Search Results - "GHOSH, AUYON J"

Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies by Moll, Matthew, Hobbs, Brian D, Menon, Aravind, Ghosh, Auyon J, Putman, Rachel K, Hino, Takuya, Hata, Akinori, Silverman, Edwin K, Quackenbush, John, Castaldi, Peter J, Hersh, Craig P, McGeachie, Michael J, Sin, Don D, Tal-Singer, Ruth, Nishino, Mizuki, Hatabu, Hiroto, Hunninghake, Gary M, Cho, Michael H

“…Interstitial lung abnormalities (ILA) are radiologic findings that may progress to idiopathic pulmonary fibrosis (IPF). Blood gene expression profiles can…”
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Vitamin D deficiency is associated with respiratory symptoms and airway wall thickening in smokers with and without COPD: a prospective cohort study by Ghosh, Auyon J, Moll, Matthew, Hayden, Lystra P, Bon, Jessica, Regan, Elizabeth, Hersh, Craig P

“…Previous studies have established a higher prevalence of vitamin D deficiency in patients with COPD, but the relationship between vitamin D levels and COPD…”
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Relative contributions of family history and a polygenic risk score on COPD and related outcomes: COPDGene and ECLIPSE studies by Moll, Matthew, Lutz, Sharon M., Ghosh, Auyon J., Sakornsakolpat, Phuwanat, Hersh, Craig P., Beaty, Terri H., Dudbridge, Frank, Tobin, Martin D., Mittleman, Murray A., Silverman, Edwin K., Hobbs, Brian D., Cho, Michael H.

“…IntroductionFamily history is a risk factor for chronic obstructive pulmonary disease (COPD). We previously developed a COPD risk score from genome-wide…”
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Blocking hyaluronan synthesis alleviates acute lung allograft rejection by Imani, Jewel, Liu, Kaifeng, Cui, Ye, Assaker, Jean-Pierre, Han, Junwen, Ghosh, Auyon J, Ng, Julie, Shrestha, Shikshya, Lamattina, Anthony M, Louis, Pierce H, Hentschel, Anne, Esposito, Anthony J, Rosas, Ivan O, Liu, Xiaoli, Perrella, Mark A, Azzi, Jamil, Visner, Gary, El-Chemaly, Souheil

“…Lung allograft rejection results in the accumulation of low-molecular weight hyaluronic acid (LMW-HA), which further propagates inflammation and tissue injury…”
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Increased Odds of Death for Patients with Interstitial Lung Disease and COVID-19: A Case-Control Study by Esposito, Anthony J, Menon, Aravind A, Ghosh, Auyon J, Putman, Rachel K, Fredenburgh, Laura E, El-Chemaly, Souheil Y, Goldberg, Hilary J, Baron, Rebecca M, Hunninghake, Gary M, Doyle, Tracy J

“…Coronavirus disease (COVID-19) is an international public health emergency. Although the prevalence of chronic respiratory disease in patients with COVID-19…”
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Reply to Chan: Identification of Alpha-1 Antitrypsin-Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement by Fraughen, Daniel D, Ghosh, Auyon J, Carroll, Tomás P, McElvaney, Noel G

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Comorbidity-Based Clusters Contain Chaos in COPD by Ghosh, Auyon J., Hobbs, Brian D.

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Airway Pressure Release Ventilation in Acute Respiratory Failure Due to COVID-19: When One Door Closes by Ghosh, Auyon J., Nieman, Gary F., Habashi, Nader M.

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Association Between USMLE Step 1 Scores and In-Training Examination Performance: A Meta-Analysis by Panda, Nikhil, Bahdila, Dania, Abdullah, Abeer, Ghosh, Auyon J., Lee, Sun Yeop, Feldman, William B.

“…On February 12, 2020, the sponsors of the United States Medical Licensing Examination announced that Step 1 will transition to pass/fail scoring in 2022. Step…”
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Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains by Ghosh, Auyon J, Saferali, Aabida, Lee, Sool, Chase, Robert, Moll, Matthew, Morrow, Jarrett, Yun, Jeong, Castaldi, Peter J, Hersh, Craig P

“…COPD can be assessed using multidimensional grading systems with components from three domains: pulmonary function tests, symptoms and systemic features…”
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Protective ventilation in a pig model of acute lung injury: timing is as important as pressure by Ramcharran, Harry, Bates, Jason H T, Satalin, Joshua, Blair, Sarah, Andrews, Penny L, Gaver, Donald P, Gatto, Louis A, Wang, Guirong, Ghosh, Auyon J, Robedee, Benjamin, Vossler, James, Habashi, Nader M, Daphtary, Nirav, Kollisch-Singule, Michaela, Nieman, Gary F

“…Ventilator-induced lung injury (VILI) is a significant risk for patients with acute respiratory distress syndrome (ARDS). Management of the patient with ARDS…”
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Augmentation Therapy for Severe Alpha-1 Antitrypsin Deficiency Improves Survival and Is Decoupled from Spirometric Decline-A Multinational Registry Analysis by Fraughen, Daniel D, Ghosh, Auyon J, Hobbs, Brian D, Funk, Georg-Christian, Meischl, Tobias, Clarenbach, Christian F, Sievi, Noriane A, Schmid-Scherzer, Karin, McElvaney, Oliver J, Murphy, Mark P, Roche, Adam D, Clarke, Louise, Strand, Matthew, Vafai-Tabrizi, Florian, Kelly, Geraldine, Gunaratnam, Cedric, Carroll, Tomás P, McElvaney, Noel G

“…Intravenous plasma-purified alpha-1 antitrypsin (IV-AAT) has been used as therapy for alpha-1 antitrypsin deficiency (AATD) since 1987. Previous trials (RAPID…”
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Recent advancements in understanding the genetic involvement of alpha-1 antitrypsin deficiency associated lung disease: a look at future precision medicine approaches by Ghosh, Auyon J, Hobbs, Brian D

“…Alpha-1 antitrypsin deficiency occurs in individuals with deleterious genetic mutations on both chromosomes (maternal and paternal) in , the gene encoding the…”
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Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis by Ghosh, Auyon J, Moll, Matthew, Hobbs, Brian D, Cardwell, Jonathan, Saferali, Aabida, Castaldi, Peter J, Cho, Michael H, Silverman, Edwin K, Yang, Ivana V, Hersh, Craig P

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Interstitial Lung Abnormalities, Emphysema, and Spirometry in Smokers by Menon, Aravind A., Putman, Rachel K., Sanders, Jason L., Hino, Takuya, Hata, Akinori, Nishino, Mizuki, Ghosh, Auyon J., Ash, Samuel Y., Rosas, Ivan O., Cho, Michael H., Lynch, David A., Washko, George R., Silverman, Edwin K., Hatabu, Hiroto, Hunninghake, Gary M.

“…Most pulmonary conditions reduce FVC, but studies of patients with combined pulmonary fibrosis and emphysema demonstrate that reductions in FVC are less than…”
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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities by Moll, Matthew, Peljto, Anna L, Kim, John S, Xu, Hanfei, Debban, Catherine L, Chen, Xianfeng, Menon, Aravind, Putman, Rachel K, Ghosh, Auyon J, Saferali, Aabida, Nishino, Mizuki, Hatabu, Hiroto, Hobbs, Brian D, Hecker, Julian, McDermott, Gregory, Sparks, Jeffrey A, Wain, Louise V, Allen, Richard J, Tobin, Martin D, Raby, Benjamin A, Chun, Sung, Silverman, Edwin K, Zamora, Ana C, Ortega, Victor E, Garcia, Christine K, Barr, R Graham, Bleecker, Eugene R, Meyers, Deborah A, Kaner, Robert J, Rich, Stephen S, Manichaikul, Ani, Rotter, Jerome I, Dupuis, Josée, O'Connor, George T, Fingerlin, Tasha E, Hunninghake, Gary M, Schwartz, David A, Cho, Michael H

“…In addition to rare genetic variants and the locus, common genetic variants contribute to idiopathic pulmonary fibrosis (IPF) risk. The predictive power of…”
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Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease by Moll, Matthew, Sordillo, Joanne E., Ghosh, Auyon J., Hayden, Lystra P., McDermott, Gregory, McGeachie, Michael J., Dahlin, Amber, Tiwari, Anshul, Manmadkar, Monica G., Abston, Eric D., Pavuluri, Chandan, Saferali, Aabida, Begum, Sofina, Ziniti, John P., Gulsvik, Amund, Bakke, Per S., Aschard, Hugues, Iribarren, Carlos, Hersh, Craig P., Sparks, Jeffrey A., Hobbs, Brian D., Lasky-Su, Jessica A., Silverman, Edwin K., Weiss, Scott T., Wu, Ann Chen, Cho, Michael H.

“…Asthma and chronic obstructive pulmonary disease (COPD) have distinct and overlapping genetic and clinical features. We sought to test the hypothesis that…”
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Alpha-1 Antitrypsin MZ Heterozygosity Is an Endotype of Chronic Obstructive Pulmonary Disease by Ghosh, Auyon J, Hobbs, Brian D, Moll, Matthew, Saferali, Aabida, Boueiz, Adel, Yun, Jeong H, Sciurba, Frank, Barwick, Lucas, Limper, Andrew H, Flaherty, Kevin, Criner, Gerard, Brown, Kevin K, Wise, Robert, Martinez, Fernando J, Lomas, David, Castaldi, Peter J, Carey, Vincent J, DeMeo, Dawn L, Cho, Michael H, Silverman, Edwin K, Hersh, Craig P

“…Multiple studies have demonstrated an increased risk of chronic obstructive pulmonary disease (COPD) in heterozygous carriers of the AAT (alpha-1 antitrypsin)…”
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Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease by Moll, Matthew, Boueiz, Adel, Ghosh, Auyon J, Saferali, Aabida, Lee, Sool, Xu, Zhonghui, Yun, Jeong H, Hobbs, Brian D, Hersh, Craig P, Sin, Don D, Tal-Singer, Ruth, Silverman, Edwin K, Cho, Michael H, Castaldi, Peter J

“…The ability of peripheral blood biomarkers to assess chronic obstructive pulmonary disease (COPD) risk and progression is unknown. Genetics and gene expression…”
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Intermediate versus standard dose heparin prophylaxis in COVID-19 ICU patients: A propensity score-matched analysis by Moll, Matthew, Zon, Rebecca L., Sylvester, Katelyn W., Rimsans, Jessica, Chen, Evan C., Ghosh, Auyon J., Abston, Eric, Kim, Andy, Rutherford, Henry, Mitre, Xhoi, Hakim, Aaron, Connell, Nathan T., Battinelli, Elisabeth, Fredenburgh, Laura E., Baron, Rebecca M., Hobbs, Brian D., Cho, Michael H., Mittleman, Murray A., Woolley, Ann E., Connors, Jean M.

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