Search Results - "GENAU, Heide Marika"

CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling by Genau, Heide Marika, Huber, Jessica, Baschieri, Francesco, Akutsu, Masato, Dötsch, Volker, Farhan, Hesso, Rogov, Vladimir, Behrends, Christian

“…The small Rho GTPase RAC1 is an essential regulator of cellular signaling that controls actin rearrangements and cell motility. Here, we identify a novel CUL3…”
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Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis by DOHERTY, Joanne R, CHUNYING YANG, TORTOSA, Mariola, GENAU, Heide Marika, ROUNBEHLER, Robert J, YUNQI LU, DANG, Chi V, KUMAR, K. Ganesh, BUTLER, Andrew A, BANNISTER, Thomas D, HOOPER, Andrea T, UNSAL-KACMAZ, Keziban, SCOTT, Kristen E. N, ROUSH, William R, CLEVELAND, John L, CAMERON, Michael D, FALLAHI, Mohammad, WEIMIN LI, HALL, Mark A, AMELIO, Antonio L, MISHRA, Jitendra K, FANGZHENG LI

“…Myc oncoproteins induce genes driving aerobic glycolysis, including lactate dehydrogenase-A that generates lactate. Here, we report that Myc controls…”
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Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9 by Jung, Jennifer, Genau, Heide Marika, Behrends, Christian

“…The serine/threonine kinase mTORC1 regulates cellular homeostasis in response to many cues, such as nutrient status and energy level. Amino acids induce mTORC1…”
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GABARAP proteins as scaffolds in localized TIAM1-RAC1 signaling by Genau, Heide Marika, Behrends, Christian

“…Spatially restricted signaling is a hallmark of RAC1 signaling. Recent work has uncovered a novel role of gamma-aminobutyric acid receptor-associated proteins…”
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