Search Results - "GHAVAMI, SAEID"

Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma by Barzegar Behrooz, Amir, Talaie, Zahra, Jusheghani, Fatemeh, Łos, Marek J, Klonisch, Thomas, Ghavami, Saeid

“…Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments, including surgery, chemotherapy, and radiation, are palliative at…”
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Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions by Gholizadeh, Shima, Shehata Draz, Mohamed, Zarghooni, Maryam, Sanati-Nezhad, Amir, Ghavami, Saeid, Shafiee, Hadi, Akbari, Mohsen

“…Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an essential role in various cellular processes, such as intercellular…”
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Investigating Programmed Cell Death and Tumor Invasion in a Three-Dimensional (3D) Microfluidic Model of Glioblastoma by Samiei, Ehsan, Seyfoori, Amir, Toyota, Brian, Ghavami, Saeid, Akbari, Mohsen

“…Glioblastoma multiforme (GBM) is a rapidly progressive and deadly form of brain tumor with a median survival rate of ~15 months. GBMs are hard to treat and…”
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Autophagy Activation in Asthma Airways Remodeling by McAlinden, Kielan D, Deshpande, Deepak A, Ghavami, Saeid, Xenaki, Dia, Sohal, Sukhwinder Singh, Oliver, Brian G, Haghi, Mehra, Sharma, Pawan

“…Current asthma therapies fail to target airway remodeling that correlates with asthma severity driving disease progression that ultimately leads to loss of…”
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Autophagy unraveled: Navigating cell fate and disease dynamics by Shojaei, Shahla, Ghavami, Saeid

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Alzheimer's Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia by Eshraghi, Mehdi, Adlimoghaddam, Aida, Mahmoodzadeh, Amir, Sharifzad, Farzaneh, Yasavoli-Sharahi, Hamed, Lorzadeh, Shahrokh, Albensi, Benedict C, Ghavami, Saeid

“…Alzheimer's disease (AD) is a debilitating neurological disorder, and currently, there is no cure for it. Several pathologic alterations have been described in…”
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Genetic polymorphisms of HOTAIR gene are associated with the risk of breast cancer in a sample of southeast Iranian population by Hassanzarei, Shekoufeh, Hashemi, Mohammad, Sattarifard, Hedieh, Hashemi, Seyed Mehdi, Bahari, Gholamreza, Ghavami, Saeid

“…There is an increasing body of evidence which highlights the critical functions of long non-coding RNAs in the carcinogenicity mechanism of a variety of…”
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Pleiotropic effects of statins: A focus on cancer by Ahmadi, Mazaher, Amiri, Shayan, Pecic, Stevan, Machaj, Filip, Rosik, Jakub, Łos, Marek J., Alizadeh, Javad, Mahdian, Reza, da Silva Rosa, Simone C., Schaafsma, Dedmer, Shojaei, Shahla, Madrakian, Tayyebeh, Zeki, Amir A., Ghavami, Saeid

“…The statin drugs (‘statins’) potently inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by competitively blocking the active site of the enzyme…”
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The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections by Mehrbod, Parvaneh, Ande, Sudharsana R., Alizadeh, Javad, Rahimizadeh, Shahrzad, Shariati, Aryana, Malek, Hadis, Hashemi, Mohammad, Glover, Kathleen K. M., Sher, Affan A., Coombs, Kevin M., Ghavami, Saeid

“…Virus infection induces different cellular responses in infected cells. These include cellular stress responses like autophagy and unfolded protein response…”
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Toll like receptor 4 and hepatocellular carcinoma; A systematic review by Sepehri, Zahra, Kiani, Zohre, Kohan, Farhad, Alavian, Seyed Moayed, Ghavami, Saeid

“…Toll like receptor 4 (TLR4) is an extracellular pathogen recognition receptor (PRR) which recognizes a wide range of pathogens and damage associated molecular…”
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Targeting cholesterol metabolism in glioblastoma: a new therapeutic approach in cancer therapy by Pirmoradi, Leila, Seyfizadeh, Nayer, Ghavami, Saeid, Zeki, Amir A, Shojaei, Shahla

“…Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor known with a poor survival rate despite current advances in the field of cancer…”
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Putative RNA Ligase RtcB Affects the Switch between T6SS and T3SS in Pseudomonas aeruginosa by Dadashi, Maryam, Chen, Lin, Nasimian, Ahmad, Ghavami, Saeid, Duan, Kangmin

“…The opportunistic pathogen is a significant cause of infection in immunocompromised individuals, cystic fibrosis patients, and burn victims. To benefit its…”
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Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets by Kotowski, Krzysztof, Rosik, Jakub, Machaj, Filip, Supplitt, Stanisław, Wiczew, Daniel, Jabłońska, Karolina, Wiechec, Emilia, Ghavami, Saeid, Dzięgiel, Piotr

“…Glycolysis is a crucial metabolic process in rapidly proliferating cells such as cancer cells. Phosphofructokinase-1 (PFK-1) is a key rate-limiting enzyme of…”
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Enhancing autophagy in Alzheimer's disease through drug repositioning by Eshraghi, Mehdi, Ahmadi, Mazaher, Afshar, Saeid, Lorzadeh, Shahrokh, Adlimoghaddam, Aida, Rezvani Jalal, Nahid, West, Ryan, Dastghaib, Sanaz, Igder, Somayeh, Torshizi, Seyed Reza Naeimi, Mahmoodzadeh, Amir, Mokarram, Pooneh, Madrakian, Tayyebeh, Albensi, Benedict C., Łos, Marek J., Ghavami, Saeid, Pecic, Stevan

“…Alzheimer's disease (AD) is one of the biggest human health threats due to increases in aging of the global population. Unfortunately, drugs for treating AD…”
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Autoimmune Hepatitis and Stellate Cells: An Insight into the Role of Autophagy by Golbabapour, Shahram, Bagheri-Lankarani, Kamran, Ghavami, Saeid, Geramizadeh, Bita

“…Autoimmune hepatitis is a necroinflammatory process of liver, featuring interface hepatitis by T cells, macrophages and plasma cells that invade to periportal…”
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The urgent need for integrated science to fight COVID-19 pandemic and beyond by Moradian, Negar, Ochs, Hans D, Sedikies, Constantine, Hamblin, Michael R, Camargo, Jr, Carlos A, Martinez, J Alfredo, Biamonte, Jacob D, Abdollahi, Mohammad, Torres, Pedro J, Nieto, Juan J, Ogino, Shuji, Seymour, John F, Abraham, Ajith, Cauda, Valentina, Gupta, Sudhir, Ramakrishna, Seeram, Sellke, Frank W, Sorooshian, Armin, Wallace Hayes, A, Martinez-Urbistondo, Maria, Gupta, Manoj, Azadbakht, Leila, Esmaillzadeh, Ahmad, Kelishadi, Roya, Esteghamati, Alireza, Emam-Djomeh, Zahra, Majdzadeh, Reza, Palit, Partha, Badali, Hamid, Rao, Idupulapati, Saboury, Ali Akbar, Jagan Mohan Rao, L, Ahmadieh, Hamid, Montazeri, Ali, Fadini, Gian Paolo, Pauly, Daniel, Thomas, Sabu, Moosavi-Movahed, Ali A, Aghamohammadi, Asghar, Behmanesh, Mehrdad, Rahimi-Movaghar, Vafa, Ghavami, Saeid, Mehran, Roxana, Uddin, Lucina Q, Von Herrath, Matthias, Mobasher, Bahram, Rezaei, Nima

“…The COVID-19 pandemic has become the leading societal concern. The pandemic has shown that the public health concern is not only a medical problem, but also…”
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Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease by YEGANEH, Behzad, WIECHEC, Emilia, GHAVAMI, Saeid, ANDE, Sudharsana R, SHARMA, Pawan, ADEL REZAEI MOGHADAM, POST, Martin, FREED, Darren H, HASHEMI, Mohammad, SHOJAEI, Shahla, ZEKI, Amir A

“…The cholesterol biosynthesis pathway, also known as the mevalonate (MVA) pathway, is an essential cellular pathway that is involved in diverse cell functions…”
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Inhibition of Autophagy Flux Promotes Secretion of Chondroitin Sulfate Proteoglycans in Primary Rat Astrocytes by Alizadeh, Javad, Kochan, Matthew M., Stewart, Vanessa D., Drewnik, Dennis A., Hannila, Sari S., Ghavami, Saeid

“…Following spinal cord injury (SCI), reactive astrocytes in the glial scar produce high levels of chondroitin sulfate proteoglycans (CSPGs), which are known to…”
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Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy by Alizadeh, Javad, da Silva Rosa, Simone C., Weng, Xiaohui, Jacobs, Joadi, Lorzadeh, Shahrokh, Ravandi, Amir, Vitorino, Rui, Pecic, Stevan, Zivkovic, Aleksandra, Stark, Holger, Shojaei, Shahla, Ghavami, Saeid

“…Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context…”
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Photodynamic N-TiO2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells by Moosavi, Mohammad Amin, Sharifi, Maryam, Ghafary, Soroush Moasses, Mohammadalipour, Zahra, Khataee, Alireza, Rahmati, Marveh, Hajjaran, Sadaf, Łos, Marek J., Klonisch, Thomas, Ghavami, Saeid

“…In this study, we used nitrogen-doped titanium dioxide (N-TiO 2 ) NPs in conjugation with visible light, and show that both reactive oxygen species (ROS) and…”
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