Search Results - "GHABOOSI, Nazli"

A conditional yeast E1 mutant blocks the ubiquitin-proteasome pathway and reveals a role for ubiquitin conjugates in targeting Rad23 to the proteasome by Ghaboosi, Nazli, Deshaies, Raymond J

“…E1 ubiquitin activating enzyme catalyzes the initial step in all ubiquitin-dependent processes. We report the isolation of uba1-204, a temperature-sensitive…”
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HER2-Targeted Therapy Reduces Incidence and Progression of Midlife Mammary Tumors in Female Murine Mammary Tumor Virus huHER2-Transgenic Mice by FINKLE, David, ZHI RICKY QUAN, ERICKSON, Sharon, ASGHARI, Vida, KLOSS, Jessica, GHABOOSI, Nazli, MAI, Elaine, WAI LEE WONG, HOLLINGSHEAD, Philip, SCHWALL, Ralph, KOEPPEN, Hartmut

“…Purpose: This study examined the effectiveness of early and prolonged mu4D5 (the murine form of trastuzumab/Herceptin) treatment in transgenic mice that…”
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ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice by Erickson, Sharon L., O’Shea, K. Sue, Ghaboosi, Nazli, Loverro, Linda, Frantz, Gretchen, Bauer, Michelle, Lu, Lucy H., Moore, Mark W.

“…Heregulins bind directly to ErbB3 and ErbB4 receptors, leading to multiple dimerization possibilities including heterodimerization with the ErbB2 receptor. We…”
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Cell Death Regulation in Drosophila: Conservation of Mechanism and Unique Insights by Vernooy, Stephanie Y., Copeland, Jeffrey, Ghaboosi, Nazli, Griffin, Erik E., Yoo, Soon Ji, Hay, Bruce A.

“…Programmed cell death, or apoptosis, is a genetically encoded form of cell suicide that results in the orderly death and phagocytic removal of excess, damaged,…”
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Genetic inhibition of the ubiquitin-proteasome pathway: Insights into proteasomal targeting by Ghaboosi, Nazli

“…Regulated proteolysis plays a major role in diverse cellular processes, including cell-cycle progression, endocytosis, apoptosis, transcription, and signal…”
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Cell Death Regulation in Drosophila by Vernooy, Stephanie Y., Copeland, Jeffrey, Ghaboosi, Nazli, Griffin, Erik E., Yoo, Soon Ji, Hay, Bruce A.

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