Search Results - "GHOSH, SANKAR KUMAR"

Modulation of L-Arginine-Arginase Metabolic Pathway Enzymes: Immunocytochemistry and mRNA Expression in Peripheral Blood and Tissue Levels in Head and Neck Squamous Cell Carcinomas in North East India by Srivastava, Shilpee, Ghosh, Sankar Kumar

“…Background: Arginine may play important roles in tumor progression by providing ornithine for polyamine biosynthesis, required for cell growth. The aim of this…”
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Polymorphisms of XRCC1 and XRCC2 DNA Repair Genes and Interaction with Environmental Factors Influence the Risk of Nasopharyngeal Carcinoma in Northeast India by Singh, Seram Anil, Ghosh, Sankar Kumar

“…Multiple genetic and environmental factors have been reported to play key role in the development of nasopharyngeal carcinoma (NPC). Here, we investigated…”
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A murine model of type 2 diabetes mellitus developed using a combination of high fat diet and multiple low doses of streptozotocin treatment mimics the metabolic characteristics of type 2 diabetes mellitus in humans by Nath, Sayantan, Ghosh, Sankar Kumar, Choudhury, Yashmin

“…A murine model of type 2 diabetes mellitus was used to compare the antidiabetic effects of the dipeptidyl peptidase-4 (DPP4) inhibitor vildagliptin and…”
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Promoter Hypermethylation Profiling Identifies Subtypes of Head and Neck Cancer with Distinct Viral, Environmental, Genetic and Survival Characteristics by Choudhury, Javed Hussain, Ghosh, Sankar Kumar

“…Epigenetic and genetic alteration plays a major role to the development of head and neck squamous cell carcinoma (HNSCC). Consumption of tobacco…”
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Whole exome sequencing identifies the potential role of genes involved in p53 pathway in Nasopharyngeal Carcinoma from Northeast India by Laskar, Shaheen, Das, Raima, Kundu, Sharbadeb, Saha, Amrita, Nandi, Nilashis, Choudhury, Yashmin, Kumar Ghosh, Sankar

“…•p53 pathway harborsthe maximum percentage of clinically deleterious variants.•rs138941861 in STEAP3 gene was the most deleterious exonic unique-case…”
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Molecular Epidemiology of Amoebiasis: A Cross-Sectional Study among North East Indian Population by Nath, Joyobrato, Ghosh, Sankar Kumar, Singha, Baby, Paul, Jaishree

“…Epidemiological studies carried out using culture or microscopy in most of the amoebiasis endemic developing countries, yielded confusing results since none of…”
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Screening of 185DelAG, 1014DelGT and 3889DelAG BRCA1 Mutations in Breast Cancer Patients from North-East India by Hansa, Jagadish, Kannan, Ravi, Ghosh, Sankar Kumar

“…Around 1.35 million people of worldwide suffer from breast cancer each year, whereas in India, 1 in every 17 women develops the disease. Mutations of the…”
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Epigenetic, genetic and environmental interactions in esophageal squamous cell carcinoma from northeast India by Talukdar, Fazlur Rahman, Ghosh, Sankar Kumar, Laskar, Ruhina Shirin, Mondal, Rosy

“…Esophageal squamous cell carcinoma (ESCC) develops as a result of complex epigenetic, genetic and environmental interactions. Epigenetic changes like, promoter…”
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Genome-wide analysis of mammary gland shows modulation of transcriptome landscape with alternative splice variants in Staphylococcus aureus mastitis in mice by Mitra, Susweta Das, Ganaie, Feroze, Bankar, Kiran, Velu, Dhanikachalam, Mani, Bhuvana, Vasudevan, Madavan, Shome, Rajeswari, Rahman, Habibur, Kumar Ghosh, Sankar, Shome, Bibek Ranjan

“…•The study depicts the genome-wide changes in alternative splicing in S. aureus IMI.•RNA-seq analysis identified 30% more splice variants than the reference…”
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MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions by Bhowmik, Aditi, Das, Sambuddha, Bhattacharjee, Abhinandan, Choudhury, Biswadeep, Naiding, Momota, Deka, Sujata, Ghosh, Sankar Kumar, Choudhury, Yashmin

“…Background: Polymorphisms in the MDM2 309 (T>G) and TP53 72 (G>C) genes are reported to increase the susceptibility to head and neck cancer (HNC) in various…”
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Application and optimization of minimally invasive cell-free DNA techniques in oncogenomics by Kumar, Manish, Choudhury, Yashmin, Ghosh, Sankar Kumar, Mondal, Rosy

“…The conventional method of measuring biomarkers in malignant tissue samples has already given subversive growth in cancer diagnosis, prognosis, and therapy…”
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p16 Expression as a Surrogate Marker for HPV Infection in Esophageal Squamous Cell Carcinoma can Predict Response to Neo-Adjuvant Chemotherapy by Kumar, Rajeev, Ghosh, Sankar Kumar, Verma, Akalesh Kumar, Talukdar, Anuradha, Deka, Monoj Kumar, Wagh, Mira, Bahar, H.M. Iqbal, Tapkire, Ritesh, Chakraborty, Kali Pankaj, Kannan, R. Ravi

“…Background: Esophageal squamous cell carcinoma (ESCC) is a common cancer in the north east of India. The present study concerned the prevalence of human…”
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Influence of the CYP1A1 T3801C Polymorphism on Tobacco and Alcohol-Associated Head and Neck Cancer Susceptibility in Northeast India by Singh, Seram Anil, Choudhury, Javed Hussain, Kapfo, Wetetsho, Kundu, Sharbadeb, Dhar, Bishal, Laskar, Shaheen, Das, Raima, Kumar, Manish, Ghosh, Sankar Kumar

“…Background: Tobacco and alcohol contain or may generate carcinogenic compounds related to cancers. CYP1A1 enzymes act upon these carcinogens before elimination…”
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The GSTM1 and GSTT1 Null Genotypes Increase the Risk for Type 2 Diabetes Mellitus and the Subsequent Development of Diabetic Complications: A Meta-analysis by Nath, Sayantan, Das, Sambuddha, Bhowmik, Aditi, Ghosh, Sankar Kumar, Choudhury, Yashmin

“…Studies pertaining to association of GSTM1 and GSTT1 null genotypes with risk of T2DM and its complications were often inconclusive, thus spurring the present…”
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Quick diagnosis of female genital tuberculosis using multiplex fast polymerase chain reaction in Southern Assam, India by Ghosh, Sankar Kumar, Mondal, Rosy

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Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India by Kumar, Manish, Srivastava, Shilpee, Singh, Seram Anil, Das, Anup Kumar, Das, Ganesh Chandra, Dhar, Bishal, Ghosh, Sankar Kumar, Mondal, Rosy

“…Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the…”
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Mitochondrial DNA copy number and risk of oral cancer: a report from Northeast India by Mondal, Rosy, Ghosh, Sankar Kumar, Choudhury, Javed Hussain, Seram, Anil, Sinha, Kavita, Hussain, Marine, Laskar, Ruhina Shirin, Rabha, Bijuli, Dey, Pradip, Ganguli, Sabitri, Nathchoudhury, Monisha, Talukdar, Fazlur Rahman, Chaudhuri, Biswadeep, Dhar, Bishal

“…Oral squamous cell carcinoma (OSCC) is the sixth most common cancer globally. Tobacco consumption and HPV infection, both are the major risk factor for the…”
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Association of mitochondrial D-loop mutations with GSTM1 and GSTT1 polymorphisms in oral carcinoma: A case control study from Northeast India by Mondal, Rosy, Ghosh, Sankar Kumar, Talukdar, Fazlur Rahman, Laskar, Ruhina Shirin

“…Summary Objectives Mitochondrial dysfunction is a hallmark of cancer cells. Tobacco consumption in various forms is one of the major risk factors for the…”
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Low level of BRCA2 in peripheral blood lymphocytes is associated with an increased risk for head and neck squamous cell carcinoma (HNSCC) in a population of North-East India: a case-control study by Das, Sambuddha, Bhowmik, Aditi, Bhattacharjee, Abhinandan, Choudhury, Biswadeep, Naiding, Momota, Dhar, Bishal, Laskar, Agniv Kr, Pandit, Jayeeta, Ghosh, Sankar Kumar, Choudhury, Yashmin

“…We investigated the role of DNA repair proteins breast cancer susceptibility 2 (BRCA2), xeroderma pigmentosum group D (XPD) and apurinic/apyrimidinic…”
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Species specific mitochondrial Cytochrome c oxidase gene sequence of Manipuri pony by DEVI, KSH. MIRANDA, AHANTHEM, MONIKA, GHOSH, SANKAR KUMAR

“…The Manipuri pony, a unique indigenous horse breed of India, is known for its fastness, intelligence, surefooted moves and high endurance. The use of DNA…”
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