Search Results - "GESTELAND, R. F"

Thermodynamic calculations and statistical correlations for oligo‐probes design by Matveeva, O. V., Shabalina, S. A., Nemtsov, V. A., Tsodikov, A. D., Gesteland, R. F., Atkins, J. F.

“…Optimization of probe design for array‐based experiments requires improved predictability of oligonucleotide hybridization behavior. Currently, designing…”
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Programmed Ribosomal Frameshifting: Much Ado about Knotting by Alam, S. L., Atkins, J. F., Gesteland, R. F.

“…Rules of the genetic code can be temporarily suspended to make room for a variety of specific tricks that direct synthesis of additional proteins from RNAs…”
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Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit by Ivanov, I P, Gesteland, R F, Atkins, J F

“…The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine…”
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Recoding: Reprogrammed Genetic Decoding by Gesteland, R. F., Weiss, R. B., Atkins, John F.

“…The process by which nucleic acid sequence is translated into amino acid sequence is dictated by the genetic code. The "recoding" phenomenon, in which a set of…”
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Thermodynamic criteria for high hit rate antisense oligonucleotide design by Matveeva, O. V., Mathews, D. H., Tsodikov, A. D., Shabalina, S. A., Gesteland, R. F., Atkins, J. F., Freier, S. M.

“…Antisense oligonucleotides are used for therapeutic applications and in functional genomic studies. In practice, however, many of the oligonucleotides…”
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Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity by Matveeva, O V, Tsodikov, A D, Giddings, M, Freier, S M, Wyatt, J R, Spiridonov, A N, Shabalina, S A, Gesteland, R F, Atkins, J F

“…Design of antisense oligonucleotides targeting any mRNA can be much more efficient when several activity-enhancing motifs are included and activity-decreasing…”
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rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift by Larsen, B, Wills, N M, Gesteland, R F, Atkins, J F

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A Second Mammalian Antizyme: Conservation of Programmed Ribosomal Frameshifting by Ivanov, Ivaylo P., Gesteland, Raymond F., Atkins, John F.

“…A second mammalian ornithine decarboxylase antizyme was discovered. The deduced protein sequence of the human antizyme2 is 54% identical and 67% similar to…”
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Reading two bases twice: mammalian antizyme frameshifting in yeast by Matsufuji, S, Matsufuji, T, Wills, N.M, Gesteland, R.F, Atkins, J.F

“…Programmed translational frameshifting is essential for the expression of mammalian ornithine decarboxylase antizyme, a protein involved in the regulation of…”
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Evidence that a Downstream Pseudoknot is Required for Translational Read- Through of the Moloney Murine Leukemia Virus Gag Stop Codon by Wills, Norma M., Gesteland, Raymond F., Atkins, John F.

“…Approximately 5% of the ribosomes translating the gag gene of murine leukemia viruses read through the UAG terminator and translate the in-frame pol gene to…”
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COUPLING OF OPEN READING FRAMES BY TRANSLATIONAL BYPASSING by Herr, Alan J, Atkins, John F, Gesteland, Raymond F

“…Translational bypassing joins the information found within two disparate open reading frames into a single polypeptide chain. The underlying mechanism centers…”
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Primary structure of the Saccharomyces cerevisiae GAL4 gene by Laughon, A, Gesteland, R.F

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Ribosome gymnastics--degree of difficulty 9.5, style 10.0 by Atkins, J F, Weiss, R B, Gesteland, R F

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Deletion of Selenoprotein P Alters Distribution of Selenium in the Mouse by Hill, Kristina E., Zhou, Jiadong, McMahan, Wendy J., Motley, Amy K., Atkins, John F., Gesteland, Raymond F., Burk, Raymond F.

“…Selenoprotein P (Se-P) contains most of the selenium in plasma. Its function is not known. Mice with the Se-P gene deleted (Sepp−/−) were generated. Two…”
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Frameshifting in gene 10 of bacteriophage T7 by CONDRON, B. G, ATKINS, J. F, GESTELAND, R. F

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Reading frame switch caused by base‐pair formation between the 3′ end of 16S rRNA and the mRNA during elongation of protein synthesis in Escherichia coli by Weiss, R. B., Dunn, D. M., Dahlberg, A. E., Atkins, J. F., Gesteland, R. F.

“…Watson‐Crick base pairing is shown to occur between the mRNA and nucleotides near the 3′ end of 16S rRNA during the elongation phase of protein synthesis in…”
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Programmed ribosomal frameshifting in decoding the SARS-CoV genome by Baranov, Pavel V., Henderson, Clark M., Anderson, Christine B., Gesteland, Raymond F., Atkins, John F., Howard, Michael T.

“…Programmed ribosomal frameshifting is an essential mechanism used for the expression of orf1b in coronaviruses. Comparative analysis of the frameshift region…”
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An efficient Shine-Dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli by WAGNER, L. A, GESTELAND, R. F, DAYHUFF, T. J, WEISS, R. B

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ODNBase—a web database for antisense oligonucleotide effectiveness studies by Giddings, Michael C., Matveeva, Olga V., Atkins, John F., Gesteland, Raymond F.

“…ODNBase is a database of antisense oligodeoxynucleotides targeted to mammalian mRNAs that were reported in the literature. It includes the oligo sequences…”
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Towards a Genetic Dissection of the Basis of Triplet Decoding, and its Natural Subversion: Programmed Reading Frame Shifts and Hops by Atkins, J F, Weiss, R B, Thompson, S, Gesteland, R F

“…It is perhaps surprising that the impressive fidelity of normal triplet decoding can be easily perturbed by mutants of several different translation…”
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