Search Results - "GINGERAS, T. R"

Mycobacterium Species Identification and Rifampin Resistance Testing with High-Density DNA Probe Arrays by TROESCH, A, NGUYEN, H, MIYADA, C. G, DESVARENNE, S, GINGERAS, T. R, KAPLAN, P. M, CROS, P, MABILAT, C

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Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase by Ehrt, S, Schnappinger, D, Bekiranov, S, Drenkow, J, Shi, S, Gingeras, T R, Gaasterland, T, Schoolnik, G, Nathan, C

“…Macrophage activation determines the outcome of infection by Mycobacterium tuberculosis (Mtb). Interferon-gamma (IFN-gamma) activates macrophages by driving…”
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Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation by Dong, S, Wang, E, Hsie, L, Cao, Y, Chen, X, Gingeras, T R

“…A method for identifying and validating single nucleotide polymorphisms (SNPs) with high-density oligonucleotide arrays without the need for locus-specific…”
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Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse by Bernstein, Bradley E., Kamal, Michael, Lindblad-Toh, Kerstin, Bekiranov, Stefan, Bailey, Dione K., Huebert, Dana J., McMahon, Scott, Karlsson, Elinor K., Kulbokas, Edward J., Gingeras, Thomas R., Schreiber, Stuart L., Lander, Eric S.

“…We mapped histone H3 lysine 4 di- and trimethylation and lysine 9/14 acetylation across the nonrepetitive portions of human chromosomes 21 and 22 and compared…”
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Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs by Cawley, Simon, Bekiranov, Stefan, Ng, Huck H, Kapranov, Philipp, Sekinger, Edward A, Kampa, Dione, Piccolboni, Antonio, Sementchenko, Victor, Cheng, Jill, Williams, Alan J, Wheeler, Raymond, Wong, Brant, Drenkow, Jorg, Yamanaka, Mark, Patel, Sandeep, Brubaker, Shane, Tammana, Hari, Helt, Gregg, Struhl, Kevin, Gingeras, Thomas R

“…Using high-density oligonucleotide arrays representing essentially all nonrepetitive sequences on human chromosomes 21 and 22, we map the binding sites in vivo…”
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Transcription-Based Amplification System and Detection of Amplified Human Immunodeficiency Virus Type 1 with a Bead-Based Sandwich Hybridization Format by Kwoh, D. Y., Davis, G. R., Whitfield, K. M., Chappelle, H. L., DiMichele, L. J., Gingeras, T. R.

“…The in vitro amplification of biologically important nucleic acids has proceeded principally by a strategy of DNA replication. Polymerase chain reaction was…”
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Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22 by Kampa, Dione, Cheng, Jill, Kapranov, Philipp, Yamanaka, Mark, Brubaker, Shane, Cawley, Simon, Drenkow, Jorg, Piccolboni, Antonio, Bekiranov, Stefan, Helt, Gregg, Tammana, Hari, Gingeras, Thomas R

“…In this report, we have achieved a richer view of the transcriptome for Chromosomes 21 and 22 by using high-density oligonucleotide arrays on cytosolic…”
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Self-sustained sequence replication (3SR): an isothermal transcription-based amplification system alternative to PCR by Fahy, E, Kwoh, D Y, Gingeras, T R

“…RNA transcription is a process employed by all cellular and viral systems to copy discrete segments of nucleotide sequences into multiple single stranded RNA…”
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High density synthetic oligonucleotide arrays by Lipshutz, R J, Fodor, S P, Gingeras, T R, Lockhart, D J

“…Experimental genomics involves taking advantage of sequence information to investigate and understand the workings of genes, cells and organisms. We have…”
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Large-Scale Transcriptional Activity in Chromosomes 21 and 22 by Kapranov, Philipp, Cawley, Simon E., Drenkow, Jorg, Bekiranov, Stefan, Strausberg, Robert L., Stephen P. A. Fodor, Gingeras, Thomas R.

“…The sequences of the human chromosomes 21 and 22 indicate that there are approximately 770 well-characterized and predicted genes. In this study, empirically…”
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Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells by GUATELLI, J. C, GINGERAS, T. R, RICHMAN, D. D

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Emergence of Dual Resistance to Zidovudine and Lamivudine in HIV-1-Infected Patients Treated With Zidovudine Plus Lamivudine as Initial Therapy by Kuritzkes, Daniel R, Shugarts, David, Bakhtiari, Minoo, Poticha, David, Johnson, Judy, Rubin, Marc, Gingeras, Thomas R, Kennedy, Mitchell, Eron, Joseph J

“…Presence of mutations associated with resistance to zidovudine or lamivudine was determined in isolates of HIV-1 obtained after long-term follow-up of 64…”
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Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris by ELLIS, S. B, BRUST, P. F, KOUTZ, P. J, WATERS, A. F, HARPOLD, M. M, GINGERAS, T. R

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MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis by Shi, Shuangping, Nathan, Carl, Schnappinger, Dirk, Drenkow, Jörg, Fuortes, Michele, Block, Ellen, Ding, Aihao, Gingeras, Thomas R, Schoolnik, Gary, Akira, Shizuo, Takeda, Kiyoshi, Ehrt, Sabine

“…Macrophages are activated from a resting state by a combination of cytokines and microbial products. Microbes are often sensed through Toll-like receptors…”
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Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication by Guatelli, J C, Whitfield, K M, Kwoh, D Y, Barringer, K J, Richman, D D, Gingeras, T R

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A Genome-Wide Survey of Sexually Dimorphic Expression of Drosophila miRNAs Identifies the Steroid Hormone-Induced miRNA let-7 as a Regulator of Sexual Identity by Fagegaltier, Delphine, König, Annekatrin, Gordon, Assaf, Lai, Eric C, Gingeras, Thomas R, Hannon, Gregory J, Shcherbata, Halyna R

“…G3: Genes|Genomes|Genetics has removed 10.1534/g3.114.012203 from early online publication. The early online version of the article was published in error and…”
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Nucleic acid amplification in vitro: detection of sequences with low copy numbers and application to diagnosis of human immunodeficiency virus type 1 infection by Guatelli, J C, Gingeras, T R, Richman, D D

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Nucleotide sequences from the adenovirus-2 genome by Gingeras, T R, Sciaky, D, Gelinas, R E, Bing-Dong, J, Yen, C E, Kelly, M M, Bullock, P A, Parsons, B L, O'Neill, K E, Roberts, R J

“…The sequence of 15,441 nucleotides from the adenovirus-2 genome has been determined and includes the regions between coordinates 0-32% and 89-100%. These…”
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Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays by Kozal, Michael J, Shah, Nila, Shen, Naiping, Yang, Robert, Fucini, Raymond, Merigan, Thomas C, Richman, Douglas D, Morris, Don, Hubbell, Earl, Chee, Mark, Gingeras, Thomas R

“…Naturally occurring mutations in HIV-1-infected patients have important implications for therapy and the outcome of clinical studies. However, little is known…”
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Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays by Gingeras, T R, Ghandour, G, Wang, E, Berno, A, Small, P M, Drobniewski, F, Alland, D, Desmond, E, Holodniy, M, Drenkow, J

“…High-density oligonucleotide arrays can be used to rapidly examine large amounts of DNA sequence in a high throughput manner. An array designed to determine…”
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