Search Results - "GILTIAY, N."

Direct regulation of IGF-binding protein 1 promoter by interleukin-1β via an insulin- and FoxO-1-independent mechanism by Shi, L, Banerjee, D, Dobierzewska, A, Sathishkumar, S, Karakashian, A A, Giltiay, N V, Nikolova-Karakashian, M N

“…The level of insulin-like growth factor-binding protein 1 (IGFBP1), a liver-produced serum protein that regulates insulin-like growth factor-I bioactivity,…”
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Lupus‐specific kidney deposits of HSP90 are associated with altered IgG idiotypic interactions of anti‐HSP90 autoantibodies by KENDEROV, A., MINKOVA, V., MIHAILOVA, D., GILTIAY, N., KYURKCHIEV, S., KEHAYOV, I., KAZATCHKINE, M., KAVERI, S., PASHOV, A.

“…SUMMARY Previous studies have shown that autoantibodies to heat shock protein 90 (HSP90) are elevated in a significant proportion of patients with systemic…”
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350 Toll-like receptor 7 signalling drives transitional b cells expansion and autoantibody production in systemic lupus erythematosus by Wang, T, Marken, J, Cerosaletti, K, Li, M, Elkon, K, Zeng, X, Giltiay, N

“…Background and aimsToll-like receptor 7 (TLR7) has been implicated in B cells activation and the generation of pathogenic autoantibodies. Newly-formed…”
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High Density Lipoprotein Binding to Scavenger Receptor, Class B, Type I Activates Endothelial Nitric-oxide Synthase in a Ceramide-dependent Manner by Li, Xiang-An, Titlow, William B., Jackson, Brian A., Giltiay, Nathalia, Nikolova-Karakashian, Mariana, Uittenbogaard, Annette, Smart, Eric J.

“…Recently it has been demonstrated that high density lipoprotein (HDL) binding to scavenger receptors, class B, type I (SR-BI) stimulates endothelial…”
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Astrocyte-Restricled Ablation of interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis by Kang, Z, Altuntas, C Z, Gulen, M F, Liu, C, Giltiay, N, Qin, H, Liu, L, Qian, W, Ransohoff, R M, Bergmann, C, Stohlman, S, Tuohy, V K, Li, X

“…Interleukin-17 (IL-17) secreted by T helper 17 (Th17) cells is essential in the development of experimental autoimmune encephalomyelitis (EAE). However, it…”
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Uptake and metabolism of low density lipoproteins with elevated ceramide content by human microvascular endothelial cells: implications for the regulation of apoptosis by Boyanovsky, Boris, Karakashian, Alexander, King, Kelley, Giltiay, Natalia, Nikolova-Karakashian, Mariana

“…Ceramide is a bioactive molecule involved in cellular responses to stress and inflammation. The major pathway for ceramide accumulation is via agonist-induced…”
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Lupus-specific kidney deposits of HSP90 are associated wtih altered IgG idiotypic interactions of anti-HSP90 autoantibodies by Kenderov, A, Minkova, V, Mihailova, D, Giltiay, N

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Autoantibodies to heat shock protein 90 in the human natural antibody repertoire by Pashov, Anastas, Kenderov, Andrey, Kyurkchiev, Stanimir, Kehayov, Ivan, Hristova, Svetla, Lacroix-Desmazes, Sebastien, Giltiay, Natalia, Varamballi, Sooryanarayana, Kazatchkine, Michael D, Kaveri, Srini V

“…The present study demonstrates the presence of natural autoantibodies of the IgG isotype directed against heat shock protein 90 (HSP90). The binding properties…”
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Expression of neutral sphingomyelinase‐2 (NSMase‐2) in primary rat hepatocytes modulates IL‐β‐induced JNK activation by Karakashian, Alexander A., Giltiay, Natalia V., Smith, George M., Nikolova-Karakashian, Mariana N.

“…ABSTRACT Neutral sphingomyelinase (NSMase) has been proposed to mediate interleukin (IL)‐1β signaling in liver. In this paper, we used adenovirus‐mediated gene…”
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Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis by Sathishkumar, Sabapathi, Boyanovski, Boris, Karakashian, Alexander, Rozenova, Krassimira A., Giltiay, Natalia V., Kudrimoti, Mahesh, Mohiuddin, Mohammed, Ahmed, Mansoor M., Nikolova-Karakashian, Mariana

“…Spatially Fractionated high dose (Grid) Radiation Treatment (SFGRT) involves irradiation of bulky tumors with one high, grid-delivered, dose of 15 Gy followed…”
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Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1β in hepatocytes by Giltiay, Natalia V., Karakashian, Alexander A., Alimov, Alexander P., Ligthle, Sandy, Nikolova-Karakashian, Mariana N.

“…Interleukin-1β (IL-1β) is a major inducer of liver acute-phase protein expression in response to infection. Several transcription factors, including…”
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