Search Results - "GIRAUD, G. D"

Cortisol Stimulates Cell Cycle Activity in the Cardiomyocyte of the Sheep Fetus by Giraud, G. D, Louey, S, Jonker, S, Schultz, J, Thornburg, K. L

“…The role of cortisol in regulating cardiac myocyte growth in the near-term fetal sheep is unknown. We hypothesized that cortisol would suppress cardiomyocyte…”
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Thyroid hormone inhibits proliferation of fetal cardiac myocytes in vitro by Chattergoon, N N, Giraud, G D, Thornburg, K L

“…Thyroid hormone (T3) is a key regulator of fetal organ maturation. Premature elevations of thyroid hormone may lead to a ‘mature’ cardio-phenotype. Thyroid…”
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Atrial natriuretic peptide inhibits angiotensin II‐stimulated proliferation in fetal cardiomyocytes by O’Tierney, P. F., Chattergoon, N. N., Louey, S., Giraud, G. D., Thornburg, K. L.

“…The role of atrial natriuretic peptide (ANP) in regulating fetal cardiac growth is poorly understood. Angiotensin II (Ang II) stimulates proliferation in fetal…”
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Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes by Sundgren, N C, Giraud, G D, Stork, P J S, Maylie, J G, Thornburg, K L

“…Rat and sheep cardiac myocytes become binucleate as they complete the ‘terminal differentiation’ process soon after birth and are not able to divide…”
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Insignificant response of the fetal placental circulation to arterial hypotension in sheep by FABER, J. J, ANDERSON, D. F, LOUEY, S, THORNBURG, K. L, GIRAUD, G. D

“…Infusion of the angiotensin-converting enzyme inhibitor enalaprilat into fetal sheep caused a profound arterial hypotension within days. Five fetal lambs were…”
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The effects of anaemia as a programming agent in the fetal heart by Davis, L., Thornburg, K. L., Giraud, G. D.

“…The intrauterine environment plays a powerful role in determining the life-long risk of cardiovascular disease. A number of stressors are well known to affect…”
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Right ventricular systolic pressure load alters myocyte maturation in fetal sheep by Barbera, A, Giraud, G D, Reller, M D, Maylie, J, Morton, M J, Thornburg, K L

“…The effects of right ventricular (RV) systolic pressure (RVSP) load on fetal myocyte size and maturation were studied. Pulmonary artery (PA) pressure was…”
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Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep by Yang, Q, Hohimer, A.R, Giraud, G.D, Van Winkle, D.M, Underwood, M.J, He, G.-W, Davis, L.E

“…We investigated whether chronic fetal anaemia affects myocardial infarct in adulthood and elicits functional modifications in adult coronary vasoreactivity…”
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Augmentation of coronary conductance in adult sheep made anaemic during fetal life by Davis, L, Roullet, J B, Thornburg, K L, Shokry, M, Hohimer, A R, Giraud, G D

“…Maximal coronary conductance with adenosine in anaemic fetal sheep is twice that of non-anaemic fetuses. To investigate whether this increase in conductance…”
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Nasal contribution to exhaled nitric oxide at rest and during breathholding in humans by Kimberly, B, Nejadnik, B, Giraud, G D, Holden, W E

“…We characterized the nasal contribution to exhaled nitric oxide (NO) at rest and during breathholding in humans. Exhaled NO was greater during nose breathing…”
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Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes by Chattergoon, N N, Louey, S, Stork, P J, Giraud, G D, Thornburg, K L

“…In the first two-thirds of gestation, ovine fetal cardiomyocytes undergo mitosis to increase cardiac mass and accommodate fetal growth. Thereafter, some…”
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Exhaled nitric oxide during exercise: site of release and modulation by ventilation and blood flow by Phillips, C R, Giraud, G D, Holden, W E

“…To define the site of release and factors modulating exhaled nitric oxide (NO) during exercise in humans, we measured exhaled NO output during exercise, during…”
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Fetal Infusions of Plasma Cause an Increase in Umbilical Vascular Resistance in Sheep by Faber, J.J., Anderson, D.F., Jonker, S.S., Davis, L.E., Giraud, G.D.

“…Earlier studies suggested that the fetal placental circulation is relatively inert with fetal placental flow increasing or decreasing with perfusion pressure…”
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Anaemia stimulates aquaporin 1 expression in the fetal sheep heart by Jonker, S. S., Davis, L. E., Bilt, J. D. W. van der, Hadder, B., Hohimer, A. R., Giraud, G. D., Thornburg, K. L.

“…Interstitial fluid fluxes are much greater in the fetus than in the adult, and filtration rates are increased over control in most tissues of the anaemic…”
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Reduced systolic pressure load decreases cell-cycle activity in the fetal sheep heart by O'Tierney, P F, Anderson, D F, Faber, J J, Louey, S, Thornburg, K L, Giraud, G D

“…The fetal heart is highly sensitive to changes in mechanical load. We have previously demonstrated that increased cardiac load can stimulate cell cycle…”
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Decreased exhaled nitric oxide in subjects with HIV infection by Loveless, M O, Phillips, C R, Giraud, G D, Holden, W E

“…BACKGROUND: Nitric oxide (NO) may be an important component of the host defence against infections. Endogenously produced NO is present in exhaled air and may…”
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Temperature conditioning of nasal air: effects of vasoactive agents and involvement of nitric oxide by Holden, William E, Wilkins, John P, Harris, Michelle, Milczuk, Henry A, Giraud, George D

“…1  Medical Service, Portland Veterans Affairs Medical Center, and 2  Department of Otolaryngology, Oregon Health Sciences University, Portland, Oregon 97201…”
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Does nitric oxide contribute to the basal vasodilation of pregnancy in conscious rabbits? by Brooks, V L, Clow, K A, Welch, L S, Giraud, G D

“…Pregnancy produces marked systemic vasodilation, but the mechanism is unknown. Experiments were performed in conscious rabbits to test the hypotheses that…”
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Maximal myocardial blood flow is enhanced by chronic hypoxemia in late gestation fetal sheep by Reller, M D, Morton, M J, Giraud, G D, Wu, D E, Thornburg, K L

“…The measurement of maximal myocardial blood flow gives information about the total cross-sectional area of the coronary resistance vessels. During a continuous…”
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Nasal administration of the nitric oxide synthase inhibitor L-NAME induces daytime somnolence by SIPPEL, J. M, GIRAUD, G. D, HOLDEN, W. E

“…In preliminary studies, human subjects complained of drowsiness after aerosolization of NG-nitro-L-arginine methyl ester (L-NAME) into the nasal passages. We…”
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