Search Results - "GHOLKAR, A"

Stent-assisted coiling versus coiling alone in unruptured intracranial aneurysms in the matrix and platinum science trial: safety, efficacy, and mid-term outcomes by Hetts, S W, Turk, A, English, J D, Dowd, C F, Mocco, J, Prestigiacomo, C, Nesbit, G, Ge, S G, Jin, J N, Carroll, K, Murayama, Y, Gholkar, A, Barnwell, S, Lopes, D, Johnston, S C, McDougall, C

“…Stent-assisted coiling may result in less aneurysm recanalization but more complications than coiling alone. We evaluated outcomes of coiling with and without…”
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Bioactive versus bare platinum coils in the treatment of intracranial aneurysms: the MAPS (Matrix and Platinum Science) trial by McDougall, C G, Johnston, S Claiborne, Gholkar, A, Barnwell, S L, Vazquez Suarez, J C, Massó Romero, J, Chaloupka, J C, Bonafe, A, Wakhloo, A K, Tampieri, D, Dowd, C F, Fox, A J, Imm, S J, Carroll, K, Turk, A S

“…The ability of polymer-modified coils to promote stable aneurysm occlusion after endovascular treatment is not well-documented. Angiographic aneurysm…”
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Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division by Gholkar, Ankur A., Cheung, Keith, Williams, Kevin J., Lo, Yu-Chen, Hamideh, Shadia A., Nnebe, Chelsea, Khuu, Cindy, Bensinger, Steven J., Torres, Jorge Z.

“…The sterol regulatory element-binding protein (SREBP) transcription factors have become attractive targets for pharmacological inhibition in the treatment of…”
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HydroCoil Endovascular Aneurysm Occlusion and Packing Study (HELPS Trial): Procedural Safety and Operator-Assessed Efficacy Results by White, P.M, Lewis, S.C, Nahser, H, Sellar, R.J, Goddard, T, Gholkar, A, on behalf of HELPS Trial Collaboration

“…Coated coils have been in clinical use for several years without robust evidence to determine their safety/efficacy. The HydroCoil Endovascular Aneurysm…”
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The STARD9/Kif16a Kinesin Associates with Mitotic Microtubules and Regulates Spindle Pole Assembly by Torres, Jorge Z., Summers, Matthew K., Peterson, David, Brauer, Matthew J., Lee, James, Senese, Silvia, Gholkar, Ankur A., Lo, Yu-Chen, Lei, Xingye, Jung, Kenneth, Anderson, David C., Davis, David P., Belmont, Lisa, Jackson, Peter K.

“…During cell division, cells form the microtubule-based mitotic spindle, a highly specialized and dynamic structure that mediates proper chromosome transmission…”
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Treatment of poor-grade subarachnoid hemorrhage trial by Mitra, D, Gregson, B, Jayakrishnan, V, Gholkar, A, Vincent, A, White, P, Mitchell, P

“…Management of poor-grade subarachnoid hemorrhage is based on limited evidence from small single-center retrospective observational studies. The purpose of this…”
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The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division by Gholkar, Ankur A., Senese, Silvia, Lo, Yu-Chen, Vides, Edmundo, Contreras, Ely, Hodara, Emmanuelle, Capri, Joseph, Whitelegge, Julian P., Torres, Jorge Z.

“…Mid1 and Mid2 are ubiquitin ligases that regulate microtubule dynamics and whose mutation is associated with X-linked developmental disorders. We show that…”
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Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development by Senese, S, Lo, Y C, Huang, D, Zangle, T A, Gholkar, A A, Robert, L, Homet, B, Ribas, A, Summers, M K, Teitell, M A, Damoiseaux, R, Torres, J Z

“…Cancer cell proliferation relies on the ability of cancer cells to grow, transition through the cell cycle, and divide. To identify novel chemical probes for…”
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A unique insertion in STARD9's motor domain regulates its stability by Senese, Silvia, Cheung, Keith, Lo, Yu-Chen, Gholkar, Ankur A, Xia, Xiaoyu, Wohlschlegel, James A, Torres, Jorge Z

“…STARD9 is a largely uncharacterized mitotic kinesin and putative cancer target that is critical for regulating pericentriolar material cohesion during bipolar…”
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Counterpoint-target aneurysm recurrence: measuring what matters by McDougall, C G, Johnston, S C, Gholkar, A, Turk, A S

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HydroCoils Are Associated with Lower Angiographic Recurrence Rates Than Are Bare Platinum Coils in Treatment of "Difficult-to-Treat" Aneurysms: A Post Hoc Subgroup Analysis of the HELPS Trial by Brinjikji, W, White, P M, Nahser, H, Wardlaw, J, Sellar, R, Gholkar, A, Cloft, H J, Kallmes, D F

“…The HydroCoil Endovascular Aneurysm Occlusion and Packing Study was a randomized controlled trial that compared HydroCoils to bare platinum coils. Using data…”
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White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer’s disease, vascular dementia, and normal aging by Barber, R, Scheltens, P, Gholkar, A, Ballard, C, McKeith, I, Ince, P, Perry, R, O’Brien, J

“…OBJECTIVES Alzheimer’s disease and vascular dementia are associated with an increase in changes in white matter on MRI. The aims were to investigate whether…”
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Alexander disease : Ventricular garlands and abnormalities of the medulla and spinal cord by VAN DER KNAAP, M. S, RAMESH, V, BARKHOF, F, SALOMONS, G. S, SCHIFFMANN, R, BLASER, S, KYLLERMAN, M, GHOLKAR, A, ELLISON, D. W, VAN DER VOORN, J. P, VAN DOOREN, S. J. M, JAKOBS, C

“…Alexander disease is most commonly associated with macrocephaly and, on MRI, a leukoencephalopathy with frontal preponderance. The disease is caused by…”
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MRI volumetric study of dementia with Lewy bodies : A comparison with AD and vascular dementia by BARBER, R, BALLARD, C, MCKEITH, I. G, GHOLKAR, A, O'BRIEN, J. T

“…To compare global and regional atrophy on MRI in subjects with dementia with Lewy bodies (DLB), AD, vascular dementia (VaD), and normal aging. In addition, the…”
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Embolization of Residual Fistula Following Stereotactic Radiosurgery in Cerebral Arteriovenous Malformations by Hodgson, T.J, Kemeny, A.A, Gholkar, A, Deasy, N

“…Treatment of brain arteriovenous malformations (BAVMs) often requires a multitechnique approach. We present 2 cases of BAVM, in which initial stereotactic…”
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Single-Center Experience of Cerecyte Coils in the Treatment of Intracranial Aneurysms: Initial Experience and Early Follow-Up Results by Butteriss, D, Gholkar, A, Mitra, D, Birchall, D, Jayakrishnan, V

“…Endovascular treatment of intracranial aneurysms using platinum coils is effective, but uncommonly aneurysms recur. New-generation coils, such as Cerecyte, aim…”
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Atrophy of the putamen in dementia with Lewy bodies but not Alzheimer's disease: An MRI study by COUSINS, D. A, BURTON, E. J, BURN, D, GHOLKAR, A, MCKEITH, I. G, O'BRIEN, J. T

“…To compare the volume of the putamen on MRI in subjects with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) and age-matched normal control…”
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Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia by O'BRIEN, J. T, PALING, S, BARBER, R, WILLIAMS, E. D, BALLARD, C, MCKEITH, I. G, GHOLKAR, A, CRUM, W. R, ROSSOR, M. N, FOX, N. C

“…The authors determined rates of brain atrophy, as assessed by the boundary shift integral on serial MRI, in patients with dementia with Lewy Bodies (DLB, n =…”
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Medial temporal lobe atrophy on MRI in dementia with Lewy bodies by BARBER, R, GHOLKAR, A, SCHELTENS, P, BALLARD, C, MCKEITH, I. G, O'BRIEN, J. T

“…To investigate whether medial temporal lobe atrophy (MTA) on MRI is less frequent in dementia with Lewy bodies (DLB) compared with AD and vascular dementia…”
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A comparison of medial and lateral temporal lobe atrophy in dementia with Lewy bodies and Alzheimer's disease: magnetic resonance imaging volumetric study by Barber, R, McKeith, I G, Ballard, C, Gholkar, A, O'Brien, J T

“…To compare medial and lateral temporal lobe atrophy on magnetic resonance imaging (MRI) in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD), and to…”
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