Search Results - "GERRY, Norman"

Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial by Lundgren, Jens D, Grund, Birgit, Barkauskas, Christina E, Holland, Thomas L, Gottlieb, Robert L, Sandkovsky, Uriel, Brown, Samuel M, Knowlton, Kirk U, Self, Wesley H, Files, D Clark, Jain, Mamta K, Benfield, Thomas, Bowdish, Michael E, Leshnower, Bradley G, Baker, Jason V, Jensen, Jens-Ulrik, Gardner, Edward M, Ginde, Adit A, Harris, Estelle S, Johansen, Isik S, Markowitz, Norman, Matthay, Michael A, Østergaard, Lars, Chang, Christina C, Goodman, Anna L, Chang, Weizhong, Dewar, Robin L, Gerry, Norman P, Higgs, Elizabeth S, Highbarger, Helene, Murray, Daniel D, Murray, Thomas A, Natarajan, Ven, Paredes, Roger, Parmar, Mahesh K B, Phillips, Andrew N, Reilly, Cavan, Rupert, Adam W, Sharma, Shweta, Shaw-Saliba, Kathryn, Sherman, Brad T, Teitelbaum, Marc, Wentworth, Deborah, Cao, Huyen, Klekotka, Paul, Babiker, Abdel G, Davey, Victoria J, Gelijns, Annetine C, Kan, Virginia L, Polizzotto, Mark N, Thompson, B Taylor, Lane, H Clifford, Neaton, James D

“…In a randomized, placebo-controlled, clinical trial, bamlanivimab, a SARS-CoV-2-neutralizing monoclonal antibody, given in combination with remdesivir, did not…”
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A genome-wide association study of hypertension and blood pressure in African Americans by Adeyemo, Adebowale, Gerry, Norman, Chen, Guanjie, Herbert, Alan, Doumatey, Ayo, Huang, Hanxia, Zhou, Jie, Lashley, Kerrie, Chen, Yuanxiu, Christman, Michael, Rotimi, Charles

“…The evidence for the existence of genetic susceptibility variants for the common form of hypertension ("essential hypertension") remains weak and inconsistent…”
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Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer by Spira, Avrum, Beane, Jennifer E, Shah, Vishal, Steiling, Katrina, Liu, Gang, Schembri, Frank, Gilman, Sean, Dumas, Yves-Martine, Calner, Paul, Sebastiani, Paola, Sridhar, Sriram, Beamis, John, Lamb, Carla, Anderson, Timothy, Gerry, Norman, Keane, Joseph, Lenburg, Marc E, Brody, Jerome S

“…Lung cancer is the leading cause of death from cancer in the US and the world. The high mortality rate (80-85% within 5 years) results, in part, from a lack of…”
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Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19 : A Randomized Controlled Trial by Barkauskas, Christina, Mylonakis, Eleftherios, Poulakou, Garyfallia, Young, Barnaby E, Vock, David M, Siegel, Lianne, Engen, Nicole, Grandits, Greg, Mosaly, Nilima R, Vekstein, Andrew M, Rogers, Ralph, Shehadeh, Fadi, Kaczynski, Matthew, Mylona, Evangelia K, Syrigos, Konstantinos N, Rapti, Vasiliki, Lye, David C, Hui, Diong Shiau, Leither, Lindsay, Knowlton, Kirk U, Jain, Mamta K, Marines-Price, Rubria, Osuji, Alice, Overcash, J Scott, Kalomenidis, Ioannis, Barmparessou, Zafeiria, Waters, Michael, Zepeda, Karla, Chen, Peter, Torbati, Sam, Kiweewa, Francis, Sebudde, Nicholus, Almasri, Eyad, Hughes, Alyssa, Bhagani, Sanjay R, Rodger, Alison, Sandkovsky, Uriel, Gottlieb, Robert L, Nnakelu, Eriobu, Trautner, Barbara, Menon, Vidya, Lutaakome, Joseph, Matthay, Michael, Robinson, Philip, Protopapas, Konstantinos, Koulouris, Nikolaos, Kimuli, Ivan, Baduashvili, Amiran, Braun, Dominique L, Günthard, Huldrych F, Ramachandruni, Srikanth, Kidega, Robert, Kim, Kami, Hatlen, Timothy J, Phillips, Andrew N, Murray, Daniel D, Jensen, Tomas O, Padilla, Maria L, Accardi, Evan X, Shaw-Saliba, Katy, Dewar, Robin L, Teitelbaum, Marc, Natarajan, Ven, Laverdure, Sylvain, Highbarger, Helene C, Rehman, M Tauseef, Vogel, Susan, Vallée, David, Crew, Page, Atri, Negin, Schechner, Adam J, Pett, Sarah, Hudson, Fleur, Badrock, Jonathan, Touloumi, Giota, Brown, Samuel M, Self, Wesley H, North, Crystal M, Ginde, Adit A, Chang, Christina C, Kelleher, Anthony, Nagy-Agren, Stephanie, Vasudeva, Shikha, Looney, David, Nguyen, Hien H, Sánchez, Adriana, Weintrob, Amy C, Grund, Birgit, Sharma, Shweta, Reilly, Cavan S, Paredes, Roger, Bednarska, Agnieszka, Gerry, Norman P, Babiker, Abdel G, Davey, Victoria J, Gelijns, Annetine C, Higgs, Elizabeth S, Kan, Virginia, Matthews, Gail, Thompson, B Taylor

“…Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. To…”
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The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population by Kay, Chris, Collins, Jennifer A., Wright, Galen E.B., Baine, Fiona, Miedzybrodzka, Zosia, Aminkeng, Folefac, Semaka, Alicia J., McDonald, Cassandra, Davidson, Mark, Madore, Steven J., Gordon, Erynn S., Gerry, Norman P., Cornejo‐Olivas, Mario, Squitieri, Ferdinando, Tishkoff, Sarah, Greenberg, Jacquie L., Krause, Amanda, Hayden, Michael R.

“…Huntington disease (HD) is the most common monogenic neurodegenerative disorder in populations of European ancestry, but occurs at lower prevalence in…”
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A genome-wide association study of serum uric acid in African Americans by Charles, Bashira A, Shriner, Daniel, Doumatey, Ayo, Chen, Guanjie, Zhou, Jie, Huang, Hanxia, Herbert, Alan, Gerry, Norman P, Christman, Michael F, Adeyemo, Adebowale, Rotimi, Charles N

“…Uric acid is the primary byproduct of purine metabolism. Hyperuricemia is associated with body mass index (BMI), sex, and multiple complex diseases including…”
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Challenges in Translating GWAS Results to Clinical Care by Scheinfeldt, Laura B, Schmidlen, Tara J, Gerry, Norman P, Christman, Michael F

“…Clinical genetic testing for Mendelian disorders is standard of care in many cases; however, it is less clear to what extent and in which situations clinical…”
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An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance by Shahabi, Payman, Scheinfeldt, Laura B, Lynch, Daniel E, Schmidlen, Tara J, Perreault, Sylvie, Keller, Margaret A, Kasper, Rachel, Wawak, Lisa, Jarvis, Joseph P, Gerry, Norman P, Gordon, Erynn S, Christman, Michael F, Dubé, Marie-Pierre, Gharani, Neda

“…Pharmacogenomics (PGx) guided warfarin dosing, using a comprehensive dosing algorithm, is expected to improve dose optimisation and lower the risk of adverse…”
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A Common Genetic Variant Is Associated with Adult and Childhood Obesity by Herbert, Alan, Gerry, Norman P., McQueen, Matthew B., Heid, Iris M., Pfeufer, Arne, Illig, Thomas, H. -Erich Wichmann, Meitinger, Thomas, Hunter, David, Hu, Frank B., Colditz, Graham, Hinney, Anke, Hebebrand, Johannes, Koberwitz, Kerstin, Zhu, Xiaofeng, Cooper, Richard, Ardlie, Kristin, Lyon, Helen, Hirschhorn, Joel N., Laird, Nan M., Lenburg, Marc E., Lange, Christoph, Christman, Michael F.

“…Obesity is a heritable trait and a risk factor for many common diseases such as type 2 diabetes, heart disease, and hypertension. We used a dense whole-genome…”
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Transferability and fine-mapping of genome-wide associated loci for adult height across human populations by Shriner, Daniel, Adeyemo, Adebowale, Gerry, Norman P, Herbert, Alan, Chen, Guanjie, Doumatey, Ayo, Huang, Hanxia, Zhou, Jie, Christman, Michael F, Rotimi, Charles N

“…Human height is the prototypical polygenic quantitative trait. Recently, several genetic variants influencing adult height were identified, primarily in…”
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Using the Coriell Personalized Medicine Collaborative Data to conduct a genome-wide association study of sleep duration by Scheinfeldt, Laura B., Gharani, Neda, Kasper, Rachel S., Schmidlen, Tara J., Gordon, Erynn S., Jarvis, Joseph P., Delaney, Susan, Kronenthal, Courtney J., Gerry, Norman P., Christman, Michael F.

“…Sleep is critical to health and functionality, and several studies have investigated the inherited component of insomnia and other sleep disorders using…”
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Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data by Lenburg, Marc E, Liou, Louis S, Gerry, Norman P, Frampton, Garrett M, Cohen, Herbert T, Christman, Michael F

“…Renal cell carcinoma is a common malignancy that often presents as a metastatic-disease for which there are no effective treatments. To gain insights into the…”
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Genetic and genomic stability across lymphoblastoid cell line expansions by Scheinfeldt, Laura B, Hodges, Kelly, Pevsner, Jonathan, Berlin, Dorit, Turan, Nahid, Gerry, Norman P

“…Lymphoblastoid cell lines are widely used in genetic and genomic studies. Previous work has characterized variant stability in transformed culture and across…”
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Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns by Tchkonia, Tamara, Lenburg, Marc, Thomou, Thomas, Giorgadze, Nino, Frampton, Garrett, Pirtskhalava, Tamar, Cartwright, Andrew, Cartwright, Mark, Flanagan, John, Karagiannides, Iordanes, Gerry, Norman, Forse, R Armour, Tchoukalova, Yourka, Jensen, Michael D, Pothoulakis, Charalabos, Kirkland, James L

“…Anatomically separate fat depots differ in size, function, and contribution to pathological states, such as the metabolic syndrome. We isolated preadipocytes…”
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UGT1A1 is a major locus influencing bilirubin levels in African Americans by CHEN, Guanjie, RAMOS, Edward, BENTLEY, Amy R, HUICHUN XU, CHARLES, Bashira A, CHRISTMAN, Michael F, ROTIMI, Charles N, ADEYEMO, Adebowale, SHRINER, Daniel, JIE ZHOU, DOUMATEY, Ayo P, HUANG, Hanxia, ERDOS, Michael R, GERRY, Norman P, HERBERT, Alan

“…Total serum bilirubin is associated with several clinical outcomes, including cardiovascular disease, diabetes and drug metabolism. We conducted a genome-wide…”
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Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients by Tripathi, Anusri, King, Chialin, de la Morenas, Antonio, Perry, Victoria Kristina, Burke, Bohdana, Antoine, Gregory A., Hirsch, Erwin F., Kavanah, Maureen, Mendez, Jane, Stone, Michael, Gerry, Norman P., Lenburg, Marc E., Rosenberg, Carol L.

“…Normal‐appearing epithelium of cancer patients can harbor occult genetic abnormalities. Data comprehensively comparing gene expression between histologically…”
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Transferability and fine mapping of genome-wide associated loci for lipids in African Americans by Adeyemo, Adebowale, Bentley, Amy R, Meilleur, Katherine G, Doumatey, Ayo P, Chen, Guanjie, Zhou, Jie, Shriner, Daniel, Huang, Hanxia, Herbert, Alan, Gerry, Norman P, Christman, Michael F, Rotimi, Charles N

“…A recent, large genome-wide association study (GWAS) of European ancestry individuals has identified multiple genetic variants influencing serum lipids…”
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Multiple loci associated with renal function in African Americans by Shriner, Daniel, Herbert, Alan, Doumatey, Ayo P, Zhou, Jie, Huang, Hanxia, Erdos, Michael R, Chen, Guanjie, Gerry, Norman P, Christman, Michael F, Adeyemo, Adebowale, Rotimi, Charles N

“…The incidence of chronic kidney disease varies by ethnic group in the USA, with African Americans displaying a two-fold higher rate than European Americans…”
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Universal DNA microarray method for multiplex detection of low abundance point mutations by Gerry, N P, Witowski, N E, Day, J, Hammer, R P, Barany, G, Barany, F

“…Cancers arise from the accumulation of multiple mutations in genes regulating cellular growth and differentiation. Identification of such mutations in numerous…”
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C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans by DOUMATEY, Ayo P, GUANJIE CHEN, JOHNSON, Thomas, OLI, Johnnie, OKAFOR, Godfrey, AMOAH, Albert, EGHAN, Benjamin A, AGYENIM-BOATENG, Kofi, ACHEAMPONG, Joseph, ADEBAMOWO, Clement, GERRY, Norman P, CHRISTMAN, Michael F, TEKOLA AYELE, Fasil, ADEYEMO, Adebowale, ROTIMI, Charles N, JIE ZHOU, ERDOS, Michael, SHRINER, Daniel, HANXIA HUANG, ADELEYE, Jokotade, BALOGUN, Williams, FASANMADE, Olufemi

“…C-reactive protein (CRP) is an acute phase reactant protein produced primarily by the liver. Circulating CRP levels are influenced by genetic and non-genetic…”
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