Search Results - "GIAVEDONI, Luis"

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response by Jacquelin, Béatrice, Mayau, Véronique, Targat, Brice, Liovat, Anne-Sophie, Kunkel, Désirée, Petitjean, Gaël, Dillies, Marie-Agnès, Roques, Pierre, Butor, Cécile, Silvestri, Guido, Giavedoni, Luis D, Lebon, Pierre, Barré-Sinoussi, Françoise, Benecke, Arndt, Müller-Trutwin, Michaela C

“…African green monkeys (AGMs) infected with the AGM type of SIV (SIVagm) do not develop chronic immune activation and AIDS, despite viral loads similar to those…”
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A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates by Callendret, Benoit, Vellinga, Jort, Wunderlich, Kerstin, Rodriguez, Ariane, Steigerwald, Robin, Dirmeier, Ulrike, Cheminay, Cedric, Volkmann, Ariane, Brasel, Trevor, Carrion, Ricardo, Giavedoni, Luis D, Patterson, Jean L, Mire, Chad E, Geisbert, Thomas W, Hooper, Jay W, Weijtens, Mo, Hartkoorn-Pasma, Jutta, Custers, Jerome, Grazia Pau, Maria, Schuitemaker, Hanneke, Zahn, Roland

“…The search for a universal filovirus vaccine that provides protection against multiple filovirus species has been prompted by sporadic but highly lethal…”
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GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees by Lanford, Robert E, Guerra, Bernadette, Chavez, Deborah, Giavedoni, Luis, Hodara, Vida L, Brasky, Kathleen M, Fosdick, Abigail, Frey, Christian R, Zheng, Jim, Wolfgang, Grushenka, Halcomb, Randall L, Tumas, Daniel B

“…Background & Aims Direct-acting antiviral agents suppress hepatitis B virus (HBV) load, but they require life-long use. Stimulation of the innate immune system…”
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Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus by Pantoja, Petraleigh, Pérez-Guzmán, Erick X., Rodríguez, Idia V., White, Laura J., González, Olga, Serrano, Crisanta, Giavedoni, Luis, Hodara, Vida, Cruz, Lorna, Arana, Teresa, Martínez, Melween I., Hassert, Mariah A., Brien, James D., Pinto, Amelia K., de Silva, Aravinda, Sariol, Carlos A.

“…Zika virus (ZIKV) is a re-emerging virus that has recently spread into dengue virus (DENV) endemic regions and cross-reactive antibodies (Abs) could…”
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Experimental Zika Virus Inoculation in a New World Monkey Model Reproduces Key Features of the Human Infection by Chiu, Charles Y., Sánchez-San Martín, Claudia, Bouquet, Jerome, Li, Tony, Yagi, Shigeo, Tamhankar, Manasi, Hodara, Vida L., Parodi, Laura M., Somasekar, Sneha, Yu, Guixia, Giavedoni, Luis D., Tardif, Suzette, Patterson, Jean

“…A monkey model of Zika virus (ZIKV) infection is urgently needed to better understand transmission and pathogenesis, given its proven association with fetal…”
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Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling by Reyes, Luis F, Restrepo, Marcos I, Hinojosa, Cecilia A, Soni, Nilam J, Anzueto, Antonio, Babu, Bettina L, Gonzalez-Juarbe, Norberto, Rodriguez, Alejandro H, Jimenez, Alejandro, Chalmers, James D, Aliberti, Stefano, Sibila, Oriol, Winter, Vicki T, Coalson, Jacqueline J, Giavedoni, Luis D, Dela Cruz, Charles S, Waterer, Grant W, Witzenrath, Martin, Suttorp, Norbert, Dube, Peter H, Orihuela, Carlos J

“…Up to one-third of patients hospitalized with pneumococcal pneumonia experience major adverse cardiac events (MACE) during or after pneumonia. In mice,…”
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Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection by Fraietta, Joseph A, Mueller, Yvonne M, Yang, Guibin, Boesteanu, Alina C, Gracias, Donald T, Do, Duc H, Hope, Jennifer L, Kathuria, Noshin, McGettigan, Shannon E, Lewis, Mark G, Giavedoni, Luis D, Jacobson, Jeffrey M, Katsikis, Peter D

“…The role of Type I interferon (IFN) during pathogenic HIV and SIV infections remains unclear, with conflicting observations suggesting protective versus…”
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Urinary cytokine measurements do not reflect surgery‐induced inflammation in rhesus macaques by Higham, James P., Cooper, Eve B., Whalen, Connor, Stahl‐Hennig, Christiane, Giavedoni, Luis D., Heistermann, Michael

“…Measurement of the health and disease status of free‐ranging primates is often limited by a lack of available biomarkers of immune activation and inflammation…”
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A Non-Human Primate Model of Severe Pneumococcal Pneumonia by Reyes, Luis F, Restrepo, Marcos I, Hinojosa, Cecilia A, Soni, Nilam J, Shenoy, Anukul T, Gilley, Ryan P, Gonzalez-Juarbe, Norberto, Noda, Julio R, Winter, Vicki T, de la Garza, Melissa A, Shade, Robert E, Coalson, Jacqueline J, Giavedoni, Luis D, Anzueto, Antonio, Orihuela, Carlos J

“…Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and infectious death in adults worldwide. A non-human primate model is needed to…”
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Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets by Singh, Dhiraj Kumar, Singh, Bindu, Ganatra, Shashank R., Gazi, Michal, Cole, Journey, Thippeshappa, Rajesh, Alfson, Kendra J., Clemmons, Elizabeth, Gonzalez, Olga, Escobedo, Ruby, Lee, Tae-Hyung, Chatterjee, Ayan, Goez-Gazi, Yenny, Sharan, Riti, Gough, Maya, Alvarez, Cynthia, Blakley, Alyssa, Ferdin, Justin, Bartley, Carmen, Staples, Hilary, Parodi, Laura, Callery, Jessica, Mannino, Amanda, Klaffke, Benjamin, Escareno, Priscilla, Platt, Roy N., Hodara, Vida, Scordo, Julia, Gautam, Shalini, Vilanova, Andreu G., Olmo-Fontanez, Angelica, Schami, Alyssa, Oyejide, Adelekan, Ajithdoss, Dharani K., Copin, Richard, Baum, Alina, Kyratsous, Christos, Alvarez, Xavier, Ahmed, Mushtaq, Rosa, Bruce, Goodroe, Anna, Dutton, John, Hall-Ursone, Shannan, Frost, Patrice A., Voges, Andra K., Ross, Corinna N., Sayers, Ken, Chen, Christopher, Hallam, Cory, Khader, Shabaana A., Mitreva, Makedonka, Anderson, Timothy J. C., Martinez-Sobrido, Luis, Patterson, Jean L., Turner, Joanne, Torrelles, Jordi B., Dick, Edward J., Brasky, Kathleen, Schlesinger, Larry S., Giavedoni, Luis D., Carrion, Ricardo, Kaushal, Deepak

“…Non-human primate models will expedite therapeutics and vaccines for coronavirus disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe…”
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Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus) by Manickam, Cordelia, Wachtman, Lynn, Martinot, Amanda J, Giavedoni, Luis D, Reeves, R Keith

“…Chronic hepatitis C has been associated with metabolic syndrome that includes insulin resistance, hepatic steatosis and obesity. These metabolic aberrations…”
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Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections by Greenwood, Edward J D, Schmidt, Fabian, Kondova, Ivanela, Niphuis, Henk, Hodara, Vida L, Clissold, Leah, McLay, Kirsten, Guerra, Bernadette, Redrobe, Sharon, Giavedoni, Luis D, Lanford, Robert E, Murthy, Krishna K, Rouet, François, Heeney, Jonathan L

“…The virus-host relationship in simian immunodeficiency virus (SIV) infected chimpanzees is thought to be different from that found in other SIV infected…”
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Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity by Obregon-Perko, Veronica, Mannino, Amanda, Ladner, Jason T, Hodara, Vida, Ebrahimi, Diako, Parodi, Laura, Callery, Jessica, Palacios, Gustavo, Giavedoni, Luis D

“…While simian immunodeficiency virus (SIV) infection is non-pathogenic in naturally infected African nonhuman primate hosts, experimental or accidental…”
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A marmoset model for Mycobacterium avium complex pulmonary disease by Peters, Jay, Maselli, Diego Jose, Mangat, Mandeep, Coalson, Jacqueline J, Hinojosa, Cecilia, Giavedoni, Luis, Brown-Elliott, Barbara A, Chan, Edward, Griffith, David

“…Mycobacterium avium complex, is the most common nontuberculous mycobacterial respiratory pathogen in humans. Disease mechanisms are poorly understood due to…”
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Multiplexed Simian Immunodeficiency Virus-Specific Paired RNA-Guided Cas9 Nickases Inactivate Proviral DNA by Smith, Lisa M, Ladner, Jason T, Hodara, Vida L, Parodi, Laura M, Harris, R Alan, Callery, Jessica E, Lai, Zhao, Zou, Yi, Raveedran, Muthuswamy, Rogers, Jeffrey, Giavedoni, Luis D

“…Human and simian immunodeficiency virus (HIV and SIV) infections establish lifelong reservoirs of cells harboring an integrated proviral genome. Genome editing…”
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Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology by Giavedoni, Luis D.

“…Cytokines and chemokines are soluble mediators of the immune system that play a crucial role in intercellular signaling, and in the recruitment of cells to…”
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Time elapsed between Zika and dengue virus infections affects antibody and T cell responses by Pérez-Guzmán, Erick X., Pantoja, Petraleigh, Serrano-Collazo, Crisanta, Hassert, Mariah A., Ortiz-Rosa, Alexandra, Rodríguez, Idia V., Giavedoni, Luis, Hodara, Vida, Parodi, Laura, Cruz, Lorna, Arana, Teresa, White, Laura J., Martínez, Melween I., Weiskopf, Daniela, Brien, James D., de Silva, Aravinda, Pinto, Amelia K., Sariol, Carlos A.

“…Zika virus (ZIKV) and dengue virus (DENV) are co-endemic in many parts of the world, but the impact of ZIKV infection on subsequent DENV infection is not well…”
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Comparative Characterization of Transfection- and Infection-Derived Simian Immunodeficiency Virus Challenge Stocks for In Vivo Nonhuman Primate Studies by Del Prete, Gregory Q, Scarlotta, Matthew, Newman, Laura, Reid, Carolyn, Parodi, Laura M, Roser, James D, Oswald, Kelli, Marx, Preston A, Miller, Christopher J, Desrosiers, Ronald C, Barouch, Dan H, Pal, Ranajit, Piatak, Jr, Michael, Chertova, Elena, Giavedoni, Luis D, O'Connor, David H, Lifson, Jeffrey D, Keele, Brandon F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection by Hao, Xing Pei, Lucero, Carissa M., Turkbey, Baris, Bernardo, Marcelino L., Morcock, David R., Deleage, Claire, Trubey, Charles M., Smedley, Jeremy, Klatt, Nichole R., Giavedoni, Luis D., Kristoff, Jan, Xu, Amy, Del Prete, Gregory Q., Keele, Brandon F., Rao, Srinivas S., Alvord, W. Gregory, Choyke, Peter L., Lifson, Jeffrey D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona, Estes, Jacob D.

“…Mucosal damage to the gastrointestinal (GI) tract with resulting microbial translocation is hypothesized to significantly contribute to the heightened and…”
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Baboon CD8 T cells suppress SIVmac infection in CD4 T cells through contact-dependent production of MIP-1α, MIP-1β, and RANTES by Obregon-Perko, Veronica, Hodara, Vida L., Parodi, Laura M., Giavedoni, Luis D.

“…•PBMC and CD4 cells from naïve rhesus macaques are equally permissive to SIVmac.•SIVmac is restricted in PBMC but not in isolated CD4 cells from naïve…”
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