Search Results - "GEORGE, James"
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How I treat patients with thrombotic thrombocytopenic purpura: 2010
Published in Blood (18-11-2010)“…Thrombotic thrombocytopenic purpura (TTP) is the common name for adults with microangiopathic hemolytic anemia, thrombocytopenia, with or without neurologic or…”
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Syndromes of Thrombotic Microangiopathy
Published in The New England journal of medicine (14-08-2014)“…This review article covers the diverse pathophysiological pathways that can lead to microangiopathic hemolytic anemia and a procoagulant state with or without…”
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TTP: the evolution of clinical practice
Published in Blood (11-02-2021)Get full text
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TTP: long-term outcomes following recovery
Published in Hematology (30-11-2018)“…Although risk for relapse may be the greatest concern following recovery from acquired, autoimmune thrombotic thrombocytopenic purpura (TTP), there are…”
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Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells
Published in American journal of physiology. Renal physiology (01-05-2018)“…Ferroptosis is an iron-dependent form of regulated nonapoptotic cell death, which contributes to damage in models of acute kidney injury (AKI). Heme…”
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The use of schedules in legislation: Drafting conventions, constitutional principle and statutory interpretation
Published in Statute law review (24-11-2022)“…In 'R (Maughan) Her Majesty's Senior Coroner for Oxfordshire', the Supreme Court resolved the important question of whether an inquest jury must be satisfied…”
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Thrombotic thrombocytopenic purpura: Crossing to safety
Published in Transfusion (Philadelphia, Pa.) (01-06-2022)Get full text
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Redefining outcomes in immune TTP: an international working group consensus report
Published in Blood (08-04-2021)“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal thrombotic microangiopathy caused by autoantibody-mediated severe deficiency…”
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Developing research programs that align with the clinical mission
Published in Surgery (01-04-2024)“…Building a competitive research program within a department of surgery requires a significant commitment by the department and the institution to provide the…”
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Heme Oxygenase-1 in Kidney Health and Disease
Published in Antioxidants & redox signaling (20-07-2016)“…Acute kidney injury (AKI) and chronic kidney disease (CKD) represent a considerable burden in healthcare. The heme oxygenase (HO) system plays an important…”
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Hereditary Thrombotic Thrombocytopenic Purpura
Published in The New England journal of medicine (24-10-2019)“…Hereditary thrombotic thrombocytopenic purpura is an autosomal recessive disorder caused by the absence of a functional protease (ADAMTS13) that processes von…”
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Thrombotic Thrombocytopenic Purpura
Published in The New England journal of medicine (04-05-2006)“…A 40-year-old obese black woman has had weakness and epigastric pain for several weeks and diarrhea and vomiting for four days. She does not appear acutely…”
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Thrombotic Thrombocytopenic Purpura: From 1972 to 2022 and Beyond
Published in Seminars in thrombosis and hemostasis (01-11-2022)“…This review tells the story of my personal experience with thrombotic thrombocytopenic purpura (TTP). It begins with my first encounter with TTP 50 years ago…”
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The role of rituximab in the management of patients with acquired thrombotic thrombocytopenic purpura
Published in Blood (05-03-2015)Get full text
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Triple bottom line accounting for optimizing natural gas sustainability: A statistical linear programming fuzzy ILOWA optimized sustainment model approach to reducing supply chain global cybersecurity vulnerability through information and communications technology
Published in Journal of cleaner production (20-01-2017)“…In this paper, we employed triple bottom line (TBL) accounting and considered threats to cybersecurity in the context of natural gas and global supply chain…”
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Congenital TTP: toward a turning point
Published in Blood (11-04-2019)Get full text
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Drug-induced thrombotic microangiopathy: a systematic review of published reports
Published in Blood (22-01-2015)“…Many patients with syndromes of thrombotic microangiopathy (TMA), including thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome, have been…”
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Thrombotic thrombocytopenic purpura: Toward targeted therapy and precision medicine
Published in Research and practice in thrombosis and haemostasis (01-01-2019)“…Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by severe congenital or immune‐mediated deficiency in ADAMTS13, the…”
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American Society of Hematology 2019 guidelines for immune thrombocytopenia
Published in Blood advances (10-12-2019)“…Background: Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from…”
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Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species
Published in Journal of the American Society of Nephrology (01-05-2019)“…Resident macrophages regulate homeostatic and disease processes in multiple tissues, including the kidney. Despite having well defined markers to identify…”
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