Search Results - "GIUSTINA, Andrea"

Acromegaly and Bone: An Update by Giustina, Andrea

“…Since our discovery in 2006 that acromegaly is associated with an increased risk of vertebral fractures, many authors have confirmed this finding in both…”
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Vitamin D at the crossroad of prediabetes, sarcopenia, and risk of falls by Giustina, Andrea

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Glucocorticoids and the regulation of growth hormone secretion by Mazziotti, Gherardo, Giustina, Andrea

“…In this Review, Gherardo Mazziotti and Andrea Giustina discuss the latest advances in our understanding of how glucocorticoids affect the secretion of growth…”
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Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions by Bouillon, Roger, Marcocci, Claudio, Carmeliet, Geert, Bikle, Daniel, White, John H, Dawson-Hughes, Bess, Lips, Paul, Munns, Craig F, Lazaretti-Castro, Marise, Giustina, Andrea, Bilezikian, John

“…Abstract The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of 25-hydroxyvitamin D and other metabolites, including…”
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Growth Hormone, Insulin-Like Growth Factors, and the Skeleton by Giustina, Andrea, Mazziotti, Gherardo, Canalis, Ernesto

“…GH and IGF-I are important regulators of bone homeostasis and are central to the achievement of normal longitudinal bone growth and bone mass. Although GH may…”
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Current and Emerging Aspects of Diabetes Mellitus in Acromegaly by Frara, Stefano, Maffezzoni, Filippo, Mazziotti, Gherardo, Giustina, Andrea

“…Diabetes mellitus is a frequent complication of acromegaly, a disease characterized by chronic hypersecretion of growth hormone (GH) by a pituitary adenoma…”
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Growth Hormone, Insulin-Like Growth Factor-1, and the Kidney: Pathophysiological and Clinical Implications by Kamenický, Peter, Mazziotti, Gherardo, Lombès, Marc, Giustina, Andrea, Chanson, Philippe

“…Besides their growth-promoting properties, GH and IGF-1 regulate a broad spectrum of biological functions in several organs, including the kidney. This review…”
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Mechanisms of Anabolic Therapies for Osteoporosis by Canalis, Ernesto, Giustina, Andrea, Bilezikian, John P

“…Antiresorptive agents help to restore skeletal balance by reducing bone turnover, primarily at the tissue level. Another therapeutic approach is to enhance…”
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Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D by Sempos, Christopher T., Heijboer, Annemieke C., Bikle, Daniel D., Bollerslev, Jens, Bouillon, Roger, Brannon, Patsy M., DeLuca, Hector F., Jones, Glenville, Munns, Craig F., Bilezikian, John P., Giustina, Andrea, Binkley, Neil

“…The First International Conference on Controversies in Vitamin D was held in Pisa, Italy, 14–16 June 2017. The meeting's purpose was to address controversies…”
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Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects by Tecilazich, Francesco, Formenti, Anna Maria, Giustina, Andrea

“…Epidemiological data predict a dramatic increase in the prevalence of diabetes and of diabetic retinopathy (DR) – the most common complication of diabetes-for…”
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The role of patient education in the prevention and management of type 2 diabetes: an overview by Coppola, Adriana, Sasso, Loredana, Bagnasco, Annamaria, Giustina, Andrea, Gazzaruso, Carmine

“…The management of type 2 diabetes mellitus includes ability and empowerment of the patient to change lifestyle, maintain an adequate diet and physical…”
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Clinical Biology of the Pituitary Adenoma by Melmed, Shlomo, Kaiser, Ursula B, Lopes, M Beatriz, Bertherat, Jerome, Syro, Luis V, Raverot, Gerald, Reincke, Martin, Johannsson, Gudmundur, Beckers, Albert, Fleseriu, Maria, Giustina, Andrea, Wass, John A H, Ho, Ken K Y

“…Abstract All endocrine glands are susceptible to neoplastic growth, yet the health consequences of these neoplasms differ between endocrine tissues. Pituitary…”
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Meta-analysis on the effects of octreotide on tumor mass in acromegaly by Giustina, Andrea, Mazziotti, Gherardo, Torri, Valter, Spinello, Maurizio, Floriani, Irene, Melmed, Shlomo

“…The long-acting somatostatin analogue octreotide is used either as an adjuvant or primary therapy to lower growth hormone (GH) levels in patients with…”
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A Pituitary Society update to acromegaly management guidelines by Fleseriu, Maria, Biller, Beverly M. K., Freda, Pamela U., Gadelha, Monica R., Giustina, Andrea, Katznelson, Laurence, Molitch, Mark E., Samson, Susan L., Strasburger, Christian J., van der Lely, A. J., Melmed, Shlomo

“…Guidelines and consensus statements ensure that physicians managing acromegaly patients have access to current information on evidence-based treatments to…”
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Drug-induced Osteoporosis: Mechanisms and Clinical Implications by Mazziotti, Gherardo, MD, PhD, Canalis, Ernesto, MD, Giustina, Andrea, MD

“…Abstract Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering from chronic debilitating diseases…”
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Novel protective circulating miRNA are associated with preserved vitamin D levels in patients with mild COVID-19 presentation at hospital admission not progressing into severe disease by di Filippo, Luigi, Terenzi, Umberto, Di Ienno, Giovanni, Trasciatti, Silvia, Bonaretti, Silvano, Giustina, Andrea

“…Purpose Low vitamin D levels were reported to negatively influence the outcomes of acute COVID-19, as well as other biochemical markers were linked to…”
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Effects of Somatostatin Analogs on Glucose Homeostasis: A Metaanalysis of Acromegaly Studies by Mazziotti, Gherardo, Floriani, Irene, Bonadonna, Stefania, Torri, Valter, Chanson, Philippe, Giustina, Andrea

“…Background: Somatostatin analogs (SSA) may influence glucose metabolism, but the clinical relevance of this effect is uncertain because trials performed so far…”
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Adiponectin to leptin ratio reflects inflammatory burden and survival in COVID-19 by Di Filippo, Luigi, De Lorenzo, Rebecca, Sciorati, Clara, Capobianco, Annalisa, Lorè, Nicola I., Giustina, Andrea, Manfredi, Angelo A., Rovere-Querini, Patrizia, Conte, Caterina

“…Obesity is a risk factor for COVID-19, but the underlying mechanisms are unclear. We investigated the role of adiponectin (an anti-inflammatory adipokine),…”
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Vitamin D in Osteosarcopenic Obesity by Di Filippo, Luigi, De Lorenzo, Rebecca, Giustina, Andrea, Rovere-Querini, Patrizia, Conte, Caterina

“…Osteosarcopenic obesity is a unique clinical condition where low bone and muscle mass coexist in individuals with obesity. Alterations in adipose tissue,…”
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Glucocorticoid-induced osteoporosis: pathophysiological role of GH/IGF-I and PTH/VITAMIN D axes, treatment options and guidelines by Mazziotti, Gherardo, Formenti, Anna Maria, Adler, Robert A., Bilezikian, John P., Grossman, Ashley, Sbardella, Emilia, Minisola, Salvatore, Giustina, Andrea

“…Glucocorticoid-induced osteoporosis is the most frequent form of secondary osteoporosis caused by chronic exposure to glucocorticoid excess. Pathogenesis of…”
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