Search Results - "GERMAIN, L"

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma by Gapp, K., van Steenwyk, G., Germain, P. L., Matsushima, W., Rudolph, K. L. M., Manuella, F., Roszkowski, M., Vernaz, G., Ghosh, T., Pelczar, P., Mansuy, I. M., Miska, E. A.

“…Psychiatric diseases have a strong heritable component known to not be restricted to DNA sequence-based genetic inheritance alone but to also involve…”
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An advanced approach to reconstructing parent orientation maps in the case of approximate orientation relations: Application to steels by Germain, L., Gey, N., Mercier, R., Blaineau, P., Humbert, M.

“…Reconstructions allow the evaluation of the microtexture before phase transformation from that measured by EBSD after phase transformation. Even though they…”
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Deep Learning for automated phase segmentation in EBSD maps. A case study in Dual Phase steel microstructures by Martinez Ostormujof, T., Purushottam Raj Purohit, R.R.P., Breumier, S., Gey, N., Salib, M., Germain, L.

“…Electron Backscattering Diffraction (EBSD) provides important information to discriminate phase transformation products in steels. This task is conventionally…”
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Texture and microtexture variations in a near-α titanium forged disk of bimodal microstructure by Gey, N., Bocher, P., Uta, E., Germain, L., Humbert, M.

“…Quasi-alpha titanium billets often contain macrozones, i.e. large regions of sharp microtexture that differ from one region to the next and are detrimental for…”
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Spherical indexing of overlap EBSD patterns for orientation-related phases – Application to titanium by Lenthe, W.C., Germain, L., Chini, M.R., Gey, N., De Graef, M.

“…[Display omitted] We propose a new electron backscatter diffraction (EBSD) indexing approach that can handle overlapping patterns arising from fine-scale…”
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Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial by Opoku, Nicholas O, Bakajika, Didier K, Kanza, Eric M, Howard, Hayford, Mambandu, Germain L, Nyathirombo, Amos, Nigo, Maurice M, Kasonia, Kambale, Masembe, Safari L, Mumbere, Mupenzi, Kataliko, Kambale, Larbelee, Jemmah P, Kpawor, Mawolo, Bolay, Kpehe M, Bolay, Fatorma, Asare, Sampson, Attah, Simon K, Olipoh, George, Vaillant, Michel, Halleux, Christine M, Kuesel, Annette C

“…The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in sub-Saharan Africa, have motivated large morbidity…”
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Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight by Lee, Se-Jin, Lehar, Adam, Meir, Jessica U., Koch, Christina, Morgan, Andrew, Warren, Lara E., Rydzik, Renata, Youngstrom, Daniel W., Chandok, Harshpreet, George, Joshy, Gogain, Joseph, Michaud, Michael, Stoklasek, Thomas A., Liu, Yewei, Germain-Lee, Emily L.

“…Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in…”
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Life without Thyroxine to 3,5,3′-Triiodothyronine Conversion: Studies in Mice Devoid of the 5′-Deiodinases by Galton, Valerie Anne, Schneider, Mark J, Clark, Ann S, St. Germain, Donald L

“…Considerable indirect evidence suggests that the type 2 deiodinase (D2) generates T3 from T4 for local use in specific tissues including pituitary, brown fat,…”
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Interactions between ferrite recrystallization and austenite formation in high-strength steels by Chbihi, A., Barbier, D., Germain, L., Hazotte, A., Gouné, M.

“…Using both experimental and modeling approaches, we give some clarifications regarding the mechanisms of interaction between ferrite recrystallization and…”
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Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity by Wu, Zhaofei, Martinez, M. Elena, St. Germain, Donald L, Hernandez, Arturo

“…The role of thyroid hormones (TH) in the central regulation of energy balance is increasingly appreciated. Mice lacking the type 3 deiodinase (DIO3), which…”
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Influence of transformation temperature on microtexture formation associated with α precipitation at β grain boundaries in a β metastable titanium alloy by Salib, M., Teixeira, J., Germain, L., Lamielle, E., Gey, N., Aeby-Gautier, E.

“…The influence of transformation temperature on microtexture development associated with α precipitation at β/β grain boundaries (GB) in the near-β Ti17 alloy…”
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Type 3 Deiodinase, a Thyroid-Hormone-Inactivating Enzyme, Controls Survival and Maturation of Cone Photoreceptors by Ng, Lily, Lyubarsky, Arkady, Nikonov, Sergei S, Ma, Michelle, Srinivas, Maya, Kefas, Benjamin, St. Germain, Donald L, Hernandez, Arturo, Pugh, Edward N., Jr, Forrest, Douglas

“…Maturation of the mammalian nervous system requires adequate provision of thyroid hormone and mechanisms that enhance tissue responses to the hormone. Here, we…”
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Autologous bilayered self-assembled skin substitutes (SASSs) as permanent grafts: a case series of 14 severely burned patients indicating clinical effectiveness by Germain, L, Larouche, D, Nedelec, B, Perreault, I, Duranceau, L, Bortoluzzi, P, Beaudoin Cloutier, C, Genest, H, Caouette-Laberge, L, Dumas, A, Bussière, A, Boghossian, E, Kanevsky, J, Leclerc, Y, Lee, J, Nguyen, M T, Bernier, V, Knoppers, B M, Moulin, V J, Auger, F A

“…Split-thickness skin autografts (AGs) are the standard surgical treatment for severe burn injuries. However, the treatment of patients with substantial skin…”
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A Protective Role for Type 3 Deiodinase, a Thyroid Hormone-Inactivating Enzyme, in Cochlear Development and Auditory Function by Ng, Lily, Hernandez, Arturo, He, Wenxuan, Ren, Tianying, Srinivas, Maya, Ma, Michelle, Galton, Valerie A, St. Germain, Donald L, Forrest, Douglas

“…Thyroid hormone is necessary for cochlear development and auditory function, but the factors that control these processes are poorly understood. Previous…”
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Nitrogen isotope fractionation in amino acids from harbor seals: implications for compound-specific trophic position calculations by Germain, Leslie R., Koch, Paul L., Harvey, James, McCarthy, Matthew D.

“…Compound-specific isotope analysis of individual amino acids (AA) is a rapidly growing tool in ecological studies to assess diet and trophic position (TP) in…”
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Adult onset of type 3 deiodinase deficiency in mice alters brain gene expression and increases locomotor activity by Stohn, J. Patrizia, Martinez, M. Elena, St. Germain, Donald L., Hernandez, Arturo

“…[Display omitted] •Adult-onset deficiency in the type 3 deiodinase (DIO3) leads to increased locomotor activity in females.•Adult loss of DIO3 causes increases…”
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Cerebellar Abnormalities in Mice Lacking Type 3 Deiodinase and Partial Reversal of Phenotype by Deletion of Thyroid Hormone Receptor α1 by Peeters, Robin P, Hernandez, Arturo, Ng, Lily, Ma, Michelle, Sharlin, David S, Pandey, Mritunjay, Simonds, William F, St. Germain, Donald L, Forrest, Douglas

“…Thyroid hormone serves many functions throughout brain development, but the mechanisms that control the timing of its actions in specific brain regions are…”
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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A by Lee, Se-Jin, Lehar, Adam, Liu, Yewei, Ly, Chi Hai, Pham, Quynh-Mai, Michaud, Michael, Rydzik, Renata, Youngstrom, Daniel W., Shen, Michael M., Kaartinen, Vesa, Germain-Lee, Emily L., Rando, Thomas A.

“…Myostatin (MSTN) is a transforming growth factor-β (TGF-β) family member that normally acts to limit muscle growth. The function of MSTN is partially redundant…”
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Prevalence of Chiari malformation type 1 is increased in pseudohypoparathyroidism type 1A and associated with aberrant bone development by Krishnan, Neetu, McMullan, Patrick, Yang, Qingfen, Buscarello, Alexzandrea N, Germain-Lee, Emily L

“…Albright hereditary osteodystrophy (AHO) is caused by heterozygous inactivating mutations in GNAS. Patients with maternally-inherited mutations develop…”
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Type 3 Deiodinase Deficiency Causes Spatial and Temporal Alterations in Brain T3 Signaling that Are Dissociated from Serum Thyroid Hormone Levels by Hernandez, Arturo, Quignodon, Laure, Martinez, M. Elena, Flamant, Frederic, St. Germain, Donald L

“…The type 3 deiodinase (D3) is an enzyme that inactivates thyroid hormones (TH) and is highly expressed during development and in the central nervous system…”
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