Search Results - "GHAEMI, S NASSIR"

Symptomatic versus disease‐modifying effects of psychiatric drugs by Ghaemi, S. Nassir

“…Objective Drugs can be divided into two major categories, symptomatic and disease modifying. This review explores whether and how psychiatric drugs fall into…”
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The rise and fall of the biopsychosocial model by Ghaemi, S. Nassir

“…The biopsychosocial model is the conceptual status quo of contemporary psychiatry. Although it has played an important role in combatting psychiatric…”
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Drug Discovery in Psychiatry: Rethinking Conventional Wisdom by Ghaemi, S. Nassir

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Perspective: Aristotle on manic‐depressive illness and greatness by Ghaemi, S. Nassir

“…To reanalyze Aristotle's classic lecture, "On melancholy," with current clinical interpretations. The full lecture is described and interpreted in a new…”
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After the failure of DSM: clinical research on psychiatric diagnosis by Ghaemi, S. Nassir

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Mixed features of depression: why DSM-5 is wrong (and so was DSM-IV) by Koukopoulos, Athanasios, Sani, Gabriele, Ghaemi, S. Nassir

“…The DSM system has never acknowledged a central position for mixed states; thus, mixed depressions have been almost completely neglected for decades. Now,…”
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In the Tradition of William Osler: A New Biohumanistic Model of Psychiatry by Ghaemi, S Nassir

“…William Osler (1849-1919) is often considered the most influential physician in the emergence of science-based medicine. However, his approach to clinical…”
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Why antidepressants are not antidepressants: STEP-BD, STARD, and the return of neurotic depression by Nassir Ghaemi, S

“…The widely held clinical view of ‘antidepressants’ as highly effective and specific for the treatment of all types of depressive disorders is exaggerated. This…”
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Standard and trace-dose lithium: A systematic review of dementia prevention and other behavioral benefits by Mauer, Sivan, Vergne, Derick, Ghaemi, S Nassir

“…Objective: Dementia is a major public health issue, with notably high rates in persons with mood illnesses. Lithium has been shown to have considerable…”
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The bipolar spectrum: Conceptions and misconceptions by Ghaemi, S Nassir, Dalley, Shannon

“…Objective: This review aims to address concerns about the potential overinclusiveness and vagueness of bipolar spectrum concepts, and also, concerns about the…”
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Koukopoulos׳ diagnostic criteria for mixed depression: A validation study by Sani, Gabriele, Vöhringer, Paul A, Napoletano, Flavia, Holtzman, Niki S, Dalley, Shannon, Girardi, Paolo, Ghaemi, S. Nassir, Koukopoulos, Athanasios

“…Abstract Background Mixed depression (MxD) is one subtype of depressive experiences within the depressive spectrum. MxD definition is debated among experts…”
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Polypharmacy as maintenance treatment in bipolar illness: A systematic review by Amerio, Andrea, Russo, Daniel, Miletto, Norberto, Aguglia, Andrea, Costanza, Alessandra, Benatti, Beatrice, Odone, Anna, Barroilhet, Sergio A., Brakoulias, Vlasios, Dell’Osso, Bernardo, Serafini, Gianluca, Amore, Mario, Ghaemi, S. Nassir

“…ABSTRACT Objectives Polypharmacy is common in maintenance treatment of bipolar illness, but proof of greater efficacy compared to monotherapy is assumed rather…”
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Positive aspects of mental illness: A review in bipolar disorder by Galvez, Juan Francisco, Thommi, Sairah, Ghaemi, S. Nassir

“…Abstract Introduction There is growing interest to understand the role of positive psychological features on the outcomes of medical illnesses. Unfortunately…”
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Second messengers and their importance for novel drug treatments of patients with bipolar disorder by Sani, Gabriele, Kotzalidis, Georgios D., Fiaschè, Federica, Manfredi, Giovanni, Ghaemi, S. Nassir

“…Second messenger systems, like the cyclic nucleotide, glycogen synthase kinase-3β, phosphoinositide, and arachidonic acid cascades, are involved in bipolar…”
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Safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression: a systematic review and meta-analysis of randomised placebo-controlled trials by McGirr, Alexander, Dr, Vöhringer, Paul A, MD, Ghaemi, S Nassir, MD, Lam, Raymond W, MD, Yatham, Lakshmi N, Prof

“…Summary Background Although mania and hypomania define bipolar disorder, depressive episodes are more common and impairing, with few proven treatments…”
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Lithium treatment for chronic traumatic encephalopathy: A proposal by Nassir Ghaemi, S., Mauer, Sivan, Omalu, Bennet I.

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The Koukopoulos Mixed Depression Rating Scale (KMDRS): An International Mood Network (IMN) validation study of a new mixed mood rating scale by Sani, Gabriele, Vöhringer, Paul A., Barroilhet, Sergio A., Koukopoulos, Alexia E., Ghaemi, S. Nassir

“…It has been proposed that the broad major depressive disorder (MDD) construct is heterogenous. Koukopoulos has provided diagnostic criteria for an important…”
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A Useful and Sustainable Role for N‐of‐1 Trials in the Healthcare Ecosystem by Selker, Harry P., Cohen, Theodora, D’Agostino, Ralph B., Dere, Willard H., Ghaemi, S. Nassir, Honig, Peter K., Kaitin, Kenneth I., Kaplan, Heather C., Kravitz, Richard L., Larholt, Kay, McElwee, Newell E., Oye, Kenneth A., Palm, Marisha E., Perfetto, Eleanor, Ramanathan, Chandra, Schmid, Christopher H., Seyfert‐Margolis, Vicki, Trusheim, Mark, Eichler, Hans‐Georg

“…Clinicians and patients often try a treatment for an initial period to inform longer‐term therapeutic decisions. A more rigorous approach involves N‐of‐1…”
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Feeling and Time: The Phenomenology of Mood Disorders, Depressive Realism, and Existential Psychotherapy by Ghaemi, S. Nassir

“…Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are…”
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The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders by Tohen, Mauricio, Frank, Ellen, Bowden, Charles L, Colom, Francesc, Ghaemi, S Nassir, Yatham, Lakshmi N, Malhi, Gin S, Calabrese, Joseph R, Nolen, Willem A, Vieta, Eduard, Kapczinski, Flávio, Goodwin, Guy M, Suppes, Trisha, Sachs, Gary S, Chengappa, KN Roy, Grunze, Heinz, Mitchell, Philip B, Kanba, Shigenobu, Berk, Michael

“…Objectives:  Via an international panel of experts, this paper attempts to document, review, interpret, and propose operational definitions used to describe…”
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