjan

“…Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics Stephan Speier…”
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Dietary Phytoestrogens Activate AMP-Activated Protein Kinase With Improvement in Lipid and Glucose Metabolism by CEDERROTH, Christopher R, VINCIGUERRA, Manlio, DOERGE, Daniel R, WALLIMANN, Theo, MEDA, Paolo, FOTI, Michelangelo, ROHNER-JEANRENAUD, Francoise, VASSALLI, Jean-Dominique, NEF, Serge, GJINOVCI, Asllan, KÜHNE, Francoise, KLEIN, Marcella, CEDERROTH, Manon, CAILLE, Dorothée, SUTER, Mariane, NEUMANN, Dietbert, JAMES, Richard W

“…Dietary Phytoestrogens Activate AMP-Activated Protein Kinase With Improvement in Lipid and Glucose Metabolism Christopher R. Cederroth 1 , Manlio Vinciguerra 2…”
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Loss of Connexin36 Channels Alters β-Cell Coupling, Islet Synchronization of Glucose-Induced Ca2+ and Insulin Oscillations, and Basal Insulin Release by RAVIER, Magalie A, GÜLDENAGEL, Martin, CHAROLLAIS, Anne, GJINOVCI, Asllan, CAILLE, Dorothée, SÖHL, Goran, WOLLHEIM, Claes B, WILLECKE, Klaus, HENQUIN, Jean-Claude, MEDA, Paolo

“…Loss of Connexin36 Channels Alters β-Cell Coupling, Islet Synchronization of Glucose-Induced Ca 2+ and Insulin Oscillations, and Basal Insulin Release Magalie…”
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Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors by Preitner, Frédéric, Ibberson, Mark, Franklin, Isobel, Binnert, Christophe, Pende, Mario, Gjinovci, Asllan, Hansotia, Tanya, Drucker, Daniel J, Wollheim, Claes, Burcelin, Rémy, Thorens, Bernard

“…The role of the gluco-incretin hormones GIP and GLP-1 in the control of beta cell function was studied by analyzing mice with inactivation of each of these…”
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High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets by Lamprianou, Smaragda, Immonen, Riikka, Nabuurs, Christine, Gjinovci, Asllan, Vinet, Laurent, Montet, Xavier C R, Gruetter, Rolf, Meda, Paolo

“…We studied whether manganese-enhanced high-field magnetic resonance (MR) imaging (MEHFMRI) could quantitatively detect individual islets in situ and in vivo…”
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Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival by Martin, David, Allagnat, Florent, Gesina, Emilie, Caille, Dorothee, Gjinovci, Asllan, Waeber, Gerard, Meda, Paolo, Haefliger, Jacques-Antoine

“…The absence of the transcriptional repressor RE-1 Silencing Transcription Factor (REST) in insulin-secreting beta cells is a major cue for the specific…”
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An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies by Lorvellec, Maëlle, Pellegata, Alessandro Filippo, Maestri, Alice, Turchetta, Chiara, Alvarez Mediavilla, Elena, Shibuya, Soichi, Jones, Brendan, Scottoni, Federico, Perocheau, Dany P., Cozmescu, Andrei Claudiu, Delhove, Juliette M., Kysh, Daniel, Gjinovci, Asllan, Counsell, John R., Heywood, Wendy E., Mills, Kevin, McKay, Tristan R., De Coppi, Paolo, Gissen, Paul

“…Explosion of gene therapy approaches for treating rare monogenic and common liver disorders created an urgent need for disease models able to replicate human…”
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Fas pathway is involved in pancreatic β cell secretory function by Schumann, Desiree M, Maedler, Kathrin, Franklin, Isobel, Konrad, Daniel, Størling, Joachim, Böni-Schnetzler, Marianne, Gjinovci, Asllan, Kurrer, Michael O, Gauthier, Benoit R, Bosco, Domenico, Andres, Axel, Berney, Thierry, Greter, Melanie, Becher, Burkhard, Chervonsky, Alexander V, Halban, Philippe A, Mandrup-Poulsen, Thomas, Wollheim, Claes B, Donath, Marc Y

“…Pancreatic β cell mass and function increase in conditions of enhanced insulin demand such as obesity. Failure to adapt leads to diabetes. The molecular…”
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Comparison of Tigecycline and Vancomycin for Treatment of Experimental Foreign-Body Infection Due to Methicillin-Resistant Staphylococcus aureus by VAUDAUX, Pierre, FLEURY, Bénédicte, GJINOVCI, Asllan, HUGGLER, Elzbieta, TANGOMO-BENTO, Manuela, LEW, Daniel P

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Intensive Therapy with Ceftobiprole Medocaril of Experimental Foreign-Body Infection by Methicillin-Resistant Staphylococcus aureus by VAUDAUX, Pierre, GJINOVCI, Asllan, BENTO, Manuela, DONGMEI LI, SCHRENZEL, Jacques, LEW, Daniel P

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Implication of Glutamate in the Kinetics of Insulin Secretion in Rat and Mouse Perfused Pancreas by MAECHLER, Pierre, GJINOVCI, Asllan, WOLLHEIM, Claes B

“…It is intriguing that the kinetics of glucose-stimulated insulin secretion from the in situ perfused pancreas differ between the rat and the mouse. Here we…”
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A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetes by Casimir, Marina, de Andrade, Paula B, Gjinovci, Asllan, Montani, Jean-Pierre, Maechler, Pierre, Dulloo, Abdul G

“…Current notions about mechanisms by which catch-up growth predisposes to later type 2 diabetes center upon those that link hyperinsulinemia with an accelerated…”
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Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase by Iynedjian, P B, Roth, R A, Fleischmann, M, Gjinovci, A

“…Inhibitors of signalling pathways were used to dissect the mechanism of insulin action on expression of the gene encoding glucokinase in cultured rat…”
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Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus by Ragazzini, Roberta, Boeing, Stefan, Zanieri, Luca, Green, Mary, D’Agostino, Giuseppe, Bartolovic, Kerol, Agua-Doce, Ana, Greco, Maria, Watson, Sara A., Batsivari, Antoniana, Ariza-McNaughton, Linda, Gjinovci, Asllan, Scoville, David, Nam, Andy, Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola

“…Thymus is necessary for lifelong immunological tolerance and immunity. It displays a distinctive epithelial complexity and undergoes age-dependent atrophy…”
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Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development by SUPALE, Sachin, THOREL, Fabrizio, MERKWIRTH, Carsten, GJINOVCI, Asllan, HERRERA, Pedro L, SCORRANO, Luca, MEDA, Paolo, LANGER, Thomas, MAECHLER, Pierre

“…Prohibitins are highly conserved proteins mainly implicated in the maintenance of mitochondrial function and architecture. Their dysfunctions are associated…”
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Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors by Urbani, Luca, Camilli, Carlotta, Phylactopoulos, Demetra-Ellie, Crowley, Claire, Natarajan, Dipa, Scottoni, Federico, Maghsoudlou, Panayiotis, McCann, Conor J., Pellegata, Alessandro Filippo, Urciuolo, Anna, Deguchi, Koichi, Khalaf, Sahira, Aruta, Salvatore Ferdinando, Signorelli, Maria Cristina, Kiely, David, Hannon, Edward, Trevisan, Matteo, Wong, Rui Rachel, Baradez, Marc Olivier, Moulding, Dale, Virasami, Alex, Gjinovci, Asllan, Loukogeorgakis, Stavros, Mantero, Sara, Thapar, Nikhil, Sebire, Neil, Eaton, Simon, Lowdell, Mark, Cossu, Giulio, Bonfanti, Paola, De Coppi, Paolo

“…A tissue engineered oesophagus could overcome limitations associated with oesophageal substitution. Combining decellularized scaffolds with patient-derived…”
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