Search Results - "GENOVESE, Tiziana"
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Focus on the Role of NLRP3 Inflammasome in Diseases
Published in International journal of molecular sciences (13-06-2020)“…Inflammation is a protective reaction activated in response to detrimental stimuli, such as dead cells, irritants or pathogens, by the evolutionarily conserved…”
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Protective effect of snail secretion filtrate against ethanol-induced gastric ulcer in mice
Published in Scientific reports (11-02-2021)“…Gastric ulcer or peptic ulcer is a common disease worldwide. Basically, it develops when there is an imbalance between the protective and aggressive factors,…”
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Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice
Published in PloS one (28-03-2013)“…Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. Toll-like receptors (TLRs)…”
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Consumption of Anacardium Occidentale L . (Cashew Nuts) Inhibits Oxidative Stress through Modulation of the Nrf2/HO-1 and NF-kB Pathways
Published in Molecules (Basel, Switzerland) (26-09-2020)“…Ischemia/reperfusion injury is a severe disorder associated with a high mortality. Several antioxidant and pharmacological properties of cashew nuts ( ) and…”
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Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach
Published in International journal of molecular sciences (24-05-2021)“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and devastating clinical disorders with high mortality and no specific…”
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The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis
Published in Nutrients (20-03-2020)“…L. is a tropical plant used for the treatment of inflammatory diseases. The goal of the present work was to investigate the anti-inflammatory and anti-oxidant…”
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Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat
Published in International journal of molecular sciences (15-05-2020)“…Inflammation is known to be an essential trigger of the pathological changes that have a critical impact on nerve repair and regeneration; moreover, damage to…”
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Inhibition of P2X7 Purinergic Receptor Ameliorates Fibromyalgia Syndrome by Suppressing NLRP3 Pathway
Published in International journal of molecular sciences (16-06-2021)“…Fibromyalgia is a chronic condition characterized by persistent widespread pain that significantly reduces quality of life in patients. The purinergic P2X7…”
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Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis
Published in International journal of molecular sciences (11-05-2021)“…Endometriosis is a gynecological condition affecting patients in reproductive age. The aim of this paper was to assess the effects of the autophagy and…”
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The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways
Published in International journal of molecular sciences (13-04-2021)“…Endometriosis is a common gynecological disease. Here, we aimed to investigate the anti-fibrotic, anti-inflammatory, and anti-oxidative role of the methyl…”
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Role of Etanercept and Infliximab on Nociceptive Changes Induced by the Experimental Model of Fibromyalgia
Published in International journal of molecular sciences (30-05-2022)“…Fibromyalgia is a clinical condition that affects 1% to 5% of the population. No proper therapy has been currently found. It has been described that…”
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12
Atrazine Inhalation Causes Neuroinflammation, Apoptosis and Accelerating Brain Aging
Published in International journal of molecular sciences (26-07-2021)“…exposure to environmental contaminants has been linked to an increased risk of neurological diseases and poor outcomes. Chemical name of Atrazine (ATR) is…”
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Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema
Published in Antioxidants (01-08-2020)“…Background: Anacardium occidentale L. is a medicinal plant with powerful anti-oxidative and anti-inflammatory properties. Acute inflammatory events cause…”
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Inhibiting IL-6 in medicine: a new twist to sustain inhibition of his cytokine tin the therapy of Pulmonary Arterial Hypertension
Published in Pharmacological research (01-06-2023)“…Pulmonary arterial hypertension (PAH) is a chronic, progressive disease characterized by an increase in blood pressure in the lungs' arteries. It can occur in…”
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15
Post-ischaemic thyroid hormone treatment in a rat model of acute stroke
Published in Brain research (04-06-2013)“…Abstract Stroke is a devastating brain injury that is a leading cause of adult disability with limited treatment options. We examined the effects of prohormone…”
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Epigallocatechin-3-Gallate Modulates Postoperative Pain by Regulating Biochemical and Molecular Pathways
Published in International journal of molecular sciences (01-07-2021)“…Treating postoperative (PO) pain is a clinical challenge. Inadequate PO pain management can lead to worse outcomes, for example chronic post-surgical pain…”
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Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury
Published in International journal of molecular sciences (09-04-2022)“…Traumatic brain injury (TBI) disrupts the blood-brain barrier (BBB). Vascular endothelial growth factor (VEGF) is believed to play a key role in TBI and to be…”
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Resveratrol Inhibition of the WNT/β-Catenin Pathway following Discogenic Low Back Pain
Published in International journal of molecular sciences (07-04-2022)“…Low back pain (LBP) management is an important clinical issue. Inadequate LBP control has consequences on the mental and physical health of patients. Thus,…”
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Consumption of Cashew ( Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats
Published in Nutrients (01-04-2022)“…Hyperhomocysteinemia (HHcy) is a methionine metabolism problem that causes a variety of inflammatory illnesses. Oxidative stress is among the processes thought…”
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Açaí (Euterpe Oleraceae Mart.) Seeds Regulate NF-κB and Nrf2/ARE Pathways Protecting Lung against Acute and Chronic Inflammation
Published in Cellular physiology and biochemistry (13-05-2022)“…Respiratory diseases are the world's biggest cause of mortality and disability. Specific nutrients have been proposed to positively affect disease progression…”
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