Search Results - "GERDJIKOV, Todor V"
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Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies
Published in Nature communications (08-04-2020)“…Assimilation of novel strategies into a consolidated action repertoire is a crucial function for behavioral adaptation and cognitive flexibility. Acetylcholine…”
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2
Segregated cholinergic transmission modulates dopamine neurons integrated in distinct functional circuits
Published in Nature neuroscience (01-08-2016)“…The authors show how dopamine neurons operate in the context of cholinergic transmission and find that the afferents originating from two functionally distinct…”
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3
Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats
Published in Psychopharmacology (01-08-2017)“…Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility…”
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4
Extrinsic Sources of Cholinergic Innervation of the Striatal Complex: A Whole-Brain Mapping Analysis
Published in Frontiers in neuroanatomy (22-01-2016)“…Acetylcholine in the striatal complex plays an important role in normal behavior and is affected in a number of neurological disorders. Although early studies…”
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5
Discrimination of Vibrotactile Stimuli in the Rat Whisker System: Behavior and Neurometrics
Published in Neuron (Cambridge, Mass.) (25-02-2010)“…Understanding the neural code underlying perception requires the mapping of physical stimulus parameters to both psychophysical decisions and neuronal…”
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6
Global Tactile Coding in Rat Barrel Cortex in the Absence of Local Cues
Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2018)“…Abstract Although whisker-related perception is based predominantly on local, near-instantaneous coding, global, intensive coding, which integrates the…”
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7
Phosphodiesterase type 1 inhibition alters medial prefrontal cortical activity during goal-driven behaviour and partially reverses neurophysiological deficits in the rat phencyclidine model of schizophrenia
Published in Neuropharmacology (15-03-2021)“…Positive modulation of cAMP signalling by phosphodiesterase (PDE) inhibitors has recently been explored as a potential target for the reversal of cognitive and…”
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8
Synchronization in the prefrontal–striatal circuit tracks behavioural choice in a go–no‐go task in rats
Published in The European journal of neuroscience (01-03-2019)“…Rodent striatum is involved in sensory‐motor transformations and reward‐related learning. Lesion studies suggest dorsolateral striatum, dorsomedial striatum…”
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Altered cortico-striatal crosstalk underlies object recognition memory deficits in the sub-chronic phencyclidine model of schizophrenia
Published in Brain Structure and Function (01-09-2017)“…The neural mechanisms underlying cognitive deficits in schizophrenia are poorly understood. Sub-chronic treatment with the NMDA antagonist phencyclidine (PCP)…”
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10
Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in rats
Published in BMC neuroscience (30-05-2006)“…The nucleus accumbens (NAc) plays a critical role in amphetamine-produced conditioned place preference (CPP). In previous studies, NAc basal and…”
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11
The head-fixed behaving rat-Procedures and pitfalls
Published in Somatosensory & motor research (01-01-2010)“…This paper describes experimental techniques with head-fixed, operantly conditioned rodents that allow the control of stimulus presentation and tracking of…”
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12
Populations of striatal medium spiny neurons encode vibrotactile frequency in rats: modulation by slow wave oscillations
Published in Journal of neurophysiology (01-01-2013)“…Dorsolateral striatum (DLS) is implicated in tactile perception and receives strong projections from somatosensory cortex. However, the sensory representations…”
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13
Rhythmic whisking area (RW) in rat primary motor cortex: an internal monitor of movement-related signals?
Published in The Journal of neuroscience (28-08-2013)“…Vibrissae-related sensorimotor cortex controls whisking movements indirectly via modulation of lower-level sensorimotor loops and a brainstem central pattern…”
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14
Amphetamine-induced enhancement of responding for conditioned reward in rats: interactions with repeated testing
Published in Psychopharmacologia (01-04-2011)“…Rationale The mesolimbic dopamine system underlies the ability of reward-related stimuli to control operant behavior. Previous work has shown that amphetamine…”
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15
Place Preference Induced by Nucleus Accumbens Amphetamine Is Impaired by Antagonists of ERK or p38 MAP Kinases in Rats
Published in Behavioral neuroscience (01-08-2004)“…The nucleus accumbens (NAc) plays a role in conditioned place preference (CPP). The authors tested the hypothesis that inhibition of mitogen-activated protein…”
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16
Discrimination of Vibrotactile Stimuli in the Rat Whisker System: Behavior and Neurometrics
Published in Neuron (Cambridge, Mass.) (10-06-2010)Get full text
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17
The role of signaling molecules in reward-related incentive learning
Published in Neurotoxicity research (2004)“…Reward-related incentive learning involves the acquisition by neutral stimuli of an enhanced ability to elicit approach and other responses. Previous studies…”
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18
Nucleus accumbens PKA inhibition blocks acquisition but enhances expression of amphetamine-produced conditioned activity in rats
Published in Psychopharmacologia (2007)“…The nucleus accumbens (NAc) plays a central role in dopamine-produced reward-related learning. In previous studies, the cyclic adenosine…”
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19
Differential effects of calcineurin inhibition and protein kinase A activation on nucleus accumbens amphetamine-produced conditioned place preference in rats
Published in The European journal of neuroscience (01-08-2005)“…The nucleus accumbens (NAc) plays a critical role in amphetamine‐produced conditioned place preference (CPP). In previous studies inhibition or activation of…”
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20
Positive and negative regulators of nucleus accumbens amphetamine-produced conditioned place preference in rats
Published 01-01-2005“…The rewarding properties of amphetamine in rats can be demonstrated using conditioned place preference (CPP). The nucleus accumbens (NAc) plays a critical role…”
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