Search Results - "GENEIX, J"
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ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines
Published in Oncogene (01-11-2007)“…Breast cancers that overexpress the ERBB2 tyrosine kinase receptor may be treated with the recombinant humanized monoclonal anti-ERBB2 antibody trastuzumab…”
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Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer
Published in Oncogene (11-01-2007)“…Common fragile sites (CFSs) are regions of chromosomal break that may play a role in oncogenesis. The most frequent alteration occurs at FRA3B, within the FHIT…”
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3
Angiogenesis as a prognostic marker in breast carcinoma with conventional adjuvant chemotherapy: a multiparametric and immunohistochemical analysis
Published in The Journal of pathology (01-02-1998)“…It has now been clearly established that quantitative immunohistochemical methods applied to tumour angiogenesis under suitable quality control conditions are…”
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4
Comparative multi-methodological measurement of ERBB2 status in breast cancer
Published in The Journal of pathology (01-03-2004)“…The ERBB2 transmembrane tyrosine kinase receptor is both a prognostic marker and a therapeutic target in breast cancer. Accurate determination of ERBB2 status…”
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5
Integrated Profiling of Basal and Luminal Breast Cancers
Published in Cancer research (Chicago, Ill.) (15-12-2007)“…Basal and luminal are two molecular subtypes of breast cancer with opposite histoclinical features. We report a combined, high-resolution analysis of genome…”
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Protein expression profiling identifies subclasses of breast cancer and predicts prognosis
Published in Cancer research (Chicago, Ill.) (01-02-2005)“…Breast cancer is a heterogeneous disease whose evolution is difficult to predict by using classic histoclinical prognostic factors. Prognostic classification…”
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Typical medullary breast carcinomas have a basal/myoepithelial phenotype
Published in The Journal of pathology (01-11-2005)“…Medullary breast cancer (MBC) is a rare, diagnostically difficult, pathological subtype. Despite being high grade, it has a good prognosis. MBC patients have…”
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8
Immunophenotypic analysis of inflammatory breast cancers: identification of an 'inflammatory signature'
Published in The Journal of pathology (01-03-2004)“…Inflammatory breast cancer (IBC) is a rare but very aggressive form of breast cancer. Its definition is based on clinical criteria, but a molecular definition…”
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Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of Breast Tumor Markers
Published in The American journal of pathology (01-10-2002)“…Emerging high-throughput screening technologies are rapidly providing opportunities to identify new diagnostic and prognostic markers and new therapeutic…”
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10
Identification and validation of an ERBB2 gene expression signature in breast cancers
Published in Oncogene (01-04-2004)“…ERBB2 is a transmembrane tyrosine kinase receptor encoded by a gene located in chromosome region 17q12. Overexpression of ERBB2, generally by way of gene…”
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11
WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
Published in Oncogene (13-09-2001)“…Secreted Frizzled-related protein 1 (SFRP1) encodes a member of a protein family that contains a cysteine-rich domain similar to the WNT-binding site of…”
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Carcinogenesis and translational controls: TACC1 is down-regulated in human cancers and associates with mRNA regulators
Published in Oncogene (15-08-2002)“…The three human TACC genes encode a family of proteins that are suspected to play a role in carcinogenesis. Their function is not precisely known; a Xenopus…”
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13
Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer
Published in Oncogene (01-01-2007)“…Common fragile sites (CFSs) are regions of chromosomal break that may play a role in oncogenesis. The most frequent alteration occurs at FRA3B, within the FHIT…”
Get full text
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14
Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer
Published in International journal of cancer (10-12-2003)“…The FHIT tumor suppressor gene, which encompasses the fragile site FRA3B at 3p14.2, is altered frequently in many types of human cancers. To determine its…”
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15
Loss of heterozygosity and linkage analysis in breast carcinoma: indication for a putative third susceptibility gene on the short arm of chromosome 8
Published in Oncogene (02-03-1995)“…We have analysed losses of heterozygosity (LOH) at eight markers from the p12-p22 region of human chromosome 8 in a panel of 113 breast tumors. LOH were…”
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16
Loss of heterozygosity at microsatellite markers from region p11-21 of chromosome 8 in microdissected breast tumor but not in peritumoral cells
Published in International journal of oncology (01-11-2002)“…Alterations of chromosomal region 8p11-21 are very frequent in human cancers, and especially in breast cancer; yet, most of the genes involved have not been…”
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Prognosis of breast‐carcinoma lymphagenesis evaluated by immunohistochemical investigation of vascular‐endothelial‐growth‐factor receptor 3
Published in International journal of cancer (20-01-2000)“…Very few studies have yet addressed the question of the existence and role of lymphagenesis in tumor growth; it is generally overshadowed by the greater…”
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18
Chromosome region 8p11-p21: Refined mapping and molecular alterations in breast cancer
Published in Genes chromosomes & cancer (01-07-1998)“…Several genes, most of them unknown, of the short arm of chromosome 8 are involved in malignant diseases. Numerous studies have implicated a portion of the…”
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Tissue microarrays a powerful tool in transfer and quality control in oncology
Published in Bulletin du cancer (01-01-2003)“…The progress in the knowledge of molecular genetics and the availability of high-throughput technologies offer the opportunity to identify new diagnostic and…”
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Small but high throughput: how "tissue-microarrays" became a favorite tool for pathologists and scientists
Published in Annales de pathologie (01-12-2003)“…Progress in the knowledge of molecular genetics and availability of high-throughput technologies offer the opportunity to identify new diagnostic and…”
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