Search Results - "GIVERHAUG, T"
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Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide
Published in European journal of clinical pharmacology (1996)“…Incubation in vitro of human recombinant and erythrocyte (RBC) thiopurine methyl transferase (TPMT) with furosemide, bendroflumethiazide and trichlormethiazide…”
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Low catechol-O-methyltransferase activity in a Saami population
Published in European journal of clinical pharmacology (01-04-1994)“…Catechol-O-methyltransferase (COMT) catalyzes the O-methylation of catechol hormones, neurotransmitters and certain drugs. It is subject to genetic…”
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Intraindividual variability in red blood cell thiopurine methyltransferase activity
Published in European journal of clinical pharmacology (1996)“…Long-term (13 weeks) and circadian (24 hours) intraindividual variability in red blood cell (RBC) thiopurine methyltransferase (TPMT) activity in healthy…”
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Possibilities for therapeutic drug monitoring of azathioprine : 6-thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells
Published in Therapeutic drug monitoring (01-06-1997)“…The objectives of this study were to establish monitoring of azathioprine (AZA) treatment in renal allograft recipients by red blood cell (RBC) 6-thioguanine…”
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Erythrocyte fraction affects red blood cell thiopurine methyltransferase activity
Published in European journal of clinical pharmacology (01-10-1995)“…Red blood cell (RBC) thiopurine methyltransferase (TPMT) metabolizes the cytotoxic drugs 6-mercaptopurine and azathioprine. RBC TPMT activity has been reported…”
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Academic detailing as a method of continuing medical education
Published in Advances in medical education and practice (01-01-2019)“…Academic detailing is an interactive educational outreach to prescribers to present unbiased, non-commercial, evidence-based information, mostly about…”
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A pharmacist-led follow-up program for patients with established coronary heart disease in North Norway – a randomized controlled trial
Published in Pharmacy practice : official journal of the GRIPP (Global Research Institute of Pharmacy Practice) (2015)“…OBJECTIVES: The aim of the study was twofold; 1) to develop a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary…”
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Effectiveness of antihypertensive treatment in chronic renal failure: to what extent and with which drugs do patients treated by nephrologists achieve the recommended blood pressure?
Published in Journal of human hypertension (01-09-2004)“…Adequate control of blood pressure (BP) is important to slow the progression of chronic renal failure (CRF). The Joint National Committee (JNC) VI recommends…”
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Increased Concentrations of Methylated 6-Mercaptopurine Metabolites and 6-Thioguanine Nucleotides in Human Leukemic Cells In Vitro by Methotrexate
Published in Biochemical pharmacology (15-05-1998)“…The effect of methotrexate (MTX) on 6-mercaptopurine (6-MP) metabolism was studied in four human leukemic cell lines in vitro. CCRF-CEM, WI-L2, TBJ, and HL-60…”
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Analysis of methylated 6-mercaptopurine metabolites in human red blood cells : Comparison of two methods
Published in Therapeutic drug monitoring (01-12-1997)“…Blood samples from 34 recipients of kidney transplants who were on multidrug therapy including azathioprine were analyzed using two methods in parallel for red…”
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Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo
Published in Cancer chemotherapy and pharmacology (1997)“…To elucidate the effect of methotrexate (MTX) on 6-mercaptopurine (6-MP) metabolism in rats. Fourteen rats were given 6-MP 20 mg/kg daily for 7 days. Seven of…”
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Secondary prevention in coronary heart disease: goal achievement and drug prescribing
Published in Pharmacy world and science (01-12-2005)“…To provide an overview of the degree of treatment goal achievement and drug prescribing in patients with coronary heart disease (CHD) in clinical practice…”
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The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX)
Published in General pharmacology (01-10-1999)“…The antimetabolites 6-mercaptopurine (6-MP) and methotrexate (MTX) are the cornerstones in the maintenance treatment of children's acute lymphoblastic leukemia…”
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