Search Results - "GENNERO, ISABELLE"

From Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling by Briand-Mésange, Fabienne, Gennero, Isabelle, Salles, Juliette, Trudel, Stéphanie, Dahan, Lionel, Ausseil, Jérôme, Payrastre, Bernard, Salles, Jean-Pierre, Chap, Hugues

“…2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized…”
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Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia by Saint-Laurent, Celine, Garcia, Stephanie, Sarrazy, Vincent, Dumas, Karine, Authier, Florence, Sore, Sophie, Tran, Albert, Gual, Philippe, Gennero, Isabelle, Salles, Jean-Pierre, Gouze, Elvire

“…Achondroplasia is a rare genetic disease is characterized by abnormal bone development and early obesity. While the bone aspect of the disease has been…”
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Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice by Garcia, Stéphanie, Dirat, Béatrice, Tognacci, Thomas, Rochet, Nathalie, Mouska, Xavier, Bonnafous, Stéphanie, Patouraux, Stéphanie, Tran, Albert, Gual, Philippe, Le Marchand-Brustel, Yannick, Gennero, Isabelle, Gouze, Elvire

“…Achondroplasia is a rare genetic disease characterized by abnormal bone development, resulting in short stature. It is caused by a single point mutation in the…”
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HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment by Mascarau, Rémi, Bertrand, Florent, Labrousse, Arnaud, Gennero, Isabelle, Poincloux, Renaud, Maridonneau-Parini, Isabelle, Raynaud-Messina, Brigitte, Vérollet, Christel

“…HIV-1 infection is frequently associated with low bone density, which can progress to osteoporosis leading to a high risk of fractures. Only a few mechanisms…”
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SNORD116 and growth hormone therapy impact IGFBP7 in Prader–Willi syndrome by Eddiry, Sanaa, Diene, Gwenaelle, Molinas, Catherine, Salles, Juliette, Auriol, Françoise Conte, Gennero, Isabelle, Bieth, Eric, Skryabin, Boris V., Rozhdestvensky, Timofey S., Burnett, Lisa C., Leibel, Rudolph L., Tauber, Maithé, Salles, Jean Pierre

“…Purpose Prader–Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the…”
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DP2, a Carbohydrate Derivative, Enhances In Vitro Osteoblast Mineralisation by Ballout, Nissrine, Boullier, Agnès, Darwiche, Walaa, Ait-Mohand, Katia, Trécherel, Eric, Gallégo, Théo, Gomila, Cathy, Yaker, Linda, Gennero, Isabelle, Kovensky, José, Ausseil, Jérôme, Toumieux, Sylvestre

“…Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony…”
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Is ghrelin a biomarker of early-onset scoliosis in children with Prader–Willi syndrome? by Pacoricona Alfaro, Dibia Liz, Diene, Gwenaelle, Pinto, Graziella, Salles, Jean-Pierre, Gennero, Isabelle, Faye, Sandy, Molinas, Catherine, Valette, Marion, Arnaud, Catherine, Tauber, Maithé

“…Adolescents with idiopathic scoliosis display high ghrelin levels. As hyperghrelinemia is found in patients with PWS and early-onset scoliosis (EOS) is highly…”
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Hyperghrelinemia Precedes Obesity in Prader-Willi Syndrome by Feigerlová, Eva, Diene, Gwenaëlle, Conte-Auriol, Françoise, Molinas, Catherine, Gennero, Isabelle, Salles, Jean-Pierre, Arnaud, Catherine, Tauber, Maïthé

“…Background: High plasma ghrelin levels have been reported in Prader-Willi syndrome (PWS). However, little is known about plasma ghrelin in these children…”
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Human dental follicle cells acquire cementoblast features under stimulation by BMP-2/-7 and enamel matrix derivatives (EMD) in vitro by Kémoun, Philippe, Laurencin-Dalicieux, Sara, Rue, Jacqueline, Farges, Jean-Christophe, Gennero, Isabelle, Conte-Auriol, Françoise, Briand-Mesange, Fabienne, Gadelorge, Mélanie, Arzate, Higinio, Narayanan, A Sampath, Brunel, Gérard, Salles, Jean-Pierre

“…The dental follicle (DF) surrounding the developing tooth germ is an ectomesenchymal tissue composed of various cell populations derived from the cranial…”
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Diagnostic yield of bone fragility gene panel sequencing in children and young adults referred for idiopathic primary osteoporosis at a single regional reference centre by Rouleau, Coline, Malorie, Margaux, Collet, Corinne, Porquet-Bordes, Valérie, Gennero, Isabelle, Eddiry, Sanaa, Laroche, Michel, Salles, Jean Pierre, Couture, Guillaume, Edouard, Thomas

“…To describe the presenting features, bone characteristics and molecular genetics in a large monocentric cohort of children and young adults with idiopathic…”
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Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass by Gennero, Isabelle, Laurencin-Dalicieux, Sara, Conte-Auriol, Françoise, Briand-Mésange, Fabienne, Laurencin, Danielle, Rue, Jackie, Beton, Nicolas, Malet, Nicole, Mus, Marianne, Tokumura, Akira, Bourin, Philippe, Vico, Laurence, Brunel, Gérard, Oreffo, Richard O.C, Chun, Jerold, Salles, Jean Pierre

“…Abstract Lysophosphatidic acid (LPA) is a lipid mediator that acts in paracrine systems via interaction with a subset of G protein-coupled receptors (GPCRs)…”
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Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth by Tajan, Mylène, Pernin-Grandjean, Julie, Beton, Nicolas, Gennero, Isabelle, Capilla, Florence, Neel, Benjamin G, Araki, Toshiyuki, Valet, Philippe, Tauber, Maithé, Salles, Jean-Pierre, Yart, Armelle, Edouard, Thomas

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Cross-sectional associations of plasma vitamin D with cerebral β-amyloid in older adults at risk of dementia by Nourhashemi, Fati, Hooper, Claudie, Cantet, Christelle, Féart, Catherine, Gennero, Isabelle, Payoux, Pierre, Salabert, Anne Sophie, Guyonnet, Sophie, De Souto Barreto, Philipe, Vellas, Bruno

“…Vitamin D deficiency is associated with an increased risk of Alzheimer's disease and increased beta-amyloid (Aβ) in animals. Hence we sought to investigate the…”
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Ghrelin uses the GHS-R1a/Gi/cAMP pathway and induces differentiation only in mature osteoblasts. This ghrelin pathway is impaired in AIS patients by Barre, Ronan, Beton, Nicolas, Batut, Aurélie, Accabled, Frank, Sales de Gauzy, Jerome, Auriol, Françoise, Eddiry, Sanaa, Tauber, Maithe, Laurencin, Sara, Salles, Jean Pierre, Gennero, Isabelle

“…We have examined the Acylated Ghrelin (AG)/Gi pathway in different human osteoblastic cell lines. We have found that: 1) AG induces…”
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The type 1 lysophosphatidic acid receptor is involved in osteoblastogenesis up to osteocytogenesis by Alioli, Adebayo Candide, Demesmay, Léa, Laurencin, Sara, Beton, Nicolas, Farlay, Delphine, Follet, Helene, Chun, Jerold, Rivera, Richard, Bouvard, Daniel, Machuca-Gayet, Irma, Salles, Jean-Pierre, Gennero, Isabelle, Peyruchaud, Olivier

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Human dental follicle cells acquire cementoblast features under stimulation by BMP-2/-7 and enamel matrix derivatives (EMD) in vitro by Kémoun, Philippe, Laurencin-Dalicieux, Sara, Rue, Jacqueline, Farges, Jean-Christophe, Gennero, Isabelle, Conte-Auriol, Françoise, Briand-Mesange, Fabienne, Gadelorge, Mélanie, Arzate, Higinio, Narayanan, A. Sampath, Brunel, Gérard, Salles, Jean-Pierre

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Apoptotic Effect of Sphingosine 1-Phosphate and Increased Sphingosine 1-Phosphate Hydrolysis on Mesangial Cells Cultured at Low Cell Density by Gennero, Isabelle, Fauvel, Josette, Niéto, Michèle, Cariven, Clotilde, Gaits, Frédérique, Briand-Mésange, Fabienne, Chap, Hugues, Salles, Jean Pierre

“…The lipid mediator sphingosine 1-phosphate (S1P) may alter the proliferation of mesangial cells during pathophysiological processes. Here, S1P stimulated…”
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Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive behavior in Prader-Willi syndrome by Salles, Juliette, Eddiry, Sanaa, Amri, Saber, Galindo, Mélissa, Lacassagne, Emmanuelle, George, Simon, Mialhe, Xavier, Lhuillier, Émeline, Franchitto, Nicolas, Jeanneteau, Freddy, Gennero, Isabelle, Salles, Jean-Pierre, Tauber, Maithé

“…Introduction A microdeletion including the SNORD116 gene ( SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) features. PWS is a…”
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Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth by Tajan, Mylène, Pernin-Grandjean, Julie, Beton, Nicolas, Gennero, Isabelle, Capilla, Florence, Neel, Benjamin G, Araki, Toshiyuki, Valet, Philippe, Tauber, Maithé, Salles, Jean-Pierre, Yart, Armelle, Edouard, Thomas

“…Abstract Growth retardation is a constant feature of Noonan syndrome (NS) but its physiopathology remains poorly understood. We previously reported that…”
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DKK1 and sclerostin are early markers of relapse in multiple myeloma by Mabille, Charlotte, Ruyssen-Witrand, Adeline, Degboe, Yannick, Gennero, Isabelle, Loiseau, Herve Avet, Roussel, Murielle, Hebraud, Benjamin, Nigon, Delphine, Attal, Michel, Laroche, Michel

“…Recent studies have shown that Dickkopf-related protein (DKK1) and sclerostin decrease when a complete response (CR) is obtained after chemotherapy in myeloma…”
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