Search Results - "GENNARI, Luigi"

Grand Challenge in Adrenal Endocrinology: Is the Legacy of the Past a Challenge for the Future of Precision Medicine? by Chiodini, Iacopo, Gennari, Luigi

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DIAGNOSIS OF ENDOCRINE DISEASE: Evaluation of bone fragility in endocrine disorders by Eller-Vainicher, Cristina, Falchetti, Alberto, Gennari, Luigi, Cairoli, Elisa, Bertoldo, Francesco, Vescini, Fabio, Scillitani, Alfredo, Chiodini, Iacopo

“…An underlying disease affecting bone health is present in up to 40 and 60% of osteoporotic postmenopausal women and men respectively. Among the disorders…”
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Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes by Chiodini, Iacopo, Gatti, Davide, Soranna, Davide, Merlotti, Daniela, Mingiano, Christian, Fassio, Angelo, Adami, Giovanni, Falchetti, Alberto, Eller-Vainicher, Cristina, Rossini, Maurizio, Persani, Luca, Zambon, Antonella, Gennari, Luigi

“…Several studies suggest an association between serum 25-hydroxyvitamin D (25OHD) and the outcomes of Severe Acute Respiratory Syndrome Corona-Virus-2…”
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Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy by Campi, Irene, Gennari, Luigi, Merlotti, Daniela, Mingiano, Christian, Frosali, Alessandro, Giovanelli, Luca, Torlasco, Camilla, Pengo, Martino F, Heilbron, Francesca, Soranna, Davide, Zambon, Antonella, Di Stefano, Marta, Aresta, Carmen, Bonomi, Marco, Cangiano, Biagio, Favero, Vittoria, Fatti, Letizia, Perego, Giovanni Battista, Chiodini, Iacopo, Parati, Gianfranco, Persani, Luca

“…Abstract Background Vitamin D deficiency has been suggested to favor a poorer outcome of Coronavirus disease-19 (COVID-19). We aimed to assess if…”
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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline by Ralston, Stuart H, Corral‐Gudino, Luis, Cooper, Cyrus, Francis, Roger M, Fraser, William D, Gennari, Luigi, Guañabens, Núria, Javaid, M Kassim, Layfield, Robert, O'Neill, Terence W, Russell, R Graham G, Stone, Michael D, Simpson, Keith, Wilkinson, Diana, Wills, Ruth, Zillikens, M Carola, Tuck, Stephen P

“…ABSTRACT An evidence‐based clinical guideline for the diagnosis and management of Paget's disease of bone (PDB) was developed using GRADE methodology, by a…”
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Definition, Assessment, and Management of Vitamin D Inadequacy: Suggestions, Recommendations, and Warnings from the Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases (SIOMMMS) by Bertoldo, Francesco, Cianferotti, Luisella, Di Monaco, Marco, Falchetti, Alberto, Fassio, Angelo, Gatti, Davide, Gennari, Luigi, Giannini, Sandro, Girasole, Giuseppe, Gonnelli, Stefano, Malavolta, Nazzarena, Minisola, Salvatore, Pedrazzoni, Mario, Rendina, Domenico, Rossini, Maurizio, Chiodini, Iacopo

“…In the recent years, both the prescriptions of serum 25(OH)D levels assay, and vitamin D supplementation are constantly increasing, as well as the costs to be…”
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Vitamin D Deficiency and Cardiovascular Mortality: Retrospective Analysis "Siena Osteoporosis" Cohort by Pirrotta, Filippo, Cavati, Guido, Mingiano, Christian, Merlotti, Daniela, Nuti, Ranuccio, Gennari, Luigi, Palazzuoli, Alberto

“…Vitamin D is a fat-soluble vitamin that plays a key role in bone metabolism, particularly concerning the regulation of calcium and phosphate homeostasis…”
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Management of Osteoporosis in Men: A Narrative Review by Vescini, Fabio, Chiodini, Iacopo, Falchetti, Alberto, Palermo, Andrea, Salcuni, Antonio Stefano, Bonadonna, Stefania, De Geronimo, Vincenzo, Cesareo, Roberto, Giovanelli, Luca, Brigo, Martina, Bertoldo, Francesco, Scillitani, Alfredo, Gennari, Luigi

“…Male osteoporosis is a still largely underdiagnosed pathological condition. As a consequence, bone fragility in men remains undertreated mainly due to the low…”
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Management and Medical Therapy of Mild Hypercortisolism by Favero, Vittoria, Cremaschi, Arianna, Falchetti, Alberto, Gaudio, Agostino, Gennari, Luigi, Scillitani, Alfredo, Vescini, Fabio, Morelli, Valentina, Aresta, Carmen, Chiodini, Iacopo

“…Mild hypercortisolism (mHC) is defined as an excessive cortisol secretion, without the classical manifestations of clinically overt Cushing's syndrome. This…”
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Circulating Sclerostin Levels and Bone Turnover in Type 1 and Type 2 Diabetes by Gennari, Luigi, Merlotti, Daniela, Valenti, Roberto, Ceccarelli, Elena, Ruvio, Martina, Pietrini, Maria G, Capodarca, Cosimo, Franci, Maria Beatrice, Campagna, Maria Stella, Calabrò, Anna, Cataldo, Dorica, Stolakis, Konstantinos, Dotta, Francesco, Nuti, Ranuccio

“…Context: Previous observations showed a condition of low bone turnover and decreased osteoblast activity in both type 1 and 2 diabetes mellitus (DM1 and DM2)…”
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A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver by Materozzi, Maria, Resnati, Massimo, Facchi, Cecilia, Trudu, Matteo, Orfanelli, Ugo, Perini, Tommaso, Gennari, Luigi, Milan, Enrico, Cenci, Simone

“…Bone destruction, a major source of morbidity, is mediated by heightened differentiation and activity of osteoclasts (OC), highly specialized multinucleated…”
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The Potential Role of miRNAs as New Biomarkers for Osteoporosis by Bianciardi, Simone, Gennari, Luigi, Merlotti, Daniela, Materozzi, Maria

“…Osteoporosis is the most common metabolic bone disorder affecting up to 40% of postmenopausal women, characterized by a reduction in bone mass and strength…”
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Energy Metabolism and Ketogenic Diets: What about the Skeletal Health? A Narrative Review and a Prospective Vision for Planning Clinical Trials on this Issue by Merlotti, Daniela, Cosso, Roberta, Eller-Vainicher, Cristina, Vescini, Fabio, Chiodini, Iacopo, Gennari, Luigi, Falchetti, Alberto

“…The existence of a common mesenchymal cell progenitor shared by bone, skeletal muscle, and adipocytes cell progenitors, makes the role of the skeleton in…”
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Endocrine Actions of Osteocalcin by Patti, Aurora, Gennari, Luigi, Merlotti, Daniela, Dotta, Francesco, Nuti, Ranuccio

“…Osteocalcin is the most abundant noncollagenous protein of bone matrix. Once transcribed, this protein undergoes posttranslational modifications within…”
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Bone Fragility in Gastrointestinal Disorders by Merlotti, Daniela, Mingiano, Christian, Valenti, Roberto, Cavati, Guido, Calabrese, Marco, Pirrotta, Filippo, Bianciardi, Simone, Palazzuoli, Alberto, Gennari, Luigi

“…Osteoporosis is a common systemic disease of the skeleton, characterized by compromised bone mass and strength, consequently leading to an increased risk of…”
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Mutation of PFN1 Gene in an Early Onset, Polyostotic Paget-like Disease by Merlotti, Daniela, Materozzi, Maria, Bianciardi, Simone, Guarnieri, Vito, Rendina, Domenico, Volterrani, Luca, Bellan, Cristiana, Mingiano, Christian, Picchioni, Tommaso, Frosali, Alessandro, Orfanelli, Ugo, Cenci, Simone, Gennari, Luigi

“…Abstract Context Paget disease of bone (PDB) is a metabolic bone disease whose genetic cause remains unknown in up to 50% of familial patients. Objective Our…”
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Role of Advanced Glycation End-Products and Oxidative Stress in Type-2-Diabetes-Induced Bone Fragility and Implications on Fracture Risk Stratification by Cavati, Guido, Pirrotta, Filippo, Merlotti, Daniela, Ceccarelli, Elena, Calabrese, Marco, Gennari, Luigi, Mingiano, Christian

“…Type 2 diabetes (T2D) and osteoporosis (OP) are major causes of morbidity and mortality that have arelevant health and economic burden. Recent epidemiological…”
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Osteoporosis and Fragility Fractures in Type 2 Diabetes by Chiodini, Iacopo, Catalano, Antonino, Gennari, Luigi, Gaudio, Agostino

“…[...]if in the presence of reduced BMD an increased risk of fracture has to be considered, then in the presence of normal BMD an increased risk of fractures…”
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The effects of vegetarian diets on bone health: A literature review by Falchetti, Alberto, Cavati, Guido, Valenti, Roberto, Mingiano, Christian, Cosso, Roberta, Gennari, Luigi, Chiodini, Iacopo, Merlotti, Daniela

“…In these recent years many people are adopting a vegetarian type diet due to the numerous positive health effects of this regimen such as the reduction of the…”
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Dietary Vitamin D Intake in Italian Subjects: Validation of a Frequency Food Questionnaire (FFQ) by Nuti, Ranuccio, Gennari, Luigi, Cavati, Guido, Pirrotta, Filippo, Gonnelli, Stefano, Caffarelli, Carla, Tei, Luciano, Merlotti, Daniela

“…Vitamin D plays a crucial role in calcium and phosphate metabolism, relating to bone health and preventing metabolic bone disorders such as rickets and…”
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