Search Results - "GHAHRAMANI, P"

Pharmacokinetics and Safety of Voriconazole following Intravenous- to Oral-Dose Escalation Regimens by PURKINS, L, WOOD, N, GHAHRAMANI, P, GREENHALGH, K, ALLEN, M. J, KLEINERMANS, D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Randomized phase II trial of gemcitabine–cisplatin with or without trastuzumab in HER2-positive non-small-cell lung cancer by Gatzemeier, U., Groth, G., Butts, C., Van Zandwijk, N., Shepherd, F., Ardizzoni, A., Barton, C., Ghahramani, P., Hirsh, V.

“…Background: Trastuzumab provides significant clinical benefits in HER2-positive metastatic breast cancer patients when administered in combination with…”
Get full text

Phase II Study of Efficacy, Safety, and Pharmacokinetics of Trastuzumab Monotherapy Administered on a 3-Weekly Schedule by Baselga, José, Carbonell, Xavier, Castañeda-Soto, Noel-Jaime, Clemens, Michael, Green, Michael, Harvey, Vernon, Morales, Serafin, Barton, Claire, Ghahramani, Parviz

“…This phase II study investigated the efficacy, safety, and pharmacokinetics of trastuzumab monotherapy given as first-line treatment once every 3 weeks…”
Get full text

Male reproductive health under threat: Short term exposure to radiofrequency radiations emitted by common mobile jammers by Mortazavi, SMJ, Parsanezhad, M, Kazempour, M, Ghahramani, P, Mortazavi, A, Davari, M

“…Background: Modern life prompted man to increasingly generate, transmit and use electricity that leads to exposure to different levels of electromagnetic…”
Get full text

Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials by Sanmuganathan, P S, Ghahramani, P, Jackson, P R, Wallis, E J, Ramsay, L E

“…OBJECTIVE To determine the cardiovascular and coronary risk thresholds at which aspirin for primary prevention of coronary heart disease is safe and…”
Get full text

PW01-188 - Characterization of cariprazine (RGH-188) D3 /D2 receptor occupancy in healthy volunteers and schizophrenic patients by positron emission tomography (PET) by Laszlovszky, I, Gage, A, Kapas, M, Ghahramani, P

“…Objectives To evaluate the striatal D3 /D2 receptor occupancy of cariprazine (RGH-188) in healthy volunteers and schizophrenic patients, and assess the…”
Get full text

Quantitative analysis of amitriptyline and nortriptyline in human plasma and liver microsomal preparations by high-performance liquid chromatography by Ghahramani, P., Lennard, M.S.

“…A simple, rapid, highly selective and sensitive method for the analysis of amitriptyline and nortriptyline in plasma and human liver microsomes is described…”
Get full text

P.1.e.028 Dopamine D3 and D2 receptor occupancy of cariprazine in schizophrenic patients by Potkin, S, Keator, D, Mukherjee, J, Preda, A, Highum, D, Gage, A, Xie, J, Ghahramani, P, Laszlovsky, I

Get full text

PRN prescribing in psychiatric inpatients - potential for pharmacokinetic drug interactions by Davies, S., Lennard, M. S., Ghahramani, P., Pratt, P., Robertson, A., Potokar, J.

“…Abstract only…”
Get full text

Cytochromes P450 mediating the N‐demethylation of amitriptyline by Ghahramani, P., Ellis, S. W., Lennard, M. S., Ramsay, L. E., Tucker, G. T.

“…Aims Using human liver microsomes and heterologously expressed human enzymes, we have investigated the involvement of CYPs 1A2, 2C9, 2C19, 2D6 and 3A4 in the…”
Get full text

P259 Safety, tolerability and pharmacokinetics of BT051, an oral inhibitor of neutrophil migration and activation in clinical development for Inflammatory Bowel Disease by Murphy, C, Stevens, C, Hershberger, E, Quintas, M, Miller, B, Ghahramani, P

“…Abstract Background BT051 is an oral, locally acting inhibitor of neutrophil trafficking and activation in clinical development for the treatment of patients…”
Get full text

Polymeric reagent (I): Polyethyleneimine-supported silver dichromate as a new oxidizing agent by Goudarzian, N., Ghahramani, P., Hossini, S.

“…Polyethyleneimine‐supported silver dichromate is readily prepared and can be used as a stable, mild and efficient oxidizing reagent for oxidation of hydroxy…”
Get full text

Pharmacokinetics, Safety, and Efficacy of Trastuzumab Administered Every Three Weeks in Combination With Paclitaxel by LEYLAND-JONES, Brian, GELMON, Karen, AYOUB, Jean-Pierre, ARNOLD, Andrew, VERMA, Shail, DIAS, Reg, GHAHRAMANI, Parviz

“…This phase II study evaluated the pharmacokinetics and safety of trastuzumab and paclitaxel given every 3 weeks to women with human epidermal growth factor…”
Get full text

Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children by WALSH, THOMAS J, LUTSAR, IRJA, DRISCOLL, TIMOTHY, DUPONT, BERTRAND, RODEN, MAUREEN, GHAHRAMANI, PARVIS, HODGES, MICHAEL, GROLL, ANDREAS H, PERFECT, JOHN R

“…OBJECTIVE.To describe the safety and efficacy of voriconazole in children treated within the compassionate release program. METHODS.Children received…”
Get full text

Effect of renal impairment on the pharmacokinetics of levomilnacipran following a single oral dose oflevomilnacipran extended-release capsule in humans by Chen L, Greenberg WM, Brand-Schieber E, Wangsa J, Periclou A, Ghahramani P

“…Laishun Chen, William M Greenberg, Elimor Brand-Schieber, Julie Wangsa, Antonia Periclou, Parviz Ghahramani Forest Research Institute, a subsidiary of Actavis…”
Get full text

PW01-188 - Characterization Of Cariprazine (Rgh-188) D 3 /D 2 Receptor Occupancy In Healthy Volunteers And Schizophrenic Patients By Positron Emission Tomography (Pet) by Laszlovszky, I., Gage, A., Kapas, M., Ghahramani, P.

“…Objectives To evaluate the striatal D 3 /D 2 receptor occupancy of cariprazine (RGH-188) in healthy volunteers and schizophrenic patients, and assess the…”
Get full text

Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration by Purkins, Lynn, Wood, Nolan, Ghahramani, Parviz, Love, Edward R., Eve, Malcolm D., Fielding, Anitra

“…Aims  Voriconazole is a new triazole antifungal agent, and is metabolized by the cytochrome P450 isoenzymes CYP2C9, CYP2C19, and, to a lesser extent, by…”
Get full text

No clinically significant effect of erythromycin or azithromycin on the pharmacokinetics of voriconazole in healthy male volunteers by Purkins, Lynn, Wood, Nolan, Ghahramani, Parviz, Kleinermans, Diane, Layton, Gary, Nichols, Don

“…Aims  The antibiotic erythromycin is a potent inhibitor of cytochrome P450 CYP3A4 metabolism. As CYP isozymes, including CYP3A4, are involved in the metabolism…”
Get full text

The effect of the CYP3A4 inhibitor, itraconazole, on the pharmacokinetics of ZD6474 in healthy subjects by Smith, R., Oliver, S., Ghahramani, P., Kennedy, S., Gilmore, E., Duvauchelle, T., Hammett, T.

“…Abstract only…”
Get full text

The pharmacodynamic effect on cardiac repolarization of combination single dose ZD6474 and ondansetron in healthy subjects by Hammett, T., Oliver, S., Ghahramani, P., Kennedy, S., Fisher, I., Gilmore, E., Duvauchelle, T., Smith, R.

“…Abstract only…”
Get full text