Search Results - "GHANDEHARI, H"

Transepithelial transport and toxicity of PAMAM dendrimers: Implications for oral drug delivery by Sadekar, S., Ghandehari, H.

“…This article summarizes efforts to evaluate poly(amido amine) (PAMAM) dendrimers as carriers for oral drug delivery. Specifically, the effect of PAMAM…”
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Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages by Arnida, Janát-Amsbury, M.M., Ray, A., Peterson, C.M., Ghandehari, H.

“…Compared to PEGylated gold nanospheres with slightly negative charge, near neutral PEGylated gold nanorods had increased tumor accumulation, longer circulation…”
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A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis by Yazici, Y., McAlindon, T.E., Gibofsky, A., Lane, N.E., Lattermann, C., Skrepnik, N., Swearingen, C.J., Simsek, I., Ghandehari, H., DiFrancesco, A., Gibbs, J., Tambiah, J.R.S., Hochberg, M.C.

“…Lorecivivint (LOR; SM04690), an investigational Wnt pathway modulator, previously demonstrated patient-reported and radiographic outcome improvements vs…”
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Silk-elastinlike copolymers enhance bioaccumulation of semisynthetic glycosaminoglycan ethers for prevention of radiation induced proctitis by Steinhauff, D., Jensen, M., Talbot, M., Jia, W., Isaacson, K., Jedrzkiewicz, J., Cappello, J., Oottamasathien, S., Ghandehari, H.

“…Radiation-induced proctitis (RIP) is a debilitating adverse event that occurs commonly during lower abdominal radiotherapy. The lack of prophylactic treatment…”
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Poly(amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin by Sadekar, S., Thiagarajan, G., Bartlett, K., Hubbard, D., Ray, A., McGill, L.D., Ghandehari, H.

“…Oral delivery of camptothecin has a treatment advantage but is limited by low bioavailability and gastrointestinal toxicity. Poly(amido amine) or PAMAM…”
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Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice by Sadekar, S, Ray, A, Janàt-Amsbury, M, Peterson, C. M, Ghandehari, H

“…The biodistribution profile of a series of linear N-(2-hydroxylpropyl)methacrylamide (HPMA) copolymers was compared with that of branched poly(amido amine)…”
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Advanced drug delivery 2020 - Parts 1, 2 and 3 by Ghandehari, H., Chan, H.-K., Harashima, H., MacKay, J.A., Minko, T., Schenke-Layland, K., Shen, Y., Vicent, M.J.

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Novel creation of an angiographic training model for trainees from 3D printed patient data by Eisenmenger, L, Ghandehari, H, Jensen, M, Huo, E

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Adenoviral gene delivery to solid tumors by recombinant silk-elastinlike protein polymers by HATEFI, A, CAPPELLO, J, GHANDEHARI, H

“…The purpose of this study was to investigate the potential of silk-elastinlike protein polymers (SELPs) in controlling the release rate of adenoviruses in…”
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OP15.09: Acute ovarian torsion: the impact of time delays to surgery by Glanc, P., Ghandehari, H., Kahn, D., Melamed, N.

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Abdominal obesity and the spectrum of global cardiometabolic risks in US adults by Ghandehari, H, Le, V, Kamal-Bahl, S, Bassin, S.L, Wong, N.D

“…Objective: To compare the association of obesity and abdominal obesity with cardiometabolic risk factor burden and global estimated coronary heart disease…”
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Transepithelial and endothelial transport of poly (amidoamine) dendrimers by Kitchens, Kelly M., El-Sayed, Mohamed E.H., Ghandehari, Hamidreza

“…This article summarizes our efforts to evaluate the potential of poly (amidoamine) (PAMAM) dendrimers as carriers for oral drug delivery. Specifically, the…”
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Efficacy and safety of a recombinant factor IX (Bax326) in previously treated patients with severe or moderately severe haemophilia B undergoing surgical or other invasive procedures: a prospective, open-label, uncontrolled, multicentre, phase III study by Windyga, J., Lissitchkov, T., Stasyshyn, O., Mamonov, V., Ghandehari, H., Chapman, M., Fritsch, S., Wong, W.-Y., Pavlova, B. G., Abbuehl, B. E.

“…Summary Haemostatic management of haemophilia B patients undergoing surgery is critical to patient safety. The aim of this ongoing prospective trial was to…”
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Transport mechanism(s) of poly (amidoamine) dendrimers across Caco-2 cell monolayers by El-Sayed, M., Rhodes, C.A., Ginski, M., Ghandehari, H.

“…The objective of this research was to investigate the mechanism(s) of transport of generation 2 (G2) poly (amidoamine) dendrimers across Caco-2 cell…”
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Controlled release of plasmid DNA from a genetically engineered silk-elastinlike hydrogel by MEGEED, Zaki, CAPPELLO, Joseph, GHANDEHARI, Hamidreza

“…The purpose of this study was to evaluate the potential of a genetically engineered silk-elastinlike polymer (SELP) as a matrix for the controlled release of…”
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Recombinant polymer-protein fusion: a promising approach towards efficient and targeted gene delivery by Hatefi, A., Megeed, Z., Ghandehari, H.

“…Background Synthetic vectors such as polymers have the potential to reduce the safety problems associated with viral vectors; however, their low transfection…”
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Recombinant polymers for cancer gene therapy: A minireview by Haider, M., Hatefi, A., Ghandehari, H.

“…A major challenge for successful cancer gene therapy is the development of safe and effective gene delivery vectors. Gene delivery vectors can be viral or…”
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Correction to Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice by Sadekar, S, Ray, A, Janàt-Amsbury, M, Peterson, C. M, Ghandehari, H

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Severity of symptoms, physical functioning and satisfaction in patients with lumbar spinal stenosis: a validation study of the Iranian version of the Swiss Spinal Stenosis Score by Azimi, P, Ghandehari, H S, Sadeghi, S, Azhari, S, Aghaei, H N, Mohmmadi, H R, Montazeri, A

“…A common cause of low back pain is lumbar spinal stenosis (LSS). The Swiss Spinal Stenosis Score (SSS) is a well-known questionnaire that measures the severity…”
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Comparative pharmacokinetics of PAMAM-OH dendrimers and HPMA copolymers in ovarian tumor-bearing mice by Sadekar, S., Linares, O., Noh, G. J., Hubbard, D., Ray, A., Janát-Amsbury, M., Peterson, C. M., Facelli, J., Ghandehari, H.

“…The purpose of this study was to model data from a head to head comparison of the in vivo fate of hyperbranched PAMAM dendrimers with linear HPMA copolymers in…”
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