Search Results - "GIORGI, Luigi"

Lemborexant, A Dual Orexin Receptor Antagonist (DORA) for the Treatment of Insomnia Disorder: Results From a Bayesian, Adaptive, Randomized, Double-Blind, Placebo-Controlled Study by Murphy, Patricia, Moline, Margaret, Mayleben, David, Rosenberg, Russell, Zammit, Gary, Pinner, Kate, Dhadda, Shobha, Hong, Quan, Giorgi, Luigi, Satlin, Andrew

“…To identify dose(s) of lemborexant that maximize insomnia treatment efficacy while minimizing next-morning residual sleepiness and evaluate lemborexant effects…”
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Efficacy and tolerability of zonisamide versus controlled-release carbamazepine for newly diagnosed partial epilepsy: a phase 3, randomised, double-blind, non-inferiority trial by Baulac, Michel, Prof, Brodie, Martin J, Prof, Patten, Anna, PhD, Segieth, Joanna, PhD, Giorgi, Luigi, MD

“…Summary Background Additional options are needed for monotherapy treatment of adults newly diagnosed with partial epilepsy. This trial compares the efficacy…”
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Duration of response after DEB-TACE compared to lipiodol-TACE in HCC-naïve patients: a propensity score matching analysis by Bargellini, Irene, Lorenzoni, Valentina, Lorenzoni, Giulia, Scalise, Paola, Andreozzi, Gianni, Bozzi, Elena, Giorgi, Luigi, Cervelli, Rosa, Scandiffio, Rossella, Perrone, Orsola, Meccia, Donato Vito, Boccuzzi, Antonio, Daviddi, Francesco, Cicorelli, Antonio, Lunardi, Alessandro, Crocetti, Laura, Turchetti, Giuseppe, Cioni, Roberto

“…Objectives To retrospectively compare long-term outcomes of first-line drug-eluting particle (DEB)- transarterial chemoembolization (TACE) and lipiodol-TACE,…”
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Updated safety results from phase 3 lecanemab study in early Alzheimer's disease by Honig, Lawrence S, Sabbagh, Marwan N, van Dyck, Christopher H, Sperling, Reisa A, Hersch, Steven, Matta, Andre, Giorgi, Luigi, Gee, Michelle, Kanekiyo, Michio, Li, David, Purcell, Derk, Dhadda, Shobha, Irizarry, Michael, Kramer, Lynn

“…Alzheimer disease (AD) is a major health problem of aging, with tremendous burden on healthcare systems, patients, and families globally. Lecanemab, an…”
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PREPARED: Comparison of prolonged and immediate release ropinirole in advanced Parkinson's disease by Stocchi, Fabrizio, Giorgi, Luigi, Hunter, Brian, Schapira, Anthony HV

“…Background: PREPARED was a randomized, parallel‐group, double‐blind, multicenter study to evaluate the efficacy of adjunctive ropinirole prolonged release (PR)…”
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Correction: Updated safety results from phase 3 lecanemab study in early Alzheimer's disease by Honig, Lawrence S, Sabbagh, Marwan N, van Dyck, Christopher H, Sperling, Reisa A, Hersch, Steven, Matta, Andre, Giorgi, Luigi, Gee, Michelle, Kanekiyo, Michio, Li, David, Purcell, Derk, Dhadda, Shobha, Irizarry, Michael, Kramer, Lynn

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CIRSE Guidelines on Percutaneous Needle Biopsy (PNB) by Veltri, Andrea, Bargellini, Irene, Giorgi, Luigi, Almeida, Paulo Alexandre Matos Silva, Akhan, Okan

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Spontaneous Bleedings in COVID-19 Patients: An Emerging Complication by Bargellini, Irene, Cervelli, Rosa, Lunardi, Alessandro, Scandiffio, Rossella, Daviddi, Francesco, Giorgi, Luigi, Cicorelli, Antonio, Crocetti, Laura, Cioni, Roberto

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Ropinirole in Patients With Restless Legs Syndrome and Baseline IRLS Total Scores ≥24: Efficacy and Tolerability in a 26-Week, Double-Blind, Parallel-Group, Placebo-Controlled Study Followed by a 40-Week Open-Label Extension by Giorgi, Luigi, MD, Asgharian, Afsaneh, MS, Hunter, Brian, PhD

“…Abstract Background As with studies of other dopamine agonists, previously reported studies of ropinirole in restless legs syndrome (RLS) recruited patients…”
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Spontaneous Bleedings in COVID-19 Patients: An Emerging Complication by Bargellini, Irene, Cervelli, Rosa, Lunardi, Alessandro, Scandiffio, Rossella, Daviddi, Francesco, Giorgi, Luigi, Cicorelli, Antonio, Crocetti, Laura, Cioni, Roberto

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Long‐term safety and efficacy of zonisamide versus carbamazepine monotherapy for treatment of partial seizures in adults with newly diagnosed epilepsy: Results of a phase III, randomized, double‐blind study by Baulac, Michel, Patten, Anna, Giorgi, Luigi

“…Summary Objective To investigate the long‐term safety and maintenance of efficacy of monotherapy with once‐daily zonisamide versus twice‐daily…”
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The tolerability of lamotrigine in children by MESSENHEIMER, J. A, GIORGI, L, RISNER, M. E

“…Lamotrigine is a novel anticonvulsant, which has proven to be effective both as add-on and monotherapy. 13 studies have demonstrated efficacy in 1096 children…”
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Impact of Clinical Subgroup and Baseline Amyloid PET Centiloid Levels on Occurrence of ARIA in the Lecanemab Phase 3 Clarity AD Study in Early Alzheimer’s Disease (P1-9.007) by Sabbagh, Marwan, Li, David, Dhadda, Shobha, Hersch, Steven, Giorgi, Luigi, Matta, Andre, Irizarry, Michael, Kramer, Lynn

“…Abstract only…”
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Adjunctive zonisamide therapy in the long‐term treatment of children with partial epilepsy: Results of an open‐label extension study of a phase III, randomized, double‐blind, placebo‐controlled trial by Guerrini, Renzo, Rosati, Anna, Bradshaw, Kate, Giorgi, Luigi

“…Summary Objective To investigate the safety/tolerability and efficacy of long‐term adjunctive zonisamide and its impact on growth and development in children…”
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A randomized phase III trial of adjunctive zonisamide in pediatric patients with partial epilepsy by Guerrini, Renzo, Rosati, Anna, Segieth, Joanna, Pellacani, Simona, Bradshaw, Kate, Giorgi, Luigi

“…Summary Purpose To assess the efficacy and safety/tolerability of adjunctive zonisamide treatment in pediatric patients with partial epilepsy. Methods In this…”
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First‐in‐Human (FIH), Single‐ and Multiple‐Ascending‐Dose (SAD/MAD) studies in healthy subjects of E2511, a novel tropomyosin receptor kinase a (TrkA) positive allosteric modulator (PAM) by Aceves, Pau, Hall, Nancy, Dayal, Satish, Yagi, Takuya, Chang, Julia, Mikamoto, Masaki, Ringheim, Garth E, Takesuya, Tomioka, Hiramatsu, Naoki, Gordon, Robert, Giorgi, Luigi

“…Background Cholinergic innervation is affected in multiple neurodegenerative diseases associated with cognitive dysfunction. Loss of cholinergic neurons in…”
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Thermal Hydraulics of Accelerator-Driven System Windowless Targets by Panella, Bruno, De Giorgi, Luigi Consalvo, De Salve, Mario, Bertani, Cristina, Malandrone, Mario

“…The study of the fluid dynamics of the windowless spallation target of an Accelerator Driven System (ADS) is presented. Several target mockup configurations…”
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Transarterial radioembolization for hepatocellular carcinoma: An update and perspectives by Sacco, Rodolfo, Mismas, Valeria, Marceglia, Sara, Romano, Antonio, Giacomelli, Luca, Bertini, Marco, Federici, Graziana, Metrangolo, Salvatore, Parisi, Giuseppe, Tumino, Emanuele, Bresci, Giampaolo, Corti, Ambra, Tredici, Manuel, Piccinno, Michele, Giorgi, Luigi, Bartolozzi, Carlo, Bargellini, Irene

“…In the last decade trans-arterial radioembolization has given promising results in the treatment of patients with intermediate or advanced stage hepatocellular…”
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LONG-TERM SAFETY AND EFFICACY OF ZONISAMIDE VERSUS CARBAMAZEPINE MONOTHERAPY FOR TREATMENT OF PARTIAL SEIZURES IN ADULTS WITH NEWLY DIAGNOSED EPILEPSY: RESULTS OF A PHASE III, MULTINATIONAL, RANDOMISED, DOUBLE-BLIND, ACTIVE-CONTROLLED STUDY by Baulac, Michel, Bagul, Makarand, Patten, Anna, Giorgi, Luigi

“…PurposeTo assess the long-term safety and efficacy of zonisamide versus carbamazepine monotherapy for partial seizures in adults with newly diagnosed…”
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Trans-Arterial Radioembolization for Hepatocellular Carcinoma by Sacco, Rodolfo, Giorgi, Luigi, Fornaro, Lorenzo, Bargellini, Irene

“…This article offers an overview of a new therapeutic option in hepatocellular carcinoma using trans-arterial radioembolization. In particular, it covers…”
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