Search Results - "GIRDLESTONE, J."

Differential cytokine expression in direct and indirect co-culture of islets and mesenchymal stromal cells by Dietrich, I., Girdlestone, J., Giele, H.

“…Transplantation of allogenic Langerhans islets (ISL) has been employed as an alternative to pancreas transplantation to provide endogenous supply of insulin…”
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Transitional B Lymphocytes Are Associated With Protection From Kidney Allograft Rejection: A Prospective Study by Shabir, S., Girdlestone, J., Briggs, D., Kaul, B., Smith, H., Daga, S., Chand, S., Jham, S., Navarrete, C., Harper, L., Ball, S., Borrows, R.

“…Recent cross‐sectional studies suggest an important role for transitional B lymphocytes (CD19 + CD24hiCD38hi) in promoting transplant tolerance, and protecting…”
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Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease by TISATO, V, NARESH, K, GIRDLESTONE, J, NAVARRETE, C, DAZZI, F

“…The immunosuppressive properties of mesenchymal stem cells (MSC) make them particularly attractive to manipulate graft-versus-host disease (GVHD). So far, the…”
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5-Azacytidine-treated human mesenchymal stem/progenitor cells derived from umbilical cord, cord blood and bone marrow do not generate cardiomyocytes in vitro at high frequencies by Martin-Rendon, E., Sweeney, D., Lu, F., Girdlestone, J., Navarrete, C., Watt, S. M.

“…Background and Objectives  Mesenchymal stem/progenitor cells (MSCs) are multipotent progenitors that differentiate into such lineages as bone, fat, cartilage…”
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Characterization of mesenchymal stromal cells derived from full-term umbilical cord blood by Manca, M.F, Zwart, I, Beo, J, Palasingham, R, Jen, L.-S, Navarrete, R, Girdlestone, J, Navarrete, C.V

“…Background Multipotent mesenchymal stromal cells (MSC) are of interest for their potential to repair bone and cartilage, and also their immunosuppressive…”
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Fractalkine expression on human renal tubular epithelial cells: potential role in mononuclear cell adhesion by CHAKRAVORTY, S. J., COCKWELL, P., GIRDLESTONE, J., BROOKS, C. J., SAVAGE, C. O. S.

“…SUMMARY Fractalkine (CX3CL1) is a transmembrane molecule with a CX3C chemokine domain attached to an extracellular mucin stalk which can induce both adhesion…”
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Nucleotide sequence of an HLA-A1 gene by GIRDLESTONE, J

“…I report here the complete genomic sequence of the HLA-A1 gene from the human thymoma line MOLT4, which has been serologically typed as A1, A3, Bw57, B18. The…”
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Transcriptional Regulation of HLA-A and -B: Differential Binding of Members of the Rel and IRF Families of Transcription Factors by Girdlestone, John, Isamat, Marcos, Gewert, Dirk, Milstein, Cesar

“…HLA-A and -B transplantation antigens can be expressed differentially at the basal level and in response to interferons (IFNs). To determine which DNA control…”
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Transitional (Regulatory) B Cells Are Associated With Biopsy Proven Rejection Episodes Following Kidney Transplantation: Abstract# 2904 by Shabir, S., Girdlestone, J., McCloskey, M., Huhn, L., Horgan, P., Ball, S., Borrows, R.

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Nucleotide sequence of an HLA-Bw57 gene by ISAMAT, M, GIRDLESTONE, J, MILSTEIN, C

“…We report here the complete genomic sequence of the HLA-Bw57 gene from the human thymoma line MOLT4, which has been serologically typed as A1, A10, B17 (Bw57),…”
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Building capacity for service user and carer involvement in research: the implications and impact of best research for best health by Minogue, Virginia, Girdlestone, John

“…The purpose of this paper is to examine the role of service user and carer involvement in NHS research and describe the nature of this involvement in three…”
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Synergistic induction of HLA class I expression by RelA and CIITA by GIRDLESTONE, J

“…The major histocompatibility complex (MHC) class I genes are induced synergistically by interferons (IFN) and tumor necrosis factor (TNF), a response thought…”
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Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection by Altare, F, Lammas, D, Revy, P, Jouanguy, E, Döffinger, R, Lamhamedi, S, Drysdale, P, Scheel-Toellner, D, Girdlestone, J, Darbyshire, P, Wadhwa, M, Dockrell, H, Salmon, M, Fischer, A, Durandy, A, Casanova, J L, Kumararatne, D S

“…Interferon-gamma receptor ligand-binding chain (IFN-gammaR1) or signaling chain (IFN-gammaR2) deficiency, like interleukin 12 receptor beta1 chain…”
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A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection by Lammas, David, Dorman, Susan E, Altare, Frédéric, Edgar, David, Novelli, Vas, Heyne, Klaus, Holland, Steven M, Casanova, Jean-Laurent, Fondanèche, Marie-Claude, Dupuis, Stéphanie, Clarke, Jane, Lamhamedi-Cherradi, Salma, Fischer, Alain, Kumararatne, Dinakantha S, Ducoulombier, Henri, Emile, Jean-François, Schreiber, Robert D, Girdlestone, John, Jouanguy, Emmanuelle, Döffinger, Rainer, Oxelius, Vivi-Anne, Brai, Melchiorre

“…The immunogenetic basis of severe infections caused by bacille Calmette-Guérin vaccine and environmental mycobacteria in humans remains largely unknown. We…”
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Fractalkine expression in human renal inflammation by Cockwell, Paul, Chakravorty, Srabasti J., Girdlestone, John, Savage, Caroline O. S.

“…Immune and inflammatory human renal disease is associated with heavy mononuclear cell infiltration. The trafficking of these cells to extravascular sites is…”
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Interferon‐β mediates stromal cell rescue of T cells from apoptosis by Pilling, Darrell, Akbar, Arne N., Girdlestone, John, Orteu, Catherine H., Borthwick, Nicola J., Amft, Nicole, Scheel‐Toellner, Dagmar, Buckley, Christopher D., Salmon, Mike

“…The resolution of immune responses is characterized by extensive apoptosis of activated T cells. However, to generate and maintain immunological memory, some…”
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Positive Cooperativity in a (Dissected) Lectin-Membrane Glycoprotein Binding Event by Ketis, Nika V., Girdlestone, John, Chris W. M. Grant

“…A transmembrane glycoprotein, glycophorin, was assembled into large liposomes that may be handled like intact cells. Under appropriate conditions, lectin…”
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Regulation of HLA Class I Loci by Interferons by Girdlestone, John

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Autocrine activation by interferon-gamma of STAT factors following T cell activation by Girdlestone, J, Wing, M

“…The activation of T cells requires engagement of the T cell receptor/CD3 complex and co-stimulatory molecules, and results in the triggering of several…”
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An HLA-B regulatory element binds a factor immunologically related to the upstream stimulation factor by GIRDLESTONE, J

“…HLA-A and -B are expressed by most cell types, and their levels can be increased by treatment with interferons (IFNs). The relative basal levels of HLA-A and…”
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