Search Results - "GIANNAKOUROS, T"

Distribution of SRPK1 in human brain by Mytilinaios, D.G., Tsamis, K.I., Nikolakaki, E., Giannakouros, T.

“…► SRPK1 is expressed in human brain in neuron-specific manner and not in glia. ► SRPK1 is expressed in human brain in a region-specific manner. ► SRPK1 is…”
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SR Protein Kinase 1 Inhibition by TAF15 by Koukiali, Anastasia, Daniilidou, Makrina, Mylonis, Ilias, Giannakouros, Thomas, Nikolakaki, Eleni

“…Although SRPKs were discovered nearly 30 years ago, our understanding of their mode of regulation is still limited. Regarded as constitutively active enzymes…”
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Post-translational processing of Schizosaccharomyces pombe YPT proteins by NEWMAN, C. M. H, GIANNAKOUROS, T, HANCOCK, J. F, FAWELL, E. H, ARMSTRONG, J, MAGEE, A. I

“…ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl,…”
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Lipid modifications and function of the ras superfamily of proteins by Magee, A I, Newman, C M, Giannakouros, T, Hancock, J F, Fawell, E, Armstrong, J

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Post-translational processing of Schizosaccharomyces pombe YPT5 protein. In vitro and in vivo analysis of processing mutants by Giannakouros, T, Newman, C.M.H, Craighead, M.W, Armstrong, J, Magee, A.I

“…SpYPT5p is a member of the rab/YPT small GTP-binding protein family, which is believed to be involved in the regulation of intracellular trafficking. The…”
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Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1 by Polioudaki, Hara, Kourmouli, Niki, Drosou, Victoria, Bakou, Alexandra, Theodoropoulos, Panayiotis A, Singh, Prim B, Giannakouros, Thomas, Georgatos, Spyros D

“…We have recently shown that heterochromatin protein 1 (HP1) interacts with the nuclear envelope in an acetylation‐dependent manner. Using purified components…”
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Temporal Association of Protamine 1 with the Inner Nuclear Membrane Protein Lamin B Receptor during Spermiogenesis by Mylonis, Ilias, Drosou, Victoria, Brancorsini, Stefano, Nikolakaki, Eleni, Sassone-Corsi, Paolo, Giannakouros, Thomas

“…During mammalian spermiogenesis, histones are replaced by transition proteins, which are in turn replaced by protamines P1 and P2. P1 protamine contains a…”
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Processing of the small GTP-binding protein SpYPT1p in Schizosaccharomyces pombe and in mammalian COS cells by Giannakouros, T, Newman, C M, Armstrong, J, Magee, A I

“…SpYPT1p belongs to a family of ras-like GTP-binding proteins which is believed to be involved in the regulation of intracellular vesicular trafficking. We have…”
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Inhibition of protein synthesis by acetyl-coenzyme A in a cell-free system: possible involvement of protein acetylation in the regulation of translation by Nikolakaki, H, Giannakouros, T, Georgatsos, J G

“…Acetyl-coenzyme A (CoASAc) inhibits the rate of incorporation of amino acid into protein in a cell-free system of mouse liver. The effect is more pronounced…”
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Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1 by Mylonis, Ilias, Giannakouros, Thomas

“…The serine/arginine subfamily of protein kinases has been conserved throughout evolution and its members are thought to play important roles in the regulation…”
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SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1 by Nikolakaki, Eleni, Chalepakis, George, Kruft, Volker, Chevaillier, Philippe, Giannakouros, Thomas

“…Arginine/serine protein kinases constitute a novel class of enzymes that can modify arginine/serine (RS) dipeptide motifs. SR splicing factors that are…”
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Regulation of Alternative Splicing of Human Tau Exon 10 by Phosphorylation of Splicing Factors by Hartmann, Annette M., Rujescu, Dan, Giannakouros, Thomas, Nikolakaki, Eleni, Goedert, Michel, Mandelkow, Eva-Maria, Gao, Qing Sheng, Andreadis, Athena, Stamm, Stefan

“…Tau is a microtubule-associated protein whose transcript undergoes regulated splicing in the mammalian nervous system. Exon 10 of the gene is an alternatively…”
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Phosphorylation by LAMMER Protein Kinases:  Determination of a Consensus Site, Identification of In Vitro Substrates, and Implications for Substrate Preferences by Nikolakaki, Eleni, Du, Cheng, Lai, Jack, Giannakouros, Thomas, Cantley, Lew, Rabinow, Leonard

“…LAMMER protein kinases are ubiquitous throughout eukaryotes, including multiple paralogues in mammals. Members are characterized by similar overall structure…”
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Cloning and Characterization of an Alternatively Spliced Form of SR Protein Kinase 1 That Interacts Specifically with Scaffold Attachment Factor-B by Nikolakaki, Eleni, Kohen, Rachel, Hartmann, Annette M., Stamm, Stefan, Georgatsou, Elena, Giannakouros, Thomas

“…Serine/arginine protein kinases have been conserved throughout evolution and are thought to play important roles in the regulation of mRNA processing, nuclear…”
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Functional potential of P2P-R: A role in the cell cycle and cell differentiation related to its interactions with proteins that bind to matrix associated regions of DNA? by Scott, Robert E., Giannakouros, Thomas, Gao, Sizhi, Peidis, Philippos

“…P2P‐R is the alternately spliced product of the P2P‐R/PACT gene in that P2P‐R lacks one exon encoding 34 amino acids. The 250 kDa P2P‐R protein is the…”
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SRPK1 and LBR Protein Kinases Show Identical Substrate Specificities by Papoutsopoulou, Stamatia, Nikolakaki, Eleni, Giannakouros, Thomas

“…Arginine/serine protein kinases constitute a novel class of enzymes that can modify arginine/serine (RS) dipeptide motifs. SR splicing factors that are…”
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A Nuclear Envelope-associated Kinase Phosphorylates Arginine-Serine Motifs and Modulates Interactions between the Lamin B Receptor and Other Nuclear Proteins by Nikolakaki, E, Simos, G, Georgatos, S D, Giannakouros, T

“…Previous studies have identified a subassembly of nuclear envelope proteins, termed “the LBR complex.” This complex includes the lamin B receptor protein…”
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Mitotic phosphorylation of the lamin B receptor by a serine/arginine kinase and p34(cdc2) by Nikolakaki, E, Meier, J, Simos, G, Georgatos, S D, Giannakouros, T

“…The lamin B receptor (LBR) is an integral protein of the inner nuclear membrane that is modified at interphase by a nuclear envelope-bound protein kinase. This…”
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Purification and characterization of a dimer form of the cAMP-dependent protein kinase from mouse liver cytosol by Nikolakaki, E, Fissentzidis, A, Giannakouros, T, Georgatsos, J G

“…A protein kinase that phosphorylates histones and polysomal proteins was partially purified from mouse liver cytosol. The active enzyme has a molecular mass of…”
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Protein prenylation in Schizosaccharomyces pombe by Giannakouros, Thomas, Armstrong, John, Magee, Anthony I.

“…S. pombe is shown to be a powerful system for studies concerning attachment or polyisoprenoid moieties to proteins, due to its ability to take up exogenous…”
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