Search Results - "GHIARA, P"

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease by TELFORD, J. L, GHIARA, P, PAPINI, E, MONTECUCCO, C, PARENTE, L, RAPPUOLI, R, DELL'ORCO, M, COMANDUCCI, M, BURRONI, D, BUGNOLI, M, TECCE, M. F, CENSINI, S, COVACCI, A, ZHAOYING XIANG

“…The gram negative, microaerophilic bacterium Helicobacter pylori colonizes the human gastric mucosa and establishes a chronic infection that is tightly…”
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Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease by GHIARA, P, MARCHETTI, M, BLASER, M. J, TUMMURU, M. K. R, COVER, T. L, SEGAL, E. D, TOMPKINS, L. S, RAPPUOLI, R

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Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity by APPELMELK, B. J, SIMOONS-SMIT, I, GNHIARA, P, KUIPERS, E. J, BLOEMENA, E, TADEMA, T. M, TOWNSEND, R. R, TYAGARAJAN, K, CROTHERS, J. M, MONTEIRO, M. A, SAVIO, A, DE GRAAFF, J, NEGRINI, R, MCGHEE, J. R, MORAN, A. P, ASPINALL, G. O, FORTE, J. G, DE VRIES, T, QUAN, H, VERBOOM, T, MAASKANT, J. J

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Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection by GHIARA, P, ROSSI, M, RAPPUOLI, R, DEL GIUDICE, G, MARCHETTI, M, DI TOMMASO, A, VINDIGNI, C, CIAMPOLINI, F, COVACCI, A, TELFORD, J. L, DE MAGISTRIS, M. T, PIZZA, M

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Human Peritoneal Mesothelial Cells Produce Many Cytokines (Granulocyte Colony-Stimulating Factor [CSF], Granulocyte-Monocyte–CSF, Macrophage-CSF, Interleukin-1 [IL-1], and IL-6) and Are Activated and Stimulated to Grow by IL-1 by Lanfrancone, L., Boraschi, D., Ghiara, P., Falini, B., Grignani, F., Peri, G., Mantovani, A., Pelicci, P.G.

“…To investigate the role of peritoneal mesothelial cells in regulating hematopoiesis, as well as inflammation, healing, and tissue regeneration processes,…”
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Mouse model of Helicobacter pylori infection: studies of gastric function and ulcer healing by KONTUREK, P. C, BRZOZOWSKI, T, KONTUREK, S. J, STACHURA, J, KARCZEWSKA, E, PAJDO, R, GHIARA, P, HAHN, E. G

“…Background : Helicobacter pylori infection in humans is a major risk factor for peptic ulcer, but studies on the relation between H. pylori infection and…”
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A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae by Baldari, C., Murray, J.A., Ghiara, P., Cesareni, G., Galeotti, C.L.

“…Killer strains of Kluyveromyces lactis secrete a toxin which presumably is processed during secretion from a larger precursor. Analysis of the sequence of the…”
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Detoxification of the Helicobacter pylori cytotoxin by MANETTI, R, MASSARI, P, MARCHETTI, M, MAGAGNOLI, C, NUTI, S, LUPETTI, P, GHIARA, P, RAPPUOLI, R, TELFORD, J. L

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Autocrine Interleukin-1β Regulates Both Proliferation and Apoptosis in EL4-6.1 Thymoma Cells by Fratelli, Maddalena, Gagliardini, Valeria, Galli, Grazia, Gnocchi, Paola, Ghiara, Paolo, Ghezzi, Pietro

“…We demonstrate here that EL4-6.1 cells, a mouse thymoma that expresses high levels of membrane interleukin (IL)-1 receptors, produce IL-1β as an autocrine…”
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Cytokines in the viviparous reproduction of squamate reptiles: Interleukin-1α (IL-1α) and IL-1β in placental structures of a skink by Paulesu, L., Romagnoli, R., Marchetti, M., Cintorino, M., Ghiara, P., Guarino, F.M., Ghiara, G.

“…Placental viviparity is known in many species of squamate reptiles. Among these, some scincids have developed an epithelio-chorial chorio-allantoic placenta…”
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A short synthetic peptide fragment of human interleukin 1 with immunostimulatory but not inflammatory activity by Antoni, G, Presentini, R, Perin, F, Tagliabue, A, Ghiara, P, Censini, S, Volpini, G, Villa, L, Boraschi, D

“…Short peptide fragments of human and murine interleukin 1 (IL 1) were synthesized on the basis of their predicted exposure on the surface of the molecule in an…”
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Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat by Luheshi, G, Hopkins, S J, Lefeuvre, R A, Dascombe, M J, Ghiara, P, Rothwell, N J

“…Interleukin-1 (IL-1) acts centrally to induce fever and thermogenesis in rodents. The central actions of IL-1 alpha and IL-1 beta apparently involve different…”
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Differential binding of IL‐ 1α and IL‐ 1β to receptors on B and T cells by Scapigliati, G., Ghiara, P., Bartalini, M., Tagliabue, A., Boraschi, D.

“…The interleukin 1 receptors (IL‐1R) on the human B lymphoma RAJI and on the murine thymoma EL4‐6.1 have been characterized. Equilibrium binding analysis using…”
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A chimeric type II/type I interleukin-1 receptor can mediate interleukin-1 induction of gene expression in T cells by Heguy, A., Baldari, C.T., Censini, S., Ghiara, P., Telford, J.L.

“…The type I interleukin-1 receptor (IL-1R) is capable of transducing a signal resulting in promoter activation in T cells. This signal transduction is dependent…”
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The inflammatory response in CD1 mice shortly after infection with a CagA+/VacA+Helicobacter pylori strain by VAN DOORN, N. E. M, VAN REES, E. P, NAMAVAR, F, GHIARA, P, VANDENBROUCKEGRAULS, C. M. J. E, DE GRAAFF, J

“…To investigate the early events of Helicobacter pylori infection in a mouse model, CD1 mice were infected with a type I (CagA+/VacA+) H. pylori strain. Up to 4…”
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Gastric secretion and ulcer healing in mouse stomach infected with cytotoxin expressing strain of Helicobacter pylori by Brzozowski, T, Konturek, P C, Konturek, S J, Karczewska, E, Pajdo, R, Stachura, J, Ghiara, P, Hahn, E G

“…Helicobacter pylori (Hp) is a major risk factor of peptic ulcer but studies on the relation between Hp infection and gastric pathology are limited due to lack…”
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Enhancement of in vivo immune response by tumor necrosis factor by Ghiara, P, Boraschi, D, Nencioni, L, Ghezzi, P, Tagliabue, A

“…Interleukin 1 (IL-1) has been shown to regulate several immunologic functions. Since tumor necrosis factor (TNF) shares many biologic properties with IL-1, we…”
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19 IMMUNOGENICITY OF PURIFIED AND RECOMBINANT ANTIGENS OF HELICOBACTER PYLORI IN THE MOUSE by Oderde, G, Burroni, D, Bugnoli, M, Ghiara, P

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Depression of liver metabolism and induction of cytokine release by diphtheria and tetanus toxoids and pertussis vaccines: role of Bordetella pertussis cells in toxicity by Fantuzzi, G, Sironi, M, Delgado, R, Cantoni, L, Rizzardini, M, Carelli, M, Marsili, I, Ghiara, P, Ghezzi, P

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cag, a Pathogenicity Island of Helicobacter pylori, Encodes Type I-Specific and Disease-Associated Virulence Factors by Censini, Stefano, Lange, Christina, Xiang, Zhaoying, Crabtree, Jean E., Ghiara, Paolo, Borodovsky, Mark, Rappuoli, Rino, Covacci, Antonello

“…cagA, a gene that codes for an immunodominant antigen, is present only in Helicobacter pylori strains that are associated with severe forms of gastroduodenal…”
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