Search Results - "GERMAIN, Claire"

Tertiary lymphoid structures, drivers of the anti-tumor responses in human cancers by Dieu-Nosjean, Marie-Caroline, Giraldo, Nicolas A., Kaplon, Hélène, Germain, Claire, Fridman, Wolf Herman, Sautès-Fridman, Catherine

“…Summary The characterization of the microenvironment of human tumors led to the description of tertiary lymphoid structures (TLS) characterized by mature…”
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TP53, STK11 , and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti-PD-1 in Lung Adenocarcinoma by Biton, Jérôme, Mansuet-Lupo, Audrey, Pécuchet, Nicolas, Alifano, Marco, Ouakrim, Hanane, Arrondeau, Jennifer, Boudou-Rouquette, Pascaline, Goldwasser, François, Leroy, Karen, Goc, Jeremy, Wislez, Marie, Germain, Claire, Laurent-Puig, Pierre, Dieu-Nosjean, Marie-Caroline, Cremer, Isabelle, Herbst, Ronald, Blons, Hélène, Damotte, Diane

“…By unlocking antitumor immunity, antibodies targeting programmed cell death 1 (PD-1) exhibit impressive clinical results in non-small cell lung cancer,…”
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Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention by Sautès-Fridman, Catherine, Lawand, Myriam, Giraldo, Nicolas A, Kaplon, Hélène, Germain, Claire, Fridman, Wolf Herman, Dieu-Nosjean, Marie-Caroline

“…Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates that reflect lymphoid neogenesis occurring in tissues at sites of inflammation. They are…”
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Tertiary Lymphoid Structure-Associated B Cells are Key Players in Anti-Tumor Immunity by Germain, Claire, Gnjatic, Sacha, Dieu-Nosjean, Marie-Caroline

“…It is now admitted that the immune system plays a major role in tumor control. Besides the existence of tumor-specific T cells and B cells, many studies have…”
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LLT1-CD161 Interaction in Cancer: Promises and Challenges by Braud, Veronique M, Meghraoui-Kheddar, Aïda, Elaldi, Roxane, Petti, Luciana, Germain, Claire, Anjuère, Fabienne

“…The success of immune checkpoint therapy in cancer has changed our way of thinking, promoting the design of future cancer treatments that places the immune…”
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Non-destructive optical monitoring of grape maturation by proximal sensing by Ben Ghozlen, Naïma, Cerovic, Zoran G, Germain, Claire, Toutain, Sandrine, Latouche, Gwendal

“…A new, commercial, fluorescence-based optical sensor for plant constituent assessment was recently introduced. This sensor, called the Multiplex(®) (FORCE-A,…”
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Tertiary Lymphoid Structure-B Cells Narrow Regulatory T Cells Impact in Lung Cancer Patients by Germain, Claire, Devi-Marulkar, Priyanka, Knockaert, Samantha, Biton, Jérôme, Kaplon, Hélène, Letaïef, Laïla, Goc, Jérémy, Seguin-Givelet, Agathe, Gossot, Dominique, Girard, Nicolas, Validire, Pierre, Lefèvre, Marine, Damotte, Diane, Alifano, Marco, Lemoine, François M, Steele, Keith E, Teillaud, Jean-Luc, Hammond, Scott A, Dieu-Nosjean, Marie-Caroline

“…The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell…”
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Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions by Russick, Jules, Joubert, Pierre-Emmanuel, Gillard-Bocquet, Mélanie, Torset, Carine, Meylan, Maxime, Petitprez, Florent, Dragon-Durey, Marie-Agnes, Marmier, Solenne, Varthaman, Aditi, Josseaume, Nathalie, Germain, Claire, Goc, Jérémy, Dieu-Nosjean, Marie-Caroline, Validire, Pierre, Fournel, Ludovic, Zitvogel, Laurence, Bindea, Gabriela, Lupo, Audrey, Damotte, Diane, Alifano, Marco, Cremer, Isabelle

“…BackgroundNatural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact…”
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Regulatory T cells infiltrate the tumor-induced tertiary lymphoïd structures and are associated with poor clinical outcome in NSCLC by Devi-Marulkar, Priyanka, Fastenackels, Solène, Karapentiantz, Pierre, Goc, Jérémy, Germain, Claire, Kaplon, Hélène, Knockaert, Samantha, Olive, Daniel, Panouillot, Marylou, Validire, Pierre, Damotte, Diane, Alifano, Marco, Murris, Juliette, Katsahian, Sandrine, Lawand, Myriam, Dieu-Nosjean, Marie-Caroline

“…On one hand, regulatory T cells (Tregs) play an immunosuppressive activity in most solid tumors but not all. On the other hand, the organization of…”
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Expression of LLT1 and its receptor CD161 in lung cancer is associated with better clinical outcome by Braud, Véronique M., Biton, Jérôme, Becht, Etienne, Knockaert, Samantha, Mansuet-Lupo, Audrey, Cosson, Estelle, Damotte, Diane, Alifano, Marco, Validire, Pierre, Anjuère, Fabienne, Cremer, Isabelle, Girard, Nicolas, Gossot, Dominique, Seguin-Givelet, Agathe, Dieu-Nosjean, Marie-Caroline, Germain, Claire

“…Co-stimulatory and inhibitory receptors expressed by immune cells in the tumor microenvironment modulate the immune response and cancer progression. Their…”
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1005 BiXAb® MAIT Engagers: solving the problems of classical T-cell engagers in the treatment of solid tumors by Plyte, Simon E, Fraudeau, Marie, Germain, Claire, Winterberg, Dorothee, Rousseau, Camille, Sodaro, Gaetano, Audin, Maxime, Ivagnes, Alexandre, Oberg, Hans Heinrich, Gerard, Pierre Emmanuel, Wesch, Daniela, Peipp, Matthias, Prigent, Julie

“…BackgroundMucosal-Associated Invariant T cells (MAITs) are an abundant subset of non-conventional T-cells with potent cytotoxic capacity that are resident in…”
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Anti-telomerase immune response predicts disease progression in chronic lymphocytic leukemia by Germain, Claire, Garibal, Julie, Doppler, Valérie, Baran-Marszak, Fanny, Cymbalista, Florence, Caumartin, Julien, Langlade-Demoyen, Pierre, Wehbe, Maria, Huet, Thierry

“…Human telomerase reverse transcriptase (hTERT) is broadly expressed in many cancers. High hTERT expression have been described in chronic lymphocytic leukemia…”
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Characterization of Alternatively Spliced Transcript Variants of CLEC2D Gene by Germain, Claire, Bihl, Franck, Zahn, Stefan, Poupon, Gwenola, Dumaurier, Marie-Jeanne, Rampanarivo, Hariniaina Henintsoa, Padkjær, Søren Berg, Spee, Pieter, Braud, Veronique M.

“…Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural…”
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Immunological Characterization of a Modified Vaccinia Virus Ankara Vector Expressing the Human Papillomavirus 16 E1 Protein by Remy-Ziller, Christelle, Germain, Claire, Spindler, Anita, Hoffmann, Chantal, Silvestre, Nathalie, Rooke, Ronald, Bonnefoy, Jean-Yves, Préville, Xavier

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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MHC Class I–Related Chain A Conjugated to Antitumor Antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cells by GERMAIN, Claire, LARBOURET, Christel, CESSON, Valérie, DONDA, Alena, HELD, Werner, MACH, Jean-Pierre, PELEGRIN, André, ROBERT, Bruno

“…Purpose: As a first step for the development of a new cancer immunotherapy strategy, we evaluated whether antibody-mediated coating by MHC class I–related…”
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Legal Information Management in a Global and Digital Age: Revolution and Tradition by Germain, Claire M.

“…This article presents an overview of the public policy issues surrounding digital libraries, and describes some current trends, such as Web 2.0, the social…”
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Present-Day Organic Matter Sedimentation on the NW Mediterranean Margin: Importance of Off-Shelf Export by Buscail, Roselyne, Germain, Claire

“…We present an overview of the organic matter distribution in surface sediments sampled on the Gulf of Lions margin from 600 to 2,300 m depth. Surface deposits…”
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Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer by GERMAIN, Claire, GNJATIC, Sacha, VALIDIRE, Pierre, DAMOTTE, Diane, ALIFANO, Marco, MAGDELEINAT, Pierre, CREMER, Isabelle, TEILLAUD, Jean-Luc, FRIDMAN, Wolf-Herman, SAUTES-FRIDMAN, Catherine, DIEU-NOSJEAN, Marie-Caroline, TAMZALIT, Fella, KNOCKAERT, Samantha, REMARK, Romain, GOC, Jérémy, LEPELLEY, Alice, BECHT, Etienne, KATSAHIAN, Sandrine, BIZOUARD, Geoffray

“…It is now well established that immune responses can take place outside of primary and secondary lymphoid organs. We previously described the presence of…”
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Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells by Goc, Jérémy, Germain, Claire, Vo-Bourgais, Thi Kim Duy, Lupo, Audrey, Klein, Christophe, Knockaert, Samantha, de Chaisemartin, Luc, Ouakrim, Hanane, Becht, Etienne, Alifano, Marco, Validire, Pierre, Remark, Romain, Hammond, Scott A, Cremer, Isabelle, Damotte, Diane, Fridman, Wolf-Herman, Sautès-Fridman, Catherine, Dieu-Nosjean, Marie-Caroline

“…Tumor-infiltrating T cells, particularly CD45RO(+)CD8(+) memory T cells, confer a positive prognostic value in human cancers. However, the mechanisms that…”
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Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma by Giraldo, Nicolas A, Becht, Etienne, Vano, Yann, Petitprez, Florent, Lacroix, Laetitia, Validire, Pierre, Sanchez-Salas, Rafael, Ingels, Alexandre, Oudard, Stephane, Moatti, Audrey, Buttard, Benedicte, Bourass, Sarah, Germain, Claire, Cathelineau, Xavier, Fridman, Wolf H, Sautès-Fridman, Catherine

“…The efficacy of PD-1 checkpoint blockade as adjuvant therapy in localized clear cell renal cell carcinoma (ccRCC) is currently unknown. The identification of…”
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