Search Results - "GILARDI, Federica"

Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes by Porcu, Eleonora, Gilardi, Federica, Darrous, Liza, Yengo, Loic, Bararpour, Nasim, Gasser, Marie, Marques-Vidal, Pedro, Froguel, Philippe, Waeber, Gerard, Thomas, Aurelien, Kutalik, Zoltán

“…The number of people affected by Type 2 diabetes mellitus (T2DM) is close to half a billion and is on a sharp rise, representing a major and growing public…”
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DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies by Bararpour, Nasim, Gilardi, Federica, Carmeli, Cristian, Sidibe, Jonathan, Ivanisevic, Julijana, Caputo, Tiziana, Augsburger, Marc, Grabherr, Silke, Desvergne, Béatrice, Guex, Nicolas, Bochud, Murielle, Thomas, Aurelien

“…As a powerful phenotyping technology, metabolomics provides new opportunities in biomarker discovery through metabolome-wide association studies (MWAS) and the…”
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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue by GALMOZZI, Andrea, MITRO, Nico, VALENTE, Sergio, GUERRINI, Uliano, CARUSO, Donatella, MAI, Antonello, SAEZ, Enrique, DE FABIANI, Emma, CRESTANI, Maurizio, FERRARI, Alessandra, GERS, Elise, GILARDI, Federica, GODIO, Cristina, CERMENATI, Gaia, GUALERZI, Alice, DONETTI, Elena, ROTILI, Dante

“…Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders…”
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HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning by Ferrari, Alessandra, Longo, Raffaella, Fiorino, Erika, Silva, Rui, Mitro, Nico, Cermenati, Gaia, Gilardi, Federica, Desvergne, Béatrice, Andolfo, Annapaola, Magagnotti, Cinzia, Caruso, Donatella, Fabiani, Emma De, Hiebert, Scott W., Crestani, Maurizio

“…White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational…”
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Transcriptional regulatory logic of the diurnal cycle in the mouse liver by Sobel, Jonathan Aryeh, Krier, Irina, Andersin, Teemu, Raghav, Sunil, Canella, Donatella, Gilardi, Federica, Kalantzi, Alexandra Styliani, Rey, Guillaume, Weger, Benjamin, Gachon, Frédéric, Dal Peraro, Matteo, Hernandez, Nouria, Schibler, Ueli, Deplancke, Bart, Naef, Felix

“…Many organisms exhibit temporal rhythms in gene expression that propel diurnal cycles in physiology. In the liver of mammals, these rhythms are controlled by…”
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Will Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations? by Gilardi, Federica, Augsburger, Marc, Thomas, Aurelien

“…A growing number of evidence demonstrates that ancestral exposure to xenobiotics (pollutants, drugs of abuse, etc.) can perturb the physiology and behavior of…”
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Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue by Caputo, Tiziana, Tran, Van Du T., Bararpour, Nasim, Winkler, Carine, Aguileta, Gabriela, Trang, Khanh Bao, Giordano Attianese, Greta M. P., Wilson, Anne, Thomas, Aurelien, Pagni, Marco, Guex, Nicolas, Desvergne, Béatrice, Gilardi, Federica

“…Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-associated…”
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Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles by Le Martelot, Gwendal, Canella, Donatella, Symul, Laura, Migliavacca, Eugenia, Gilardi, Federica, Liechti, Robin, Martin, Olivier, Harshman, Keith, Delorenzi, Mauro, Desvergne, Béatrice, Herr, Winship, Deplancke, Bart, Schibler, Ueli, Rougemont, Jacques, Guex, Nicolas, Hernandez, Nouria, Naef, Felix

“…Interactions of cell-autonomous circadian oscillators with diurnal cycles govern the temporal compartmentalization of cell physiology in mammals. To understand…”
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Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system by Toffoli, Barbara, Gilardi, Federica, Winkler, Carine, Soderberg, Magnus, Kowalczuk, Laura, Arsenijevic, Yvan, Bamberg, Krister, Bonny, Olivier, Desvergne, Béatrice

“…Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcription factor involved in many aspects of metabolism, immune response, and…”
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PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration by Dammone, Gabriele, Karaz, Sonia, Lukjanenko, Laura, Winkler, Carine, Sizzano, Federico, Jacot, Guillaume, Migliavacca, Eugenia, Palini, Alessio, Desvergne, Béatrice, Gilardi, Federica, Feige, Jerome N

“…Skeletal muscle is a regenerative tissue which can repair damaged myofibers through the activation of tissue-resident muscle stem cells (MuSCs). Many muscle…”
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Randomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods by Joye, Timothée, Déglon, Julien, Donzé, Nicolas, Gilardi, Federica, Sidibé, Jonathan, Favrat, Bernard, Augsburger, Marc, Thomas, Aurélien

“…According to the World Health Organization, road traffic injuries lead to 1.3 million deaths each year and represent the leading cause of death for young…”
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Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg -Null Mice by Schiffrin, Mariano, Winkler, Carine, Quignodon, Laure, Naldi, Aurélien, Trötzmüller, Martin, Köfeler, Harald, Henry, Hugues, Parini, Paolo, Desvergne, Béatrice, Gilardi, Federica

“…Men with nonalcoholic fatty liver disease (NAFLD) are more exposed to nonalcoholic steatohepatitis (NASH) and liver fibrosis than women. However, the…”
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Hemicentin 1 influences podocyte dynamic changes in glomerular diseases by Toffoli, Barbara, Zennaro, Cristina, Winkler, Carine, Giordano Attianese, Greta Maria Paola, Bernardi, Stella, Carraro, Michele, Gilardi, Federica, Desvergne, Béatrice

“…Different complex mechanisms control the morphology of podocyte foot processes and their interactions with the underlying basement membrane. Injuries to this…”
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Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice by Wilson, Anne, Fu, He, Schiffrin, Mariano, Winkler, Carine, Koufany, Meriem, Jouzeau, Jean-Yves, Bonnet, Nicolas, Gilardi, Federica, Renevey, François, Luther, Sanjiv A, Moulin, David, Desvergne, Béatrice

“…Adult hematopoiesis takes place in the perivascular zone of the bone cavity, where endothelial cells, mesenchymal stromal/stem cells and their derivatives such…”
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Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals by Gilardi, Federica, Migliavacca, Eugenia, Naldi, Aurélien, Baruchet, Michaël, Canella, Donatella, Le Martelot, Gwendal, Guex, Nicolas, Desvergne, Béatrice

“…In mammals, the circadian clock allows them to anticipate and adapt physiology around the 24 hours. Conversely, metabolism and food consumption regulate the…”
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Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Caruso, Donatella, Galli, Giovanni, Crestani, Maurizio

“…Bile acid metabolism plays an essential role in cholesterol homeostasis and is critical for the initiation of atherosclerotic disease. However, despite the…”
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A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver by Canella, Donatella, Bernasconi, David, Gilardi, Federica, LeMartelot, Gwendal, Migliavacca, Eugenia, Praz, Viviane, Cousin, Pascal, Delorenzi, Mauro, Hernandez, Nouria

“…The genomic loci occupied by RNA polymerase (RNAP) III have been characterized in human culture cells by genome-wide chromatin immunoprecipitations, followed…”
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Lack of Adiponectin Drives Hyperosteoclastogenesis in Lipoatrophic Mice by Madel, Maria-Bernadette, Fu, He, Pierroz, Dominique D, Schiffrin, Mariano, Winkler, Carine, Wilson, Anne, Pochon, Cécile, Toffoli, Barbara, Taïeb, Mahdia, Jouzeau, Jean-Yves, Gilardi, Federica, Ferrari, Serge, Bonnet, Nicolas, Blin-Wakkach, Claudine, Desvergne, Béatrice, Moulin, David

“…Long bones from mammals host blood cell formation and contain multiple cell types, including adipocytes. Physiological functions of bone marrow adipocytes are…”
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Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production by Corsini, Emanuela, Viviani, Barbara, Birindelli, Sarah, Gilardi, Federica, Torri, Anna, Codecà, Ilaria, Lucchi, Laura, Bartesaghi, Stefano, Galli, Corrado L., Marinovich, Marina, Colosio, Claudio

“…Mancozeb, a polymeric complex of manganese ethylenebisdithiocarbamate with zinc salt, is widely used in agriculture as fungicide. Literature data indicate that…”
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When food meets man: the contribution of epigenetics to health by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Galmozzi, Andrea, Caruso, Donatella, Crestani, Maurizio

“…Post-translational modifications of chromatin contribute to the epigenetic control of gene transcription. The response to food intake and individual nutrients…”
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