Search Results - "GIANDOMENICO, C. M"

Current Status of Platinum-Based Antitumor Drugs by Wong, Ernest, Giandomenico, Christen M.

“…Wong and Giandomenico give an update of the platinum-based drugs currently in human clinical trials and present an overview of the design of new compounds…”
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Ammine/amine platinum(IV) dicarboxylates : a novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cell lines by KELLAND, L. R, MURRER, B. A, ABEL, G, GIANDOMENICO, C. M, MISTRY, P, HARRAP, K. R

“…Using a panel of six human ovarian carcinoma cell lines varying by two orders of magnitude in terms of cisplatin cytotoxicity, we have investigated the in…”
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Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin by ORR, R. M, O'NEILL, C. F, NICOLSON, M. C, BARNARD, C. F. J, MURRER, B. A, GIANDOMENICO, C. M, VOLLANO, J. F, HARRAP, K. R

“…Seventeen alkylamine ammine dicarboxylatodichloroplatinum(IV) complexes of general structure c,t,c-[PtCl2(OCOR1)2NH3(RNH2)], where R = aliphatic or alicyclic…”
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Potential models of the interactions between nitrogen-containing heterocycles and the active catalyst sites in heterogeneous hydrodenitrogenation catalysts by Eisenstadt, A, Giandomenico, C. M, Frederick, M. F, Laine, R. M

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Combined modality treatment with ternary Cu(II) complexes and X rays by O'Hara, J A, Douple, E B, Abrams, M J, Giandomenico, C M, Bradley, F C, McElligott, M A, Caruso, F S

“…Ternary Cu(II) complexes with bidentate malonato- and heterocyclic amine ligands were tested with regard to cytotoxicity and potentiation of x-ray induced cell…”
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Nucleophilic catalysis of the migratory insertion of carbon monoxide. Evidence for a dissociative trapping mechanism by Webb, Steven L, Giandomenico, Christen M, Halpern, Jack

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Potentiation of radiation-induced cell kill by synthetic metalloporphyrins by O'Hara, J A, Douple, E B, Abrams, M J, Picker, D J, Giandomenico, C M, Vollano, J F

“…The effects of the combination of several meso-substituted, water soluble metalloporphyrins with ionizing radiation on hypoxic and oxic monolayers of Chinese…”
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3,4,3′, 4′-Tetrachloro Azoxybenzene and Azobenzene: Potent Inducers of Aryl Hydrocarbon Hydroxylase by Poland, Alan, Glover, Edward, Kende, Andrew S., DeCamp, Mark, Giandomenico, Christen M.

“…Two unwanted contaminants, 3,4,3′,4′-tetrachloroazobenzene (TCAOB) and 3,4,3′,4′-tetrachloroazobenzene (TCAB), formed in the commercial synthesis of…”
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Facile N-1 protection of cyclam, cyclen and 1,4,7-triazacyclononane by Yang, Wen, Giandomenico, Christen M., Sartori, Michael, Moore, Dennis A.

“…An exceptionally high yielding method for the tri-protection of cyclam and cyclen using ethyl trifluoroacetate is described. The selective reaction also…”
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Platinum coordination complexes which circumvent cisplatin resistance by Harrap, K R, Kelland, L R, Jones, M, Goddard, P M, Orr, R M, Morgan, S E, Murrer, B A, Abrams, M J, Giandomenico, C M, Cobbleigh, T

“…In the search for a platinum complex capable of oral administration, the poor bioavailability of established drugs has been circumvented by the discovery of a…”
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Carboxylation of Kinetically Inert Platinum(IV) Hydroxy Complexes. An Entr.acte.ee into Orally Active Platinum(IV) Antitumor Agents by Giandomenico, Christen M, Abrams, Michael J, Murrer, Barry A, Vollano, Jean F, Rheinheimer, Melanie I, Wyer, Sandra B, Bossard, Gerald E, Higgins, John D

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Molecular structure and ligand-exchange reactions of trichlorotris(tert-butyl isocyanide)vanadium(III). Synthesis of the hexakis(tert-butyl isocyanide)vanadium(II) cation by Silverman, Lance D, Dewan, John C, Giandomenico, Christen M, Lippard, Stephen J

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