Search Results - "GIORDANO ATTIANESE, Greta Maria Paola"

Coengineering specificity, safety, and function into T cells for cancer immunotherapy by Giordano Attianese, Greta Maria Paola, Ash, Sarah, Irving, Melita

“…Adoptive T-cell transfer (ACT) therapies, including of tumor infiltrating lymphocytes (TILs) and T cells gene-modified to express either a T cell receptor…”
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Hemicentin 1 influences podocyte dynamic changes in glomerular diseases by Toffoli, Barbara, Zennaro, Cristina, Winkler, Carine, Giordano Attianese, Greta Maria Paola, Bernardi, Stella, Carraro, Michele, Gilardi, Federica, Desvergne, Béatrice

“…Different complex mechanisms control the morphology of podocyte foot processes and their interactions with the underlying basement membrane. Injuries to this…”
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Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors by MARIN, Virna, PIZZITOLA, Irene, AGOSTONI, Valentina, GIORDANO ATTIANESE, Greta Maria Paola, FINNEY, Helene, LAWSON, Alastair, PULE, Martin, ROUSSEAU, Raphael, BIONDI, Andrea, BIAGI, Ettore

“…Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute…”
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Magnesium sensing via LFA-1 regulates CD8+ T cell effector function by Lötscher, Jonas, Martí i Líndez, Adrià-Arnau, Kirchhammer, Nicole, Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Trefny, Marcel P., Lenz, Markus, Rothschild, Sacha I., Strati, Paolo, Künzli, Marco, Lotter, Claudia, Schenk, Susanne H., Dehio, Philippe, Löliger, Jordan, Litzler, Ludivine, Schreiner, David, Koch, Victoria, Page, Nicolas, Lee, Dahye, Grählert, Jasmin, Kuzmin, Dmitry, Burgener, Anne-Valérie, Merkler, Doron, Pless, Miklos, Balmer, Maria L., Reith, Walter, Huwyler, Jörg, Irving, Melita, King, Carolyn G., Zippelius, Alfred, Hess, Christoph

“…The relevance of extracellular magnesium in cellular immunity remains largely unknown. Here, we show that the co-stimulatory cell-surface molecule LFA-1…”
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CAR T cells targeting the ganglioside NGcGM3 control ovarian tumors in the absence of toxicity against healthy tissues by Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Coukos, George, Irving, Melita

“…Chimeric antigen receptor (CAR) T cells have emerged as a powerful immunotherapeutic tool against certain hematological malignancies but a significant…”
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Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion by Sardella, Chiara, Winkler, Carine, Quignodon, Laure, Hardman, Jonathan A., Toffoli, Barbara, Giordano Attianese, Greta Maria Paola, Hundt, Jennifer E., Michalik, Liliane, Vinson, Charles R., Paus, Ralf, Desvergne, Béatrice, Gilardi, Federica

“…PPARγ regulates multiple aspects of skin physiology, including sebocyte differentiation, keratinocyte proliferation, epithelial stem cell survival, adipocyte…”
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Chimeric T-cell receptors: new challenges for targeted immunotherapy in hematologic malignancies by Biagi, Ettore, Marin, Virna, Giordano Attianese, Greta Maria Paola, Dander, Erica, D'Amico, Giovanna, Biondi, Andrea

“…"Centro di Ricerca Matilde Tettamanti", Department of Paediatrics, University of Milano-Bicocca, San Gerardo Hospital, Monza, Milan, Italy. Correspondence:…”
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Lenalidomide enhances CD23.CAR T cell therapy in chronic lymphocytic leukemia by Tettamanti, Sarah, Rotiroti, Maria Caterina, Giordano Attianese, Greta Maria Paola, Arcangeli, Silvia, Zhang, Ronghua, Banerjee, Priyanka, Galletti, Giovanni, McManus, Sheighlah, Mazza, Massimiliano, Nicolini, Fabio, Martinelli, Giovanni, Ivan, Cristina, Veliz Rodriguez, Tania, Barbaglio, Federica, Scarfò, Lydia, Ponzoni, Maurilio, Wierda, William, Gandhi, Varsha, Keating, Michael, Biondi, Andrea, Caligaris-Cappio, Federico, Biagi, Ettore, Ghia, Paolo, Bertilaccio, Maria Teresa Sabrina

“…Chimeric antigen receptors (CAR)-modified T cells are an emerging therapeutic tool for chronic lymphocytic leukemia (CLL). However, in patients with CLL,…”
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Enforcing GLUT3 expression in CD8 + T cells improves fitness and tumor control by promoting glucose uptake and energy storage by Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Ginefra, Pierpaolo, Signorino-Gelo, Amandine, Vuillefroy de Silly, Romain, Vannini, Nicola, Hess, Christoph, Irving, Melita, Coukos, George

“…Despite the tremendous success of adoptive T-cell therapies (ACT) in fighting certain hematologic malignancies, not all patients respond, a proportion…”
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In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor by Giordano Attianese, Greta Maria Paola, Marin, Virna, Hoyos, Valentina, Savoldo, Barbara, Pizzitola, Irene, Tettamanti, Sarah, Agostoni, Valentina, Parma, Matteo, Ponzoni, Maurilio, Bertilaccio, Maria T.S., Ghia, Paolo, Biondi, Andrea, Dotti, Gianpietro, Biagi, Ettore

“…Chronic lymphocytic leukemia (CLL) is characterized by an accumulation of mature CD19+CD5+CD20dim B lymphocytes that typically express the B-cell activation…”
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A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD+ metabolism by Maric, Tamara, Bazhin, Arkadiy, Khodakivskyi, Pavlo, Mikhaylov, Georgy, Solodnikova, Ekaterina, Yevtodiyenko, Aleksey, Giordano Attianese, Greta Maria Paola, Coukos, George, Irving, Melita, Joffraud, Magali, Cantó, Carles, Goun, Elena

“…Nicotinamide riboside (NR) is a form of vitamin B3 and is one of the most studied compounds for the restoration of cellular NAD+ levels demonstrating clinical…”
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Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs by Giordano Attianese, Greta Maria Paola, Shui, Sailan, Cribioli, Elisabetta, Triboulet, Melanie, Scheller, Leo, Hafezi, Morteza, Reichenbach, Patrick, Gainza, Pablo, Georgeon, Sandrine, Correia, Bruno E, Irving, Melita

“…The ability to remotely control the activity of chimeric antigen receptors (CARs) with small molecules can improve the safety and efficacy of gene-modified T…”
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A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor by Reichenbach, Patrick, Giordano Attianese, Greta Maria Paola, Ouchen, Khaoula, Cribioli, Elisabetta, Triboulet, Melanie, Ash, Sarah, Saillard, Margaux, Vuillefroy de Silly, Romain, Coukos, George, Irving, Melita

“…Vectors that facilitate the engineering of T cells that can better harness endogenous immunity and overcome suppressive barriers in the tumour microenvironment…”
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Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells by Magnani, Chiara Francesca, Turazzi, Nice, Benedicenti, Fabrizio, Paola Giordano Attianese, Greta Maria, Tettamanti, Sarah, Montini, Eugenio, Cooper, Laurence J N, Aiuti, Alessandro, Biondi, Andrea, Biagi, Ettore

“…Gene-manipulation of effector T cells with CARs has recently turned into a powerful tool to redirect antigen specificity for adoptive immunotherapy of tumors…”
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Targeting of Acute Myeloid Leukemia by Cytokine-Induced Killer Cells Redirected with a Novel CD123-Specific Chimeric Antigen Receptor by Tettamanti, Sarah, Marin, Virna, Pizzitola, Irene, Magnani, Chiara Francesca, Attianese, Greta Maria Paola Giordano, Cribioli, Elisabetta, Lopez, Angel, Biondi, Andrea, Bonnet, Dominique, Biagi, Ettore

“…Abstract 3010 Current therapeutic regimens for Acute Myeloid Leukemia (AML) are still associated with high rates of relapse. In the last years, great interest…”
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Low-Dose Lenalidomide Improves CAR-Based Immunotherapy In CLL By Reverting T-Cell Defects In Vivo by Sabrina Bertilaccio, Maria Teresa, Tettamanti, Sarah, Giordano Attianese, Greta Maria Paola, Galletti, Giovanni, Arcangeli, Silvia, Rodriguez, Tania Veliz, Magnani, Chiara Francesca, Barbaglio, Federica, Scarfò, Lydia, Ponzoni, Maurilio, Biondi, Andrea, Caligaris-Cappio, Federico, Biagi, Ettore, Ghia, Paolo

“…Chronic Lymphocytic Leukemia (CLL) is a chronic lymphoid malignancy characterized by immune suppression that is responsible for an increase in infection…”
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A New Chimeric Antigen Receptor (CAR) Targeting the CD23 Antigen Expressed by Chronic Lymphocytic Leukemia (B-CLL) Cells by Attianese, Greta Maria Paola Giordano, Hoyos, Valentina, Marin, Virna, Savoldo, Barbara, Pizzitola, Irene, Agostoni, Valentina, Parma, Matteo, Bertilaccio, Maria Teresa Sabrina, Ghia, Paolo, Biondi, Andrea, Dotti, Gianpietro, Biagi, Ettore

“…Abstract 2446 B-Chronic lymphocytic leukemia (B-CLL) is characterized by a progressive accumulation of B-lymphocytes expressing CD19, CD20dim and aberrantly…”
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Generation of a New Chimeric Antigen Receptor (CAR) to Target CD23 Expressed on Chronic Lymphocytic Leukemia (B-CLL) Cells by Attianese, Greta Maria Paola Giordano, Hoyos, Valentina, Savoldo, Barbara, Marin, Virna, Brandi, Malika, Biondi, Andrea, Biagi, Ettore, Dotti, Gianpietro

“…B-Chronic lymphocytic leukemia (B-CLL) is characterized by a progressive accumulation of mature B-lymphocytes expressing CD19, CD20dim and aberrantly…”
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New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future by Biagi, Ettore, Marin, Virna, Attianese, Greta Maria Paola Giordano, Pizzitola, Irene, Tettamanti, Sarah, Cribioli, Elisabetta, Biondi, Andrea

“…Leukaemia immunotherapy represents a fascinating and promising field of translational research, particularly as an integrative approach of bone marrow…”
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