Search Results - "GIEBISCH, Gerhard"

KCNJ10 determines the expression of the apical Na-Cl cotransporter (NCC) in the early distal convoluted tubule (DCT1) by Zhang, Chengbiao, Wang, Lijun, Zhang, Junhui, Su, Xiao-Tong, Lin, Dao-Hong, Scholl, Ute I., Giebisch, Gerhard, Lifton, Richard P., Wang, Wen-Hui

“…The renal phenotype induced by loss-of-function mutations of inwardly rectifying potassium channel (Kir), Kcnj10 (Kir4.1), includes salt wasting,…”
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Regulation of potassium (K) handling in the renal collecting duct by Wang, Wen-Hui, Giebisch, Gerhard

“…This review provides an overview of the molecular mechanisms of K transport in the mammalian connecting tubule (CNT) and cortical collecting duct (CCD), both…”
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Renal potassium transport: mechanisms and regulation by Giebisch, G

“…The regulation of potassium metabolism involves mechanisms for the appropriate distribution between the intra- and extracellular fluid compartments and for the…”
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A long affair with renal tubules by Giebisch, Gerhard H

“…This essay provides a summary of my professional activities. My interest in renal physiology started as a medical student in Vienna, when I became acquainted…”
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Molecular Diversity and Regulation of Renal Potassium Channels by Hebert, Steven C, Desir, Gary, Giebisch, Gerhard, Wang, Wenhui

“…Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, and Department of Medicine, Yale University and VA CT Medical…”
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Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK) by Lin, Dao-Hong, Yue, Peng, Yarborough, Orlando, Scholl, Ute I., Giebisch, Gerhard, Lifton, Richard P., Rinehart, Jesse, Wang, Wen-Hui

“…With-no-lysine kinase 4 (WNK4) inhibits the activity of the potassium channel KCNJ1 (ROMK) in the distal nephron, thereby contributing to the maintenance of…”
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Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins by Wagner, Carsten A, Loffing-Cueni, Dominique, Yan, Qingshang, Schulz, Nicole, Fakitsas, Panagiotis, Carrel, Monique, Wang, Tong, Verrey, Francois, Geibel, John P, Giebisch, Gerhard, Hebert, Steven C, Loffing, Johannes

“…Bartter's syndrome represents a group of hereditary salt- and water-losing renal tubulopathies caused by loss-of-function mutations in proteins mediating or…”
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WNK4 regulates the balance between renal NaCl reabsorption and K + secretion by O'Connell, Anthony D, MacGregor, Gordon G, Wilson, Frederick H, Dong, Ke, Kahle, Kristopher T, Lalioti, Maria D, Lifton, Richard P, Leng, Qiang, Hebert, Steven C, Giebisch, Gerhard, Rapson, Alicia K

“…A key question in systems biology is how diverse physiologic processes are integrated to produce global homeostasis. Genetic analysis can contribute by…”
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Potassium Channelopathies and Gastrointestinal Ulceration by Han, Jaeyong, Lee, Seung Hun, Giebisch, Gerhard, Wang, Tong

“…Potassium channels and transporters maintain potassium homeostasis and play significant roles in several different biological actions via potassium ion…”
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Steven C. Hebert: a personal dedication by Giebisch, Gerhard H.

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Renal Potassium Homeostasis: A Short Historical Perspective by Giebisch, Gerhard H., MD, Wingo, Charles S., MD

“…Summary During the past century, investigators have increased our understanding of renal potassium excretion significantly using many techniques. Notable among…”
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Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status by Wagner, Carsten A., Finberg, Karin E., Stehberger, Paul A., Lifton, Richard P., Giebisch, Gerhard H., Aronson, Peter S., Geibel, John P.

“…Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status. Pendrin belongs to a superfamily of Cl-/anion exchangers…”
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Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct by Lu, Ming, Dong, Ke, Egan, Marie E, Giebisch, Gerhard H, Boulpaep, Emile L, Hebert, Steven C

“…The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in many segments of the mammalian nephron, where it may interact with and modulate…”
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Paracellular Cl- Permeability Is Regulated by WNK4 Kinase: Insight into Normal Physiology and Hypertension by Kahle, Kristopher T., MacGregor, Gordon G., Wilson, Frederick H., Van Hoek, Alfred N., Brown, Dennis, Ardito, Thomas, Kashgarian, Michael, Giebisch, Gerhard, Hebert, Steven C., Boulpaep, Emile L., Lifton, Richard P.

“…Paracellular ion flux across epithelia occurs through selective and regulated pores in tight junctions; this process is poorly understood. Mutations in the…”
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Inhibition of MAPK stimulates the Ca²⁺-dependent big-conductance K channels in cortical collecting duct by Li, Dimin, Wang, Zhijian, Sun, Peng, Jin, Yan, Lin, Dao-Hong, Hebert, Steven C, Giebisch, Gerhard, Wang, Wen-Hui

“…The kidney plays a key role in maintaining potassium (K) homeostasis. K excretion is determined by the balance between K secretion and absorption in distal…”
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The B1-Subunit of the H+ATPase Is Required for Maximal Urinary Acidification by Finberg, Karin E., Wagner, Carsten A., Bailey, Matthew A., Păunescu, Teodor G., Breton, Sylvie, Brown, Dennis, Giebisch, Gerhard, Geibel, John P., Lifton, Richard P.

“…The multisubunit vacuolar-type H+ATPases mediate acidification of various intracellular organelles and in some tissues mediate H+secretion across the plasma…”
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Determination of the Self-ignition Behaviour of Bulk Materials from Heat Storage Tests below Atmospheric Pressure by Simon Seitz, Jürgen Franke, Gerhard Giebisch

“…Is a displacement of the self-ignition temperature up to higher temperatures possible by a pressure reduction? Therefore, the influence of an air pressure…”
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A trail of research on potassium by Giebisch, Gerhard H.

“…A complex pump-leak system involving both active and passive transport mechanisms is responsible for the appropriate distribution of potassium (K) between the…”
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Identification of a Chloride-Formate Exchanger Expressed on the Brush Border Membrane of Renal Proximal Tubule Cells by Knauf, Felix, Yang, Chao-Ling, Thomson, R. Brent, Mentone, Sue Ann, Giebisch, Gerhard, Aronson, Peter S.

“…A key function of the proximal tubule is retrieval of most of the vast quantities of NaCl and water filtered by the kidney. Physiological studies using brush…”
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Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity by Cantone, Alessandra, Yang, Xinbo, Yan, Qingshang, Giebisch, Gerhard, Hebert, Steven C, Wang, Tong

“…ROMK-deficient (Romk(-/-)) mice exhibit polyuria, natriuresis, and kaliuresis similar to individuals with type II Bartter's form of hyperprostaglandin E…”
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