Search Results - "GIAVARESI, G"
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Deregulated miRNAs in bone health: Epigenetic roles in osteoporosis
Published in Bone (New York, N.Y.) (01-05-2019)“…MicroRNA (miRNA) has shown to enhance or inhibit cell proliferation, differentiation and activity of different cell types in bone tissue. The discovery of…”
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Deregulated miRNAs in osteoporosis: effects in bone metastasis
Published in Cellular and molecular life sciences : CMLS (01-10-2019)“…Starting from their role exerted on osteoblast and osteoclast differentiation and activity pathways, microRNAs (miRNAs) have been recently identified as…”
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Unlocking diagnosis of sarcopenia: The role of circulating biomarkers – A clinical systematic review
Published in Mechanisms of ageing and development (01-12-2024)“…Sarcopenia, the gradual loss of muscle mass, strength, and function with age, poses a significant risk to older adults, making early diagnosis crucial for…”
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Gene therapy for chondral and osteochondral regeneration: is the future now?
Published in Cellular and molecular life sciences : CMLS (01-02-2018)“…Gene therapy might represent a promising strategy for chondral and osteochondral defects repair by balancing the management of temporary joint mechanical…”
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Histological, Histomorphometrical, and Biomechanical Studies of Bone-Implanted Medical Devices: Hard Resin Embedding
Published in BioMed research international (2020)“…The growing incidence of degenerative musculoskeletal disorders as well as lifestyle changes has led to an increase in the surgical procedures involving…”
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Role of bone marrow adipocytes in bone metastasis development and progression: a systematic review
Published in Frontiers in endocrinology (Lausanne) (29-08-2023)“…Bone marrow adipocytes (BMAs) are the most plentiful cells in the bone marrow and function as an endocrine organ by producing fatty acids, cytokines, and…”
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Engineered exosomes: A new promise for the management of musculoskeletal diseases
Published in Biochimica et biophysica acta. General subjects (01-09-2018)“…Exosomes are nanovesicles actively secreted by potentially all cell types, including tumour cells, with the primary role of extracellular systemic…”
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The role of subscapularis repair following reverse shoulder arthroplasty: systematic review and meta-analysis
Published in Archives of orthopaedic and trauma surgery (01-09-2022)“…Purpose Inadequate subscapularis repair has been advocated as one of the contributing factors for dislocation in reverse total shoulder arthroplasty;…”
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Current Trends in the Evaluation of Osteochondral Lesion Treatments: Histology, Histomorphometry, and Biomechanics in Preclinical Models
Published in BioMed research international (2019)“…Osteochondral lesions (OCs) are typically of traumatic origins but are also caused by degenerative conditions, in primis osteoarthritis (OA). On the other…”
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10
The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel
Published in Biomaterials (01-06-2005)“…In vitro and in vivo behaviour of an injectable silk fibroin (SF) hydrogel was studied through osteoblast cultures and after implantation in critical-size…”
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Bone regeneration in a rabbit critical femoral defect by means of magnetic hydroxyapatite macroporous scaffolds
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-02-2018)“…Magnetic scaffolds have recently attracted significant attention in tissue engineering due to the prospect of improving bone tissue formation by conveying…”
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Efficacy of using autologous cells with graft substitutes for spinal fusion surgery: A systematic review and meta‐analysis of clinical outcomes and imaging features
Published in JOR-spine (01-09-2024)“…Over the past several decades, there has been a notable increase in the total number of spinal fusion procedures worldwide. Advanced spinal fusion techniques,…”
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A Rationale for the Use of Clotted Vertebral Bone Marrow to Aid Tissue Regeneration Following Spinal Surgery
Published in Scientific reports (05-03-2020)“…Vertebral body bone marrow aspirate (V-BMA), easily accessible simultaneously with the preparation of the site for pedicle screw insertion during spinal…”
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Innovative magnetic scaffolds for orthopedic tissue engineering
Published in Journal of biomedical materials research. Part A (01-09-2012)“…The use of magnetism in tissue engineering is a very promising approach, in fact magnetic scaffolds are able not only to support tissue regeneration, but they…”
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In vivo effect of two different pulsed electromagnetic field frequencies on osteoarthritis
Published in Journal of orthopaedic research (01-05-2014)“…ABSTRACT Osteoarthritis (OA) is a joint pathology characterized by fibrillation, reduced cartilage thickness and subchondral bone sclerosis. There is evidence…”
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Modifying bone scaffold architecture in vivo with permanent magnets to facilitate fixation of magnetic scaffolds
Published in Bone (New York, N.Y.) (01-10-2013)“…Abstract The fundamental elements of tissue regeneration are cells, biochemical signals and the three-dimensional microenvironment. In the described approach,…”
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Chondroprotective activity of n-acetyl phenylalanine glucosamine derivative on knee joint structure and inflammation in a murine model of osteoarthritis
Published in Osteoarthritis and cartilage (01-04-2017)“…Summary Objective Osteoarthritis (OA), the most common chronic degenerative joint disease, is characterized by joint structure changes and inflammation, both…”
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Long-term in vivo experimental investigations on magnesium doped hydroxyapatite bone substitutes
Published in Journal of materials science. Materials in medicine (01-06-2014)“…Despite several efforts to find suitable alternatives to autologous bone, no bone substitute currently available provides the same characteristics and…”
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In vivo study on the healing of bone defects treated with bone marrow stromal cells, platelet-rich plasma, and freeze-dried bone allografts, alone and in combination
Published in Journal of orthopaedic research (01-05-2006)“…The repair of confined trabecular bone defects in rabbits treated by autologous bone marrow stromal cells (BMSC), platelet‐rich plasma (PRP), freeze‐dried bone…”
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Subchondral bone response to injected adipose-derived stromal cells for treating osteoarthritis using an experimental rabbit model
Published in Biotechnic & histochemistry (03-04-2017)“…Although articular cartilage is the target of osteoarthritis (OA), its deterioration is not always clearly associated with patient symptoms. Because a…”
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