Search Results - "GIN, Alfred S"

Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent by Zhanel, George G., Cheung, Doris, Adam, Heather, Zelenitsky, Sheryl, Golden, Alyssa, Schweizer, Frank, Gorityala, Bala, Lagacé-Wiens, Philippe R. S., Walkty, Andrew, Gin, Alfred S., Hoban, Daryl J., Karlowsky, James A.

“…Eravacycline is an investigational, synthetic fluorocycline antibacterial agent that is structurally similar to tigecycline with two modifications to the…”
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Solithromycin: A Novel Fluoroketolide for the Treatment of Community-Acquired Bacterial Pneumonia by Zhanel, George G., Hartel, Erika, Adam, Heather, Zelenitsky, Sheryl, Zhanel, Michael A., Golden, Alyssa, Schweizer, Frank, Gorityala, Bala, Lagacé-Wiens, Philippe R. S., Walkty, Andrew J., Gin, Alfred S., Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Solithromycin is a novel fluoroketolide developed in both oral and intravenous formulations to address increasing macrolide resistance in pathogens causing…”
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Association between fluoroquinolone usage and a dramatic rise in ciprofloxacin-resistant Streptococcus pneumoniae in Canada, 1997–2006 by Adam, Heather J, Hoban, Daryl J, Gin, Alfred S, Zhanel, George G

“…Abstract This study evaluated the prevalence of fluoroquinolone usage and investigated the association between usage and resistance in respiratory isolates of…”
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Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations by Zhanel, George G., Lawrence, Courtney K., Adam, Heather, Schweizer, Frank, Zelenitsky, Sheryl, Zhanel, Michael, Lagacé-Wiens, Philippe R. S., Walkty, Andrew, Denisuik, Andrew, Golden, Alyssa, Gin, Alfred S., Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Relebactam (formerly known as MK-7655) is a non-β-lactam, bicyclic diazabicyclooctane, β-lactamase inhibitor that is structurally related to avibactam,…”
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Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination by Zhanel, George G., Lawson, Christopher D., Adam, Heather, Schweizer, Frank, Zelenitsky, Sheryl, Lagacé-Wiens, Philippe R. S., Denisuik, Andrew, Rubinstein, Ethan, Gin, Alfred S., Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Avibactam (formerly NXL104, AVE1330A) is a synthetic non-β-lactam, β-lactamase inhibitor that inhibits the activities of Ambler class A and C β-lactamases and…”
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Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination with Activity Against Multidrug-Resistant Gram-Negative Bacilli by Zhanel, George G., Chung, Phillip, Adam, Heather, Zelenitsky, Sheryl, Denisuik, Andrew, Schweizer, Frank, Lagacé-Wiens, Philippe R. S., Rubinstein, Ethan, Gin, Alfred S., Walkty, Andrew, Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Ceftolozane is a novel cephalosporin currently being developed with the β-lactamase inhibitor tazobactam for the treatment of complicated urinary tract…”
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Tedizolid: A Novel Oxazolidinone with Potent Activity Against Multidrug-Resistant Gram-Positive Pathogens by Zhanel, George G., Love, Riley, Adam, Heather, Golden, Alyssa, Zelenitsky, Sheryl, Schweizer, Frank, Gorityala, Bala, Lagacé-Wiens, Philippe R. S., Rubinstein, Ethan, Walkty, Andrew, Gin, Alfred S., Gilmour, Matthew, Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Tedizolid phosphate is a novel oxazolidinone prodrug (converted to the active form tedizolid by phosphatases in vivo) that has been developed and recently…”
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New Lipoglycopeptides: A Comparative Review of Dalbavancin, Oritavancin and Telavancin by Zhanel, George G., Calic, Divna, Schweizer, Frank, Zelenitsky, Sheryl, Adam, Heather, Lagacé-Wiens, Philippe R. S., Rubinstein, Ethan, Gin, Alfred S., Hoban, Daryl J., Karlowsky, James A.

“…Dalbavancin, oritavancin and telavancin are semisynthetic lipoglycopeptides that demonstrate promise for the treatment of patients with infections caused by…”
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Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin by Zhanel, George G, Lawson, Christopher D, Zelenitsky, Sheryl, Findlay, Brandon, Schweizer, Frank, Adam, Heather, Walkty, Andrew, Rubinstein, Ethan, Gin, Alfred S, Hoban, Daryl J, Lynch, Joseph P, Karlowsky, James A

“…Plazomicin (formerly ACHN-490) is a next-generation aminoglycoside that was synthetically derived from sisomicin by appending a hydroxy-aminobutyric acid…”
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Ceftaroline: A Novel Broad-Spectrum Cephalosporin with Activity against Meticillin-Resistant Staphylococcus aureus by Zhanel, George G., Sniezek, Grace, Schweizer, Frank, Zelenitsky, Sheryl, Lagacé-Wiens, Philippe R. S., Rubinstein, Ethan, Gin, Alfred S., Hoban, Daryl J., Karlowsky, James A.

“…Ceftaroline is a broad-spectrum cephalosporin currently under clinical investigation for the treatment of complicated skin and skin-structure infections…”
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Correction to: Imipenem–Relebactam and Meropenem–Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations by Zhanel, George G., Lawrence, Courtney K., Adam, Heather, Schweizer, Frank, Zelenitsky, Sheryl, Zhanel, Michael, Lagacé-Wiens, Philippe R. S., Walkty, Andrew, Denisuik, Andrew, Golden, Alyssa, Gin, Alfred S., Hoban, Daryl J., Lynch, Joseph P., Karlowsky, James A.

“…Section heading 5.2, which currently reads 5.2 Meropenem–Relebactam…”
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The new fluoroquinolones: A critical review by Zhanel, G G, Walkty, A, Vercaigne, L, Karlowsky, J A, Embil, J, Gin, A S, Hoban, D J

“…This paper reviews the literature available on the new fluoroquinolones - clinafloxacin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin…”
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Ceftobiprole: A Review of a Broad-Spectrum and Anti-MRSA Cephalosporin by Zhanel, George G., Lam, Ashley, Schweizer, Frank, Thomson, Kristjan, Walkty, Andrew, Rubinstein, Ethan, Gin, Alfred S., Hoban, Daryl J., Noreddin, Ayman M., Karlowsky, James A.

“…Ceftobiprole, an investigational cephalosporin, is currently in phase III clinical development. Ceftobiprole is a broad-spectrum cephalosporin with…”
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Comment: Clinical Pharmaceutics and Calcium–Ceftriaxone by Gin, Alfred S, Wheaton, Hannah, Dalton, Bruce

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Review of macrolides and ketolides: Focus on respiratory tract infections by ZHANEL, George G, DUECK, Maria, HOBAN, Daryl J, VERCAIGNE, Lavern M, EMBIL, John M, GIN, Alfred S, KARLOWSKY, James A

“…The first macrolide, erythromycin A, demonstrated broad-spectrum antimicrobial activity and was used primarily for respiratory and skin and soft tissue…”
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Clinical pharmaceutics and calcium-ceftriaxone by Gin, Alfred S, Wheaton, Hannah, Dalton, Bruce

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The ketolides: A critical review by ZHANEL, George G, WALTERS, Michael, NOREDDIN, Ayman, M.VERCAIGNE, Lavern, WIERZBOWSKI, Aleksandra, EMBIL, John M, GIN, Alfred S, DOUTHWAITE, Stephen, HOBAN, Daryl J

“…Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides…”
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A critical review of oxazolidinones: an alternative or replacement for glycopeptides and streptogramins? by Zhanel, G G, Shroeder, C, Vercaigne, L, Gin, A S, Embil, J, Hoban, D J

“…To review the available data on the oxazolidinones linezolid and eperezolid. Published reports were obtained by searching MEDLINE for articles published…”
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Dalbavancin and telavancin: novel lipoglycopeptides for the treatment of Gram-positive infections by Zhanel, George G, Trapp, Shannon, Gin, Alfred S, DeCorby, Mel, Lagacé-Wiens, Philippe R S, Rubinstein, Ethan, Hoban, Daryl J, Karlowsky, James A

“…Two glycopeptide analogues of vancomycin and teicoplanin have been developed with improved pharmacokinetic/pharmacodynamic parameters. Dalbavancin was derived…”
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A Review of New Fluoroquinolones : Focus on their Use in Respiratory Tract Infections by Zhanel, George G, Fontaine, Sonya, Adam, Heather, Schurek, Kristen, Mayer, Matt, Noreddin, Ayman M, Gin, Alfred S, Rubinstein, Ethan, Hoban, Daryl J

“…The new respiratory fluoroquinolones (gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and on the horizon, garenoxacin) offer many improved qualities…”
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